TrialSignal
Clinical trial intelligence report
Efficacy and Mechanisms of Combined Aerobic Exercise and Cognitive Training (ACT) in MCI
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT03313895-Jul 28, 2026
NCT ID
NCT03313895
Status
COMPLETED
Phase
Phase 2
Sponsor
Arizona State University
Executive brief
Investment-Ready Snapshot
The ACT trial, sponsored by Arizona State University, explores a non-pharmacological intervention combining aerobic exercise and cognitive training in older adults with amnestic mild cognitive impairment (aMCI). Given the high failure rate of drug trials for Alzheimer's disease, this study addresses a critical need for effective preventive strategies in high-risk populations. The trial's completion in July 2024 positions it to contribute valuable data to the growing market for cognitive health interventions, potentially influencing future therapeutic guidelines and creating opportunities for partnerships in behavioral health and wellness sectors. The results could also attract interest from investors focused on innovative approaches to neurodegenerative diseases.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03313895
Indication
Mild Cognitive Impairment
Modality
behavioral intervention
Target
Aerobic fitness, Alzheimer's disease signature cortical thickness, and functional connectivity in the default mode network (DMN)
Intervention
Aerobic & Cognitive Training (ACT), Cycling Only, Cognitive Training Only, Stretching and Mental Stimulating Activities
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.