NCT04043533Source recordAI-normalized
The Effect of an Exercise Program in Reducing the Severity of Postpartum Depression in Women: A Randomized Control Trial
The study investigates the effectiveness of an exercise program in alleviating postpartum depression among women in Turkey. Given the reported prevalence of 23.8% for postpartum depression in the region, there is a significant market opportunity for non-pharmacological interventions that can be integrated into maternal healthcare. The findings could support the development of exercise-based therapeutic programs, potentially leading to partnerships with healthcare providers and wellness organizations focused on maternal mental health. Competitive implications include positioning against pharmacological treatments and other behavioral therapies, emphasizing the cost-effectiveness and accessibility of exercise interventions.
AI analysis
Indication: Depression, Postpartum
Modality: behavioral intervention
Target: Postpartum Depression (PPD) severity reduction through exercise intervention.
Sponsor: Didem Kucukkelepce
Source URL: ClinicalTrials.gov
Source updated: Aug 02, 2019
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Depression, Postpartum
Condition normalized: Depression, Postpartum
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Postpartum Depression (PPD) severity reduction through exercise intervention.
Target normalized: Postpartum Depression (PPD) severity reduction through exercise intervention.
NCT05215314Source recordAI-normalized
Neurobiological Mechanisms of Perceived Stress and Their Modification Through Behavioral Intervention
The study, sponsored by the University of Wisconsin, Madison, evaluates an app-based meditation program aimed at reducing perceived stress among healthy adults. With increasing awareness of mental health and wellness, particularly in the wake of the COVID-19 pandemic, this intervention could tap into a growing market for digital mental health solutions. The competitive landscape includes various mindfulness and meditation apps, but the unique focus on neurobiological correlates may provide a differentiated value proposition. Diligence should focus on user engagement, retention rates, and potential partnerships with healthcare providers or mental health organizations.
AI analysis
Indication: Stress
Modality: behavioral intervention
Target: Neurobiological mechanisms related to perceived stress and behavioral correlates, specifically focusing on the hippocampus and its role in stress regulation.
Sponsor: University of Wisconsin, Madison
Source URL: ClinicalTrials.gov
Source updated: Feb 06, 2025
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Stress, Behavior
Condition normalized: Stress, Behavior
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Neurobiological mechanisms related to perceived stress and behavioral correlates, specifically focusing on the hippocampus and its role in stress regulation.
Target normalized: Neurobiological mechanisms related to perceived stress and behavioral correlates, specifically focusing on the hippocampus and its role in stress regulation.
NCT04935593Source recordAI-normalized
Strengthening Social, Emotional and Behavioral Resilience: The RENEW (Resilience in Emotional and Behavioral Wellbeing) Pilot Randomized Controlled Trial
The RENEW pilot randomized controlled trial, sponsored by Taipei Medical University, addresses the growing prevalence of behavioral and emotional disorders among children, particularly ASD, which is currently estimated at 1 in 54. The intervention employs a multidisciplinary approach integrating social and emotional learning, gamification, and faith-centered values, targeting at-risk populations. Given the rising demand for effective interventions in mental health, particularly in pediatric populations, this study positions itself within a niche market that combines educational technology and mental health support. The focus on spiritual health outcomes and the participatory approach may differentiate RENEW from existing interventions, potentially leading to a unique market position. However, the trial's success will depend on demonstrating efficacy and scalability, which could attract interest from educational institutions and mental health organizations. Competitive implications include the need to monitor similar interventions and emerging technologies in the mental health space.
AI analysis
Indication: Neurodevelopmental Disorders
Modality: behavioral intervention
Target: Social, emotional, and behavioral resilience in children at risk for behavioral and emotional disorders, particularly focusing on Autism Spectrum Disorders (ASD).
Sponsor: Taipei Medical University
Source URL: ClinicalTrials.gov
Source updated: Mar 24, 2022
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Neurodevelopmental Disorders, Emotional Disorder, Behavior Disorders
Condition normalized: Neurodevelopmental Disorders, Emotional Disorder, Behavior Disorders
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Social, emotional, and behavioral resilience in children at risk for behavioral and emotional disorders, particularly focusing on Autism Spectrum Disorders (ASD).
Target normalized: Social, emotional, and behavioral resilience in children at risk for behavioral and emotional disorders, particularly focusing on Autism Spectrum Disorders (ASD).
NCT02038192Source recordAI-normalized
Living With Hope: Pilot Study of the Living With Hope Program for Family Caregivers of Persons With Dementia Residing in Long Term Care Facilities
The 'Living With Hope' program aims to enhance the quality of life and emotional well-being of family caregivers of dementia patients in long-term care facilities. Given the increasing prevalence of dementia and the associated caregiver burden, this program addresses a significant unmet need in supportive care. The pilot study's findings could inform larger-scale interventions and potential partnerships with healthcare organizations and caregivers' associations. The results may also open avenues for funding opportunities and collaborations in mental health and caregiver support sectors. However, the lack of a pharmaceutical or device component may limit traditional investment interest, necessitating a focus on social impact and healthcare outcomes.
AI analysis
Indication: Dementia
Modality: behavioral intervention
Target: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
Sponsor: University of Alberta
Source URL: ClinicalTrials.gov
Source updated: Jan 08, 2015
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Dementia
Condition normalized: Dementia
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
Target normalized: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
NCT03037099Source recordAI-normalized
Enhancing Glycemic Index Knowledge and Application Among Adults With Type-2 Diabetes Mellitus
The HEALD-GI study, sponsored by Athabasca University, aims to enhance dietary education focused on the Glycemic Index for adults with Type 2 Diabetes Mellitus (T2DM). With a growing global prevalence of diabetes, effective dietary management strategies are critical. This study's findings could inform future dietary interventions and educational programs, potentially leading to improved patient outcomes and reduced healthcare costs. The results may also position Athabasca University and its collaborators as leaders in diabetes management research, opening avenues for partnerships with healthcare providers and nutrition-focused organizations. The competitive landscape includes other diabetes education programs, but HEALD-GI's focus on GI may provide a unique selling proposition.
AI analysis
Indication: Type 2 Diabetes
Modality: behavioral intervention
Target: Glycemic Index (GI) dietary education and its impact on dietary behavior and glycemic control in adults with Type 2 Diabetes Mellitus.
Sponsor: Athabasca University
Source URL: ClinicalTrials.gov
Source updated: Jul 10, 2018
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Type 2 Diabetes
Condition normalized: Type 2 Diabetes
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Glycemic Index (GI) dietary education and its impact on dietary behavior and glycemic control in adults with Type 2 Diabetes Mellitus.
Target normalized: Glycemic Index (GI) dietary education and its impact on dietary behavior and glycemic control in adults with Type 2 Diabetes Mellitus.
NCT01246349Source recordAI-normalized
Motivational Interviewing as an Intervention to Increase Adolescent Self-Efficacy and Promote Weight Loss
The study, sponsored by The Hospital for Sick Children, evaluated the efficacy of Motivational Interviewing (MI) in promoting weight loss and self-efficacy among adolescents aged 10-18 years with obesity. Given the rising prevalence of childhood obesity, this intervention addresses a significant public health concern. The results could position MI as a viable therapeutic approach in pediatric obesity management, potentially leading to market opportunities in behavioral health interventions. Competitive implications include the need to assess existing behavioral therapies and their effectiveness compared to MI. Diligence should focus on the scalability of MI in clinical settings and potential partnerships with obesity clinics and health organizations.
AI analysis
Indication: Childhood Obesity
Modality: behavioral intervention
Target: Motivational Interviewing (MI) as a behavioral intervention to enhance intrinsic motivation and self-efficacy in overweight adolescents.
Sponsor: The Hospital for Sick Children
Source URL: ClinicalTrials.gov
Source updated: Nov 17, 2017
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Childhood Obesity
Condition normalized: Childhood Obesity
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Motivational Interviewing (MI) as a behavioral intervention to enhance intrinsic motivation and self-efficacy in overweight adolescents.
Target normalized: Motivational Interviewing (MI) as a behavioral intervention to enhance intrinsic motivation and self-efficacy in overweight adolescents.
NCT03601663Source recordAI-normalized
Exploring the Effect of an eHealth Intervention on Women's Physical Activity Behaviour
The University of Ottawa's pilot study explores the efficacy of an eHealth intervention aimed at increasing physical activity among overweight or obese women aged 18-65. Given the rising prevalence of obesity and associated chronic diseases, this intervention addresses a significant public health concern. The integration of wearable technology with autonomy-supportive behavioral strategies may offer a novel approach to enhancing physical activity levels in this demographic. The findings could inform future commercial applications in health tech, particularly in developing targeted interventions for women's health. Competitively, this study positions the University of Ottawa within the growing market of digital health solutions, emphasizing the importance of personalized and supportive health interventions. Diligence implications include assessing the scalability of the intervention and potential partnerships with wearable technology companies.
AI analysis
Indication: Physical Activity
Modality: behavioral intervention
Target: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
Sponsor: University of Ottawa
Source URL: ClinicalTrials.gov
Source updated: Mar 24, 2020
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Physical Activity
Condition normalized: Physical Activity
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
Target normalized: Not applicable; the study focuses on behavioral interventions rather than a specific molecular or mechanistic target.
NCT00623792Source recordAI-normalized
Preoperative Lifestyle Intervention in Bariatric Surgery
The trial, sponsored by Duquesne University, evaluates a preoperative lifestyle intervention aimed at improving outcomes for bariatric surgery candidates. Given the rising prevalence of obesity and the increasing demand for bariatric procedures, successful outcomes from this intervention could enhance patient compliance and reduce postoperative complications, potentially leading to broader adoption in clinical practice. The competitive landscape includes various lifestyle and behavioral modification programs, but this trial's focus on a structured preoperative intervention may differentiate it. The findings could inform future guidelines and reimbursement strategies, impacting market dynamics in obesity management.
AI analysis
Indication: Severe Obesity
Modality: behavioral intervention
Target: Preoperative lifestyle intervention targeting diet, exercise, and surgical preparation.
Sponsor: Duquesne University
Source URL: ClinicalTrials.gov
Source updated: Mar 17, 2016
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Severe Obesity, Bariatric Surgery
Condition normalized: Severe Obesity, Bariatric Surgery
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Preoperative lifestyle intervention targeting diet, exercise, and surgical preparation.
Target normalized: Preoperative lifestyle intervention targeting diet, exercise, and surgical preparation.
NCT06995638Source recordAI-normalized
Web-based Technology and Cognitive Training: Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study
The MUST Study, sponsored by Rutgers University, aims to develop a web-based cognitive training intervention targeting executive control in cognitively healthy older adults. This demographic is increasingly relevant due to the growing aging population and the associated risk of cognitive decline and Alzheimer's disease. The study's focus on a digital intervention aligns with current trends in telehealth and digital therapeutics, presenting potential commercial opportunities in the cognitive health market. If successful, the findings could lead to scalable cognitive training solutions, positioning Rutgers and its collaborators as leaders in the cognitive health space. The involvement of the National Institute on Aging (NIA) adds credibility and may facilitate future funding or partnerships. However, competition from existing cognitive training platforms and emerging digital health solutions must be considered during market entry strategies.
AI analysis
Indication: Healthy Aging
Modality: behavioral intervention
Target: Cognitive performance enhancement through executive control training.
Sponsor: Rutgers, The State University of New Jersey
Source URL: ClinicalTrials.gov
Source updated: Dec 15, 2025
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Healthy Aging, Alzheimer's Disease (AD)
Condition normalized: Healthy Aging, Alzheimer's Disease (AD)
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Cognitive performance enhancement through executive control training.
Target normalized: Cognitive performance enhancement through executive control training.
NCT03467594Source recordAI-normalized
BE@Work: A Pilot Controlled Before and After Trial of a Workplace Physical Activity Programme.
BE@Work (Brief Exercise at Work) is a pilot controlled before and after trial of a workplace physical activity programme.
AI analysis
Indication: High-intensity Interval Training
Modality: behavioral intervention
Target: High-intensity interval training
Sponsor: Teesside University
Source URL: ClinicalTrials.gov
Source updated: Apr 10, 2019
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: High-intensity Interval Training
Condition normalized: High-intensity Interval Training
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: High-intensity interval training
Target normalized: High-intensity interval training
NCT04550273Source recordAI-normalized
The Effect of Aerobic Exercise on Liver Enzymes in Overweight Prediabetic Patients With Hepatitis c
Exercise is one of the most vital components of health maintenance. Exercising regularly maintains the cardiovascular system health, promotes the health of liver, and declines the risks of complications induced by CHCV. Since overweight is the main risk factor for IR and type 2 DM which may speed the liver disease progression among HCV patients, exercise is very important for maintenance and loss of weight. Further, exercise can relieve the side effects of medications of HCV, improve immunity, promote a sense of well-being, reduce levels of chronic fatigue, improve blood oxygen levels and increase the endorphins excretion which makes the patients fully energized (Elgendi, Shebl A, Sliem M, and Gary FA, 2018). Studies on exercise effect in patients with CHCV are quite scarce (de Sousa Fernandes et al., 2019). Decreased leptin levels by exercise positively modulate insulin signaling and inhibit pathology progression (Anaruma et al., 2019). Since studies investigated physical activity effect on regulating HCV related leptin levels are very little, the present study aimed to explore the response of serum leptin and liver enzymes to aerobic exercise in nondiabetic overweight men with CHCV.
AI analysis
Indication: Hepatitis C
Modality: behavioral intervention
Target: aerobic treadmill exercise
Sponsor: Cairo University
Source URL: ClinicalTrials.gov
Source updated: Sep 16, 2020
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Hepatitis C
Condition normalized: Hepatitis C
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: aerobic treadmill exercise
Target normalized: aerobic treadmill exercise
NCT00692653Source recordAI-normalized
Personal Patient Profile Prostate (P4) Randomized, Multisite Trial
The purpose of this study is to determine whether or not participation in an experimental program called the "P4 program" is useful to men who are faced with choices about treatment for their early stage prostate cancer. The P4 program consists of a series of questions and information for the participant. Before seeing the cancer specialist, participants will answer several questionnaires on a computer. This will take about 20-30 minutes. Participants may choose to do this on a computer at home or on a touch-screen computer in the clinic. Half the participants will then be shown several highly rated informational websites about prostate cancer treatments. The other half, based on the individual participant's answers, will receive the P4 program's customized written and on-screen information. Reading the information and watching videos will take about 20 minutes. About one month later, and again 6 months, participants will complete follow-up questionnaires electronically or by mail. These questionnaires will help us understand how each participant's decision for treatment of their prostate cancer went. Answering these questionnaires should take about 20 minutes each time.
AI analysis
Indication: Prostate Cancer
Modality: behavioral intervention
Target: P4
Sponsor: Dana-Farber Cancer Institute
Source URL: ClinicalTrials.gov
Source updated: May 04, 2015
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Prostate Cancer
Condition normalized: Prostate Cancer
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: P4
Target normalized: P4
NCT00194493Source recordAI-normalized
Computerized Assessment for Patients With Cancer
The traditional procedure for cancer symptom and quality of life instrument administration is a paper questionnaire completed by the patient or research participant. The use of standardized, patient report instruments as routine assessment in clinical cancer care has been promoted, but infrequently reported and the utilization rate is low. Barriers to clinical use include the personnel cost of data collection, management of written questionnaires and the clinicians' unfamiliarity with the nature of the queries and numerical scale scores. Web-based electronic technology now has been developed and tested for feasibility using touchscreen, notebook computers and the computerized assessment program, a screening assessment providing usable and easily interpreted graphic output to cancer clinicians. The purpose of this study is to design and evaluate the clinical integration of the web-based computerized assessment in a major, multi-disciplinary academic medical center and cancer center. Consecutive outpatients who are evaluated for cancer therapy in each of the 2 setting sites, the University of Washington Medical Center and the Seattle Cancer Care Alliance, are able to communicate in English (or through one of the many interpreters available at the institutions), and are competent to understand the study information and give informed consent will be invited to participate. Clinicians caring for the patients in the sample will be invited to participate in evaluating the organizational impact. We will compare the outcomes of conducting assessment in the usual practices and procedures to the outcomes of using the computerized assessment program: appropriateness of referrals, efficiency, and usability. The computerized assessment will be completed prior to each participant's visit with the clinician, conducted at the first clinic visit, during the 4-6th week of treatment and again at a 30 day follow up visit. Graphical output will be immediately available to clinicians. Descriptive, comparative statistics will be used to evaluate the impact of the screening and longitudinal assessments.
AI analysis
Indication: Neoplasms
Modality: behavioral intervention
Target: ESRA-C
Sponsor: Dana-Farber Cancer Institute
Source URL: ClinicalTrials.gov
Source updated: May 04, 2015
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Neoplasms
Condition normalized: Neoplasms
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: ESRA-C
Target normalized: ESRA-C
NCT01844999Source recordAI-normalized
Personal Patient Profile - Prostate (P3P) II: Effectiveness-Implementation Trial in Diverse Health Care Networks
The purpose of this study is to determine whether using the P3P website can increase decisional preparation and satisfaction, and decrease decisional conflict, in men deciding how to manage early stage prostate cancer.
AI analysis
Indication: Prostate Cancer
Modality: behavioral intervention
Target: Personal Patient Profile - Prostate (P3P), Standard prostate cancer information websites
Sponsor: Dana-Farber Cancer Institute
Source URL: ClinicalTrials.gov
Source updated: Jan 31, 2018
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Prostate Cancer
Condition normalized: Prostate Cancer
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Personal Patient Profile - Prostate (P3P), Standard prostate cancer information websites
Target normalized: Personal Patient Profile - Prostate (P3P), Standard prostate cancer information websites
NCT03871686Source recordAI-normalized
Improving Well-being Among Young Adult Survivors of Childhood Brain Tumor: A Randomized Controlled Trial of a Brief Internet-based Behavioral Activation Program
The purpose of this study is to evaluate the effectiveness of an Internet-based, behavioral activation intervention to promote well-being in a young adult survivors of childhood brain tumor.
AI analysis
Indication: Brain Tumor, Pediatric
Modality: behavioral intervention
Target: Brief Internet-based Behavioral Activation Intervention
Sponsor: University of Wisconsin, Madison
Source URL: ClinicalTrials.gov
Source updated: Feb 05, 2020
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Brain Tumor, Pediatric
Condition normalized: Brain Tumor, Pediatric
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Brief Internet-based Behavioral Activation Intervention
Target normalized: Brief Internet-based Behavioral Activation Intervention
NCT05126823Source recordAI-normalized
Efficacy of a Combined Acceptance and Commitment Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients: a Randomized Controlled Clinical Trial
Introduction: emotional and physical alterations frequently appear in cancer patients. In this sense, interventions based on acceptance and commitment therapy (ACT) show their efficacy to improve these symptoms through increased psychological flexibility, however, there is little evidence of the efficacy of ACT using combined modality (face-to-face + app), despite the fact that this application modality may have beneficial effects in this group of patients, who may see their participation in the interventions limited as a consequence of the disease. Method / design: Cancer patients will be randomly assigned to one of the following groups: (1) face-to-face ACT + app group, (2) face-to-face ACT group, and (3) group receiving usual treatment. The planned interventions last between 8 and 10 weeks and include experiential exercises, metaphors, discussions, and homework assignments to promote awareness and flexibility about thoughts and emotions associated with cancer. In the group that uses the app, exercises (mindfulness, breathing), reminder systems, recording, reinforcement and monitoring will also be provided. It is estimated that a total of 112 participants (38 per group) will be necessary, and four evaluations will be carried out: T0 (pre-treatment), T1 (post-treatment, T2 (follow-up at three months) and T3 (follow-up at six months). months). Hypothesis : The primary results that are expected to be obtained are a significant increase in the psychological flexibility of patients receiving treatment, with greater flexibility in the group receiving the combined intervention, evaluated with the AAQ-II. Furthermore, as secondary outcomes, it is expected to obtain significant improvements in anxiety and depression (HADS), quality of life (EORTC QLQ C-30), Fatigue (BFI), Insomnia (ISI) and post-traumatic growth (PTGI-SF). Hypothesis: the efficacy of the ACT-based intervention in cancer patients may be increased if the benefits of using a modality that combines face-to-face and not face-to-face are added to it.
AI analysis
Indication: Cancer
Modality: behavioral intervention
Target: Acceptance and commitment therapy + app, Acceptance and commitment therapy
Sponsor: Francisco Garcia Torres
Source URL: ClinicalTrials.gov
Source updated: May 05, 2026
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Cancer
Condition normalized: Cancer
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Acceptance and commitment therapy + app, Acceptance and commitment therapy
Target normalized: Acceptance and commitment therapy + app, Acceptance and commitment therapy
NCT01944748Source recordAI-normalized
Family Mediation Program For At-Risk Youth
The goal of this project is to conduct a pilot evaluation of a parent-child mediation program for at-risk youth. It is investigating whether families who receive parent-child mediation show greater improvement in family functioning, as well as adolescent substance use, academic performance, and delinquency, over a 6-week and 12-week period compared to a wait-list control sample.
AI analysis
Indication: Family Functioning
Modality: behavioral intervention
Target: Families Able To Resolve Situations (FARS)
Sponsor: RAND
Source URL: ClinicalTrials.gov
Source updated: Apr 06, 2016
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Family Functioning
Condition normalized: Family Functioning
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Families Able To Resolve Situations (FARS)
Target normalized: Families Able To Resolve Situations (FARS)
NCT01535001Source recordAI-normalized
Structured Non-operative Treatment of Knee Osteoarthritis - a Randomized Controlled Trial of Pain, Physical Function and Quality of Life With 12months Follow-up
The purpose of this study is to test whether an algorithm for systematic non-surgical treatment consisting of corrective insoles, neuromuscular training, weight loss, patient education and pharmacological treatment with paracetamol, non steroidal anti inflammatory drugs (NSAIDs) and Pantoprazole provides further improvement in pain, function and quality of life than standard non-surgical treatment (information on the disease and how to treat it) in patients with knee osteoarthritis. The H1-hypothesis is that the treatment algorithm results in a greater increase in quality of life and functional capacity and greater reduction in pain than standard treatment at the primary endpoint, which is follow-up 12months after the start of the treatment. See statistical analysis plan available under "Links" for further description of the study.
AI analysis
Indication: Osteoarthritis of the Knee
Modality: behavioral intervention
Target: Neuromuscular training (NEMEX-TJR), Information, Paracetamol, Burana, Pantoprazole, Dietary counseling, Patient education, Insoles
Sponsor: Northern Orthopaedic Division, Denmark
Source URL: ClinicalTrials.gov
Source updated: Oct 16, 2017
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Osteoarthritis of the Knee
Condition normalized: Osteoarthritis of the Knee
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Neuromuscular training (NEMEX-TJR), Information, Paracetamol, Burana, Pantoprazole, Dietary counseling, Patient education, Insoles
Target normalized: Neuromuscular training (NEMEX-TJR), Information, Paracetamol, Burana, Pantoprazole, Dietary counseling, Patient education, Insoles
NCT05276544Source recordAI-normalized
The Effect of Telephone and Video Counseling Given to Obese Individuals on Weight Loss and Quality of Life in the COVID-19 Pandemic: an RCT
Individuals with obesity are at higher risk for severe disease, hospitalizations, and death from the SARS-CoV-2 virus. Social distancing guidelines intended to prevent viral spread during the COVID-19 pandemic resulted in major changes to daily routines . Several studies have demonstrated that individuals with overweight/obesity reported worsening mental health, poor eating habits , less physical activity (PA) since the onset of the COVID-19 pandemic. Because of these pandemic rules, the use of phone/video consultancy applications and online classes for body weight control and diet monitoring is increasing. Therefore, in this study it is aimed to determine the effect of diet counseling via phone or video on weight loss and to compare it with the traditional follow-up method in the COVID-19 pandemic.
AI analysis
Indication: Weight Loss
Modality: behavioral intervention
Target: Dietary intervention
Sponsor: Ankara University
Source URL: ClinicalTrials.gov
Source updated: Jul 20, 2022
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Weight Loss, Obesity
Condition normalized: Weight Loss, Obesity
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Dietary intervention
Target normalized: Dietary intervention
NCT04818255Source recordAI-normalized
Stimulation to Improve Memory: PET Education & Disclosure
When dementia is caused by AD, we refer to it as dementia of the Alzheimer's Type (DAT). The greatest risk factor for Alzheimer's Disease (AD) and DAT is advancing age, but DAT is not a normal part of aging. Studies have shown that changes in the brain happen before full symptoms of DAT develop. These changes include a buildup of two proteins within the brain, called amyloid and tau. The two goals of this study are (1) to determine whether patients with mild cognitive impairment or dementia-Alzheimer's type (DAT) are able to demonstrate decisional capacity to engage in PET amyloid and tau disclosure after receiving education; and (2) to assess how patients and care partners react to PET amyloid and tau biomarker disclosure.
AI analysis
Indication: Mild Cognitive Impairment
Modality: behavioral intervention
Target: PET Biomarker Disclosure
Sponsor: University of Michigan
Source URL: ClinicalTrials.gov
Source updated: Jan 29, 2026
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Mild Cognitive Impairment, Dementia; Alzheimer's Type (Etiology)
Condition normalized: Mild Cognitive Impairment, Dementia; Alzheimer's Type (Etiology)
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: PET Biomarker Disclosure
Target normalized: PET Biomarker Disclosure
NCT06296511Source recordAI-normalized
The Influence of Acute Moderate-intensity Continuous Exercise on Appetite Regulation
A key area of obesity research has focused on the link between appetite, energy balance and weight control. Within this area, several appetite-related hormones and cellular cytokines have been identified as key signals influencing appetite and food intake. This includes the appetite-suppressing hormone oxyntomodulin (OXM) and a cellular stress-induced cytokine growth differentiation factor 15 (GDF-15). The aims of this study are: (1) to investigate the effect of acute moderate-intensity continuous exercise on oxyntomodulin and GDF-15 concentrations; (2) to investigate whether exercise-induced changes in circulating OXM and GDF-15 concentrations are correlated with subjective appetite perceptions and subsequent energy intake.
AI analysis
Indication: Obesity
Modality: behavioral intervention
Target: Exercise
Sponsor: Loughborough University
Source URL: ClinicalTrials.gov
Source updated: Mar 06, 2024
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Obesity, Overweight
Condition normalized: Obesity, Overweight
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Exercise
Target normalized: Exercise
NCT03669692Source recordAI-normalized
Open Randomized Clinical Trial to Evaluate the Effects of Intermittent Caloric Restriction in Patients With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.
Lower urinary tract symptoms (LUTS) include filling, emptying or post-voiding state alterations; producing symptomatology depending of the underline mechanism. Benign prostatic hyperplasia (BPH) is the most common underlying disease, which increases with age and significantly affects men over 50 years. There are currently no prevention or curative treatment guidelines, as their pathophysiological mechanism is not exactly known. Several factors have been implicated, such as hormones, aging, lifestyle or diet. BPH is associated with metabolic disorders, the basis of which is insulin resistance and its associated pathologies: diabetes, hypertension, obesity, dyslipidemia and metabolic syndrome. Patients without these metabolic signs have a lower incidence of BPH and / or LUTS. Insulin resistance (IR) is associated with greater proliferation and a reduction of cellular apoptosis at the prostate level; leading to an increase in prostate volume or symptoms. Likewise, the autonomic nervous system (ANS) imbalance, both in favor of sympathetic (emptying symptoms) or parasympathetic (filling symptoms), influences LUTS. SNA activity can be measured non-invasively, repetitively and effectively by measuring the heart rate variability (HRV). Caloric restriction with optimal nutrition (CRON, hereinafter only CR) is the most physiologically adapted nutritional alternative to our ancestral needs and has been shown in humans to reduce insulin resistance and associated pathologies. It has also been observed that CR improves the balance of the SNA and allows to improve LUTS. Proliferation inhibition and prostatic apoptosis induction, mediated through CR, by insulin-IGF-1 axis reduction and mTOR metabolic pathways inhibition, are the central axis of this project. CR will be used to reduce insulin resistance, IGF expression and inhibition of the PI3K / AKT / mTOR pathway, to reduce prostate cell proliferation and promote prostatic tissue apoptosis; in this way it will be possible to reduce its volume and improve the symptomatology. Additionally, CR will allow us to evaluate the potential benefits it has on certain metabolic diseases (diabetes, dyslipidemia, obesity, hypertension, etc.), anthropometric values (BMI, abdominal perimeter and skin folds) and autonomic nervous system functionality (HRV) .
AI analysis
Indication: Prostatic Hyperplasia, Benign
Modality: behavioral intervention
Target: Caloric Restriction, Control
Sponsor: Complexo Hospitalario Universitario de A Coruña
Source URL: ClinicalTrials.gov
Source updated: Aug 02, 2021
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Prostatic Hyperplasia, Benign, Metabolic Syndrome
Condition normalized: Prostatic Hyperplasia, Benign, Metabolic Syndrome
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Caloric Restriction, Control
Target normalized: Caloric Restriction, Control
NCT04162977Source recordAI-normalized
Well-Venture Pilot Project: Adapting Personality-Targeted Interventions for Reducing Substance Misuse and Related Outcomes in Youth in Youth Protection Services
Substance use problems are major concern in adolescents involved in Youth Protection Services. However, there is an enormous gap between the needs and availability of interventions for youth with substance use problems in the system. The present study will examine the feasibility and proof-of-concept of implementing an evidence-based, personality-targeted drug and alcohol prevention programme for high-risk adolescents (i.e., Preventure programme) receiving services from Youth Protection Services. Our goal is to examine the effects of these interventions on reducing rates of substance use outcomes, depression symptoms, and self-reported anxiety sensitivity and impulsivity at 3- and 6-month post-intervention. These primary outcomes were selected based on previous Preventure trials with the community samples, that indicated these factors largely accounted for the long-term intervention effects on improving substance use outcomes. The study will be conducted at Batshaw Youth and Family Centres, which provide psychosocial, rehabilitation and social integration services and services related to child placement and adoption to English-speaking youth from all regions of Quebec. Adolescents receiving services from Batshaw centres (N = 100, aged 14 and above) will be invited to participate in the study. All interested adolescents will be invited to attend one assessment session with the research team. Participants who score high on one of subscales of Substance Use Risk Profile Scale (SURPS) (i.e., high-risk adolescents) will be invited to participate in two 90-minute group-based intervention sessions, which target their dominant personality profile. Sessions will be cognitive-behavioural in nature and are designed to help youth understand the target personality trait and develop adaptive coping strategies for managing that trait using motivational and cognitive restructuring techniques. The primary outcomes will be measured at baseline before receiving the interventions and then with 3-month and 6-month intervals after receiving the interventions to test whether these outcomes are significantly reduced after receiving the interventions. The results of this study will be used to plan the future directions of personality-targeted interventions for youth involved in Youth Protection Services.
AI analysis
Indication: Substance Use Disorders
Modality: behavioral intervention
Target: Personality-targeted Interventions
Sponsor: St. Justine's Hospital
Source URL: ClinicalTrials.gov
Source updated: Oct 26, 2020
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Substance Use Disorders, Youth Protection Services, Early Intervention, Prevention, Adolescent Development
Condition normalized: Substance Use Disorders, Youth Protection Services, Early Intervention, Prevention, Adolescent Development
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Personality-targeted Interventions
Target normalized: Personality-targeted Interventions
NCT06529965Source recordAI-normalized
Evaluating a Digital Intervention for Alleviating Diabetes-specific Emotional Distress in Adults Living With Type 2 Diabetes Mellitus: Randomized Controlled Trial
Gaia AG's covivio is positioned within the growing digital health market, specifically targeting the management of emotional distress in adults with Type 2 Diabetes Mellitus (T2DM). The trial's focus on emotional well-being complements traditional diabetes management, potentially enhancing patient adherence and overall treatment outcomes. Given the increasing prevalence of T2DM and the associated psychological burden, successful results could lead to significant market opportunities. The competitive landscape includes other digital therapeutics and mental health applications, necessitating a robust differentiation strategy. Diligence should focus on regulatory pathways, reimbursement models, and integration with existing diabetes care frameworks.
AI analysis
Indication: Glucose Metabolism Disorders (Including Diabetes Mellitus)
Modality: behavioral intervention
Target: Digital therapeutic intervention aimed at alleviating diabetes-specific emotional distress through cognitive behavioral therapy (CBT) techniques.
Sponsor: Gaia AG
Source URL: ClinicalTrials.gov
Source updated: Nov 08, 2024
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Glucose Metabolism Disorders (Including Diabetes Mellitus), Metabolic Disease, Endocrine System Diseases, Diabetes Mellitus, Type 2
Condition normalized: Glucose Metabolism Disorders (Including Diabetes Mellitus), Metabolic Disease, Endocrine System Diseases, Diabetes Mellitus, Type 2
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Digital therapeutic intervention aimed at alleviating diabetes-specific emotional distress through cognitive behavioral therapy (CBT) techniques.
Target normalized: Digital therapeutic intervention aimed at alleviating diabetes-specific emotional distress through cognitive behavioral therapy (CBT) techniques.
NCT02456636Source recordAI-normalized
Rural Engagement in Primary Care for Optimizing Weight Reduction (RE-POWER)
The purpose of this study is to compare three methods for managing obesity in rural patients, to see which method will result in patients being able to attain their weight loss goal and maintain that weight loss.
AI analysis
Indication: Obesity
Modality: behavioral intervention
Target: Fee-for-Service Model (FFS, In clinic individual visits), Patient Centered Medical Home (PCMH, In clinic group visits), Disease Management (DM, Phone group visits)
Sponsor: University of Kansas Medical Center
Source URL: ClinicalTrials.gov
Source updated: Dec 07, 2020
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Obesity
Condition normalized: Obesity
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Fee-for-Service Model (FFS, In clinic individual visits), Patient Centered Medical Home (PCMH, In clinic group visits), Disease Management (DM, Phone group visits)
Target normalized: Fee-for-Service Model (FFS, In clinic individual visits), Patient Centered Medical Home (PCMH, In clinic group visits), Disease Management (DM, Phone group visits)
NCT05502692Source recordAI-normalized
A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care
The ADVANCE clinical trial compared three recommended first-line regimens two containing dolutegravir head-to-head and demonstrated virological non-inferiority at 48- and 96-weeks respectively1,2, paving the way for the mass- introduction of dolutegravir-containing regimens across low- and- middle-income countries. The dolutegravir-containing regimens in ADVANCE were very well tolerated and demonstrated remarkable viral re-suppression in patients with viraemia when adherence measures were instituted, even in the presence of genotypically-documented resistance1,2. Across Africa, including South Africa, and in many other low- and middle-income countries, the combination of tenofovir disoproxil fumarate/lamivudine (or emtricitabine) /dolutegravir has been rolled out to millions of patients, much of this with Unitaid support to research, programmes and communities. Most ADVANCE patients have since transitioned out of the study and are on tenofovir disoproxil fumarate/lamivudine/dolutegravir in South African public sector clinics in central Johannesburg. One of the unanticipated findings of ADVANCE and the concomitant Unitaid-supported NAMSAL3 study in Cameroon, as well as analyses of registration studies and observational studies, was the consistent finding that patients on dolutegravir experience significant weight gain and new-onset obesity. It remains unclear whether this is a feature of the integrase inhibitor class (and aggravated by tenofovir alafenamide), or whether other factors are at play - it is possible that HIV infection itself may predispose to weight gain in successfully treated patients, and other antiretrovirals may alter weight trajectories. The signal has been met with alarm by the public health community, as many countries where TLD is being rolled out are experiencing a parallel obesity epidemic. Obesity is strongly associated with adverse outcomes, including diabetes, cardio-vascular-disease (CVD), sleep apnoea, gastrointestinal and muscular-skeletal disorders, asthma, poor pregnancy outcomes, many cancers, mental health issues, and poor COVID-19 outcomes. In many countries with large antiretroviral programmes, these concurrent epidemics have significant public health and financial implications, and clarification of the extent of the obesity signal is urgent.
AI analysis
Indication: Dolutegravir
Modality: behavioral intervention
Target: CHARACTERISE
Sponsor: University of Witwatersrand, South Africa
Source URL: ClinicalTrials.gov
Source updated: May 24, 2023
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Dolutegravir
Condition normalized: Dolutegravir
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: CHARACTERISE
Target normalized: CHARACTERISE
NCT06539988Source recordAI-normalized
Advancing Decisions About Virtual Service Encounters (ADViSE)
Expanded availability of virtual care encounters in Primary Care provides new opportunities to improve Veterans' outcomes by aligning encounter modalities with their needs and preferences. Yet, Veterans and their Primary Care physicians (PCPs) lack personalized information about the benefits and costs of different Primary Care modalities that is needed to maximize the value of Primary Care encounters. To address this problem, in this study the investigators will use surveys and interviews to identify what Veterans and PCPs perceive to be the benefits and optimal uses of different Primary Care encounter modalities. They will then supplement their existing system for communicating encounter costs to Veterans and PCPs with new interactive messaging about benefits and optimal uses of different encounter modalities. Finally, this novel Advancing Decisions about Virtual Service Encounters (ADViSE) intervention will be optimized through user-centered refinement before evaluating its effects on Veteran-centered outcomes, use of virtual care, and intermediate health outcomes in a randomized controlled trial (RCT).
AI analysis
Indication: Health Care Costs
Modality: behavioral intervention
Target: Clinician Coaching Sessions, Personalized text messages to patients
Sponsor: VA Office of Research and Development
Source URL: ClinicalTrials.gov
Source updated: Apr 08, 2026
Ingested: Jun 07, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Health Care Costs, Delivery of Health Care
Condition normalized: Health Care Costs, Delivery of Health Care
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Clinician Coaching Sessions, Personalized text messages to patients
Target normalized: Clinician Coaching Sessions, Personalized text messages to patients
NCT06631794Source recordAI-normalized
Evaluation of the Impact of a HPV Vaccination Talk with Third Grade Students on Their Papillomavirus Vaccination Coverage.
This observational study aims to evaluate the impact of a brief educational talk on HPV vaccination among 3rd grade students in public secondary schools. The study will compare vaccination rates in communes receiving the talk versus control communes. The expected outcome is an increase in HPV vaccine dispensing among young people born in 2010.
AI analysis
Indication: Teenagers
Modality: behavioral intervention
Target: HPV Vaccination Coverage
Sponsor: Hopital Foch
Source URL: ClinicalTrials.gov
Source updated: Oct 08, 2024
Ingested: Jun 05, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Teenagers
Condition normalized: Teenagers
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: A short talk about the importance of HPV vaccination
Target normalized: HPV Vaccination Coverage
NCT05081622Source recordAI-normalized
Preventing Violence by Teachers in Primary Schools in Haiti: A Cluster Randomized Controlled Trial of Interaction Competencies With Children - for Teachers (ICC-T)
The study evaluates the effectiveness of the Interaction Competencies with Children - for Teachers (ICC-T) intervention in reducing teacher violence in primary schools in Haiti. Conducted by Bielefeld University, the trial involves 36 schools and aims to improve children's mental health, academic performance, and overall well-being.
AI analysis
Indication: Violence by Teachers
Modality: behavioral intervention
Target: Violence by Teachers
Sponsor: Bielefeld University
Source URL: ClinicalTrials.gov
Source updated: Feb 06, 2025
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Violence by Teachers
Condition normalized: Violence by Teachers
Modality raw: Violence by Teachers
Modality normalized: behavioral intervention
Target raw: Violence by Teachers
Target normalized: Violence by Teachers
NCT05753020Source recordAI-normalized
A Pilot Study of The CKM JumpStart Tool
This pilot study evaluates the CKM JumpStart Tool, aimed at enhancing discussions about conservative kidney management (CKM) between older patients with advanced CKD and their healthcare providers. The study involves 76 participants aged 75 and older, assessing the tool's feasibility and acceptability.
AI analysis
Indication: Chronic Kidney Diseases
Modality: behavioral intervention
Target: Chronic Kidney Diseases
Sponsor: University of Washington
Source URL: ClinicalTrials.gov
Source updated: Aug 09, 2024
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Chronic Kidney Diseases
Condition normalized: Chronic Kidney Diseases
Modality raw: Chronic Kidney Diseases
Modality normalized: behavioral intervention
Target raw: Chronic Kidney Diseases
Target normalized: Chronic Kidney Diseases
NCT04395872Source recordAI-normalized
Psychiatric Consultation for COVID-19 Patients
This study aims to evaluate the effectiveness of psychiatric counseling for patients admitted to a COVID-19 care unit. It focuses on assessing the emotional state of patients and the impact of psychological interventions on their mental health.
AI analysis
Indication: Covid19
Modality: behavioral intervention
Target: Psychiatric support for COVID-19 patients
Sponsor: Daegu Catholic University Medical Center
Source URL: ClinicalTrials.gov
Source updated: May 27, 2020
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Covid19
Condition normalized: Covid19
Modality raw: Covid19
Modality normalized: behavioral intervention
Target raw: Psychiatric support for COVID-19 patients
Target normalized: Psychiatric support for COVID-19 patients
NCT03967782Source recordAI-normalized
Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity: the TIMEX 2 Study
The TIMEX 2 study, conducted by University Hospital, Clermont-Ferrand, aimed to evaluate the impact of exercise timing relative to meals on energy intake and appetite in adolescents with obesity. The study involved 18 participants and assessed their responses to three conditions: control (rest), exercise before lunch, and exercise after lunch.
AI analysis
Indication: Pediatric obésity
Modality: behavioral intervention
Target: Pediatric obesity
Sponsor: University Hospital, Clermont-Ferrand
Source URL: ClinicalTrials.gov
Source updated: Jun 11, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Pediatric obésity
Condition normalized: Pediatric obésity
Modality raw: Pediatric obésity
Modality normalized: behavioral intervention
Target raw: Pediatric obesity
Target normalized: Pediatric obesity
NCT04626037Source recordAI-normalized
CLC Parent-Child Emotional Preparation Program
The CLC Parent-Child Emotional Preparation Program aims to assess the feasibility of the WECS Relational Health Toolkit for enhancing emotional connections between mothers and preschool-aged children. The study involves virtual group sessions designed to integrate emotional preparation into preschool education, potentially leading to improved developmental outcomes.
AI analysis
Indication: Emotional Connection
Modality: behavioral intervention
Target: Emotional connection and child development in preschoolers
Sponsor: Columbia University
Source URL: ClinicalTrials.gov
Source updated: Nov 21, 2024
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Emotional Connection
Condition normalized: Emotional Connection
Modality raw: Emotional Connection
Modality normalized: behavioral intervention
Target raw: Emotional connection and child development in preschoolers
Target normalized: Emotional connection and child development in preschoolers
NCT07175896Source recordAI-normalized
Community-based Diet Intervention for Kidney Health in Black Americans
The Dine and DASH Into Wellness Pilot Study aims to assess the feasibility and acceptability of a 16-week diet coaching program, enhanced with cooking classes, to improve adherence to the DASH diet among Black adults at risk for chronic kidney disease (CKD). This study addresses a significant health disparity, focusing on dietary interventions to reduce cardiovascular disease mortality in this population.
AI analysis
Indication: Chronic Kidney Disease
Modality: behavioral intervention
Target: Chronic Kidney Disease in Black Americans
Sponsor: Duke University
Source URL: ClinicalTrials.gov
Source updated: Jan 15, 2026
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Chronic Kidney Disease
Condition normalized: Chronic Kidney Disease
Modality raw: Chronic Kidney Disease
Modality normalized: behavioral intervention
Target raw: Chronic Kidney Disease in Black Americans
Target normalized: Chronic Kidney Disease in Black Americans
NCT05413577Source recordAI-normalized
Reducing Parental Stress Via Instant Messaging During COVID-19 Pandemic: A Randomized Controlled Trial
This clinical trial, conducted by the Chinese University of Hong Kong, aimed to reduce parental stress through a mindfulness training intervention delivered via instant messaging applications. The study enrolled 491 parents and assessed the impact of a two-week mindfulness program on mental well-being and parenting behavior.
AI analysis
Indication: Parents
Modality: behavioral intervention
Target: Parents experiencing stress during the COVID-19 pandemic
Sponsor: Chinese University of Hong Kong
Source URL: ClinicalTrials.gov
Source updated: Nov 23, 2022
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Parents
Condition normalized: Parents
Modality raw: Parents
Modality normalized: behavioral intervention
Target raw: Parents experiencing stress during the COVID-19 pandemic
Target normalized: Parents experiencing stress during the COVID-19 pandemic
NCT00241813Source recordAI-normalized
Stress Reduction: Impact on Blood Pressure in African American Youth
This clinical trial evaluated the impact of behavioral stress reduction programs (Mindfulness Meditation and Lifeskills) on blood pressure control among African American adolescents. The study aimed to address the high prevalence of essential hypertension in this demographic by implementing preventive behavioral interventions in a school setting.
AI analysis
Indication: Cardiovascular Diseases
Modality: behavioral intervention
Target: Blood Pressure in African American Youth
Sponsor: Medical University of South Carolina
Source URL: ClinicalTrials.gov
Source updated: Dec 17, 2012
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Cardiovascular Diseases
Condition normalized: Cardiovascular Diseases
Modality raw: Cardiovascular Diseases
Modality normalized: behavioral intervention
Target raw: Blood Pressure in African American Youth
Target normalized: Blood Pressure in African American Youth
NCT02466360Source recordAI-normalized
What Are the Brakes and Levers of Physical Activity Practice for Patients With Chronic Lower Back Pain : a Qualitative Study
What Are the Brakes and Levers of Physical Activity Practice for Patients With Chronic Lower Back Pain : a Qualitative Study is a registry-stage clinical asset sponsored by University Hospital, Clermont-Ferrand in Non-specific Chronic Lower Back Pain. SEO and diligence focus: Back Belief questionnaire, QUEBEC scale, Fear Avoidance beliefs questionnaire, Visual analog scale, individual interviews, Focus groups, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Non-specific Chronic Lower Back Pain
Modality: behavioral intervention
Target: Back Belief questionnaire, QUEBEC scale, Fear Avoidance beliefs questionnaire, Visual analog scale, individual interviews, Focus groups
Sponsor: University Hospital, Clermont-Ferrand
Source URL: ClinicalTrials.gov
Source updated: Jun 09, 2015
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Non-specific Chronic Lower Back Pain
Condition normalized: Non-specific Chronic Lower Back Pain
Modality raw: fibrosis
Modality normalized: behavioral intervention
Target raw: Back Belief questionnaire, QUEBEC scale, Fear Avoidance beliefs questionnaire, Visual analog scale, individual interviews, Focus groups
Target normalized: Back Belief questionnaire, QUEBEC scale, Fear Avoidance beliefs questionnaire, Visual analog scale, individual interviews, Focus groups
NCT05732285Source recordAI-normalized
A Pilot Randomized Controlled Trial of A Comprehensive Cognitive and Affective Intervention for Neurocognitive Disorders (CoINTEGRATE)
A Pilot Randomized Controlled Trial of A Comprehensive Cognitive and Affective Intervention for Neurocognitive Disorders (CoINTEGRATE) is a NA clinical asset sponsored by University of Michigan in Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis, Mild Cognitive Impairment. SEO and diligence focus: CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Neurocognitive Disorders
Modality: behavioral intervention
Target: CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation
Sponsor: University of Michigan
Source URL: ClinicalTrials.gov
Source updated: Oct 20, 2025
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Neurocognitive Disorders
Condition normalized: Neurocognitive Disorders
Modality raw: long COVID
Modality normalized: behavioral intervention
Target raw: CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation
Target normalized: CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation
NCT06404073Source recordAI-normalized
RECOVER-ENERGIZE: A Platform Protocol for Evaluation of Interventions for Exercise Intolerance in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
RECOVER-ENERGIZE: A Platform Protocol for Evaluation of Interventions for Exercise Intolerance in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) is a NA clinical asset sponsored by Duke University in Long COVID, Long Covid19, Long Covid-19. SEO and diligence focus: Structured Pacing, Usual Care, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Long COVID
Modality: behavioral intervention
Target: Structured Pacing, Usual Care
Sponsor: Duke University
Source URL: ClinicalTrials.gov
Source updated: May 06, 2026
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Long COVID
Condition normalized: Long COVID
Modality raw: long COVID
Modality normalized: behavioral intervention
Target raw: Structured Pacing, Usual Care
Target normalized: Structured Pacing, Usual Care
NCT02170779Source recordAI-normalized
Developing and Testing a Comprehensive MS Spasticity Management Program
Developing and Testing a Comprehensive MS Spasticity Management Program is a PHASE2 clinical asset sponsored by VA Office of Research and Development in Multiple Sclerosis, Spasticity. SEO and diligence focus: Spasticity: Take Control, Usual care, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Multiple Sclerosis
Modality: behavioral intervention
Target: Spasticity: Take Control, Usual care
Sponsor: VA Office of Research and Development
Source URL: ClinicalTrials.gov
Source updated: Mar 28, 2017
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Multiple Sclerosis
Condition normalized: Multiple Sclerosis
Modality raw: multiple sclerosis
Modality normalized: behavioral intervention
Target raw: Spasticity: Take Control, Usual care
Target normalized: Spasticity: Take Control, Usual care
NCT06894654Source recordAI-normalized
DERMATOMICS: Identifying Regulators of Skin Homeostasis
DERMATOMICS: Identifying Regulators of Skin Homeostasis is a registry-stage clinical asset sponsored by Relation Therapeutics in Systemic Sclerosis (SSc). SEO and diligence focus: Skin punch biopsy, blood sampling, Questionnaire, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Systemic Sclerosis (SSc)
Modality: behavioral intervention
Target: Skin punch biopsy, blood sampling, Questionnaire
Sponsor: Relation Therapeutics
Source URL: ClinicalTrials.gov
Source updated: Jul 28, 2025
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Systemic Sclerosis (SSc)
Condition normalized: Systemic Sclerosis (SSc)
Modality raw: fibrosis
Modality normalized: behavioral intervention
Target raw: Skin punch biopsy, blood sampling, Questionnaire
Target normalized: Skin punch biopsy, blood sampling, Questionnaire
NCT02475954Source recordAI-normalized
Telehealth Cognitive-Behavioral Therapy for Depression in Parkinson's Disease
Telehealth Cognitive-Behavioral Therapy for Depression in Parkinson's Disease is a NA clinical asset sponsored by VA Office of Research and Development in Depression, Parkinson's Disease. SEO and diligence focus: TH-CBT, Standard Care, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Depression
Modality: behavioral intervention
Target: TH-CBT, Standard Care
Sponsor: VA Office of Research and Development
Source URL: ClinicalTrials.gov
Source updated: Jul 28, 2023
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Depression
Condition normalized: Depression
Modality raw: Parkinson disease
Modality normalized: behavioral intervention
Target raw: TH-CBT, Standard Care
Target normalized: TH-CBT, Standard Care
NCT06712225Source recordAI-normalized
Combining Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: a Pilot Study of Multidimensional Effects
The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related brain changes. The main questions it aims to answer are: * Does the protocol improve naming skills ? * Do the improvements observed transfer to discourse abilities ? * Are there any brain changes induced by this protocol ? Researchers will compare anomia therapy alone to anomia therapy + executive function training to see if the latter works better. Participants will: * Have a whole language assessment and a Magnetic Resonance Imaging (MRI) scan in the hospital before and after the protocol * Receive 18 sessions of the protocol, 3 times a week during 6 weeks, in the hospital * Have several naming assessments during the protocol
AI analysis
Indication: Aphasia, Acquired
Modality: behavioral intervention
Target: Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
Sponsor: University Hospital, Montpellier
Source URL: ClinicalTrials.gov
Source updated: Dec 02, 2024
Ingested: May 21, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: behavioral intervention
View original source fields
Condition raw: Aphasia, Acquired, Speech Therapy
Condition normalized: Aphasia, Acquired, Speech Therapy
Modality raw: behavioral intervention
Modality normalized: behavioral intervention
Target raw: Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
Target normalized: Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment