NCT03628092Source recordAI-normalized
Laser Therapy for Vulvovaginal Symptoms in Breast Cancer Patients
The LAAVA2 trial, sponsored by Royal North Shore Hospital, explores the efficacy of fractional ablative CO2 laser therapy in alleviating vulvovaginal symptoms in breast cancer patients. This patient population is often underserved due to the side effects of cancer treatments, creating a niche market opportunity. If successful, this therapy could address a significant unmet need, potentially leading to a competitive advantage in the women's health segment. The trial's randomized, double-blind design enhances its credibility, which may facilitate future partnerships or licensing opportunities. The estimated enrollment of 70 participants suggests a focused study, but the overall status remains 'unknown,' indicating potential delays or challenges in recruitment.
AI analysis
Indication: Vulvovaginal Atrophy
Modality: medical device
Target: Ablative carbon dioxide laser therapy targeting vulvovaginal atrophy (VVA) and genitourinary syndrome of menopause (GSM) symptoms.
Sponsor: Royal North Shore Hospital
Source URL: ClinicalTrials.gov
Source updated: Mar 12, 2020
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Vulvovaginal Atrophy, Genitourinary Symptoms and Ill-Defined Conditions
Condition normalized: Vulvovaginal Atrophy, Genitourinary Symptoms and Ill-Defined Conditions
Modality raw: medical device
Modality normalized: medical device
Target raw: Ablative carbon dioxide laser therapy targeting vulvovaginal atrophy (VVA) and genitourinary syndrome of menopause (GSM) symptoms.
Target normalized: Ablative carbon dioxide laser therapy targeting vulvovaginal atrophy (VVA) and genitourinary syndrome of menopause (GSM) symptoms.
NCT05446584Source recordAI-normalized
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
The clinical trial, sponsored by the University of Texas Southwestern Medical Center, investigates the relationship between amnestic mild cognitive impairment (aMCI) and mild traumatic brain injury (mTBI) using HD-tDCS. Given the increasing prevalence of cognitive disorders in aging populations, this study addresses a significant unmet medical need. The findings could inform future therapeutic strategies and biomarker development, potentially positioning the sponsor as a leader in cognitive impairment research. The market for cognitive enhancement and neurostimulation devices is growing, with increasing interest from both pharmaceutical and medical device companies. Competitive implications include the potential for partnerships or acquisitions based on successful outcomes, particularly if the study identifies novel biomarkers or effective interventions.
AI analysis
Indication: Mild Cognitive Impairment
Modality: medical device
Target: High Definition Transcranial Direct Current Stimulation (HD-tDCS) targeting neural circuits associated with memory and cognitive function.
Sponsor: University of Texas Southwestern Medical Center
Source URL: ClinicalTrials.gov
Source updated: May 06, 2026
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder, Amnestic Mild Cognitive Impairment, Mild Traumatic Brain Injury, Concussion, Brain
Condition normalized: Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder, Amnestic Mild Cognitive Impairment, Mild Traumatic Brain Injury, Concussion, Brain
Modality raw: medical device
Modality normalized: medical device
Target raw: High Definition Transcranial Direct Current Stimulation (HD-tDCS) targeting neural circuits associated with memory and cognitive function.
Target normalized: High Definition Transcranial Direct Current Stimulation (HD-tDCS) targeting neural circuits associated with memory and cognitive function.
NCT05253534Source recordAI-normalized
Pilot Study to Evaluate Clinically the Short-Term Efficacy of GlaucoT Glaucoma Treatment Glasses in the Treatment of Primary Open-Angle Glaucoma (GlaucoT)
Glaucot Teknoloji Anonim Sirketi's GlaucoT glasses represent an innovative approach to treating POAG by utilizing flicker light therapy, which has shown promise in neuroprotection. Given the increasing prevalence of glaucoma, projected to affect over 60 million individuals globally, this device could address a significant unmet need in the market. The competitive landscape includes traditional IOP-lowering medications and surgical interventions, but GlaucoT's non-invasive, cost-effective solution may appeal to patients seeking alternatives. Successful outcomes could position Glaucot as a leader in glaucoma management, potentially leading to partnerships or licensing opportunities within the ophthalmic device sector.
AI analysis
Indication: Primary Open-Angle Glaucoma
Modality: medical device
Target: Flicker light therapy targeting neuroprotection and retinal ganglion cell preservation in primary open-angle glaucoma (POAG).
Sponsor: Glaucot Teknoloji Anonim Sirketi
Source URL: ClinicalTrials.gov
Source updated: Nov 18, 2024
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Primary Open-Angle Glaucoma
Condition normalized: Primary Open-Angle Glaucoma
Modality raw: medical device
Modality normalized: medical device
Target raw: Flicker light therapy targeting neuroprotection and retinal ganglion cell preservation in primary open-angle glaucoma (POAG).
Target normalized: Flicker light therapy targeting neuroprotection and retinal ganglion cell preservation in primary open-angle glaucoma (POAG).
NCT05287958Source recordAI-normalized
A Pilot Study on the Technical Feasibility of an Electrical Impedance Tomography Device for Quantitative Pulmonary Function Testing in ALS Patients
This pilot study, sponsored by Beth Israel Deaconess Medical Center, aims to evaluate the technical feasibility of an Electrical Impedance Tomography (EIT) device for noninvasive pulmonary function testing in patients with Amyotrophic Lateral Sclerosis (ALS). The study's completion indicates a potential advancement in pulmonary monitoring technologies, particularly for ALS patients who often experience respiratory complications. The market for respiratory monitoring devices is growing, driven by increasing prevalence of chronic respiratory diseases and the need for innovative, noninvasive diagnostic tools. Competitive implications include the potential for EIT to differentiate itself from traditional pulmonary function tests (PFTs) by offering real-time imaging and assessment. Diligence considerations should focus on regulatory pathways, reimbursement strategies, and the integration of EIT into existing clinical workflows.
AI analysis
Indication: ALS
Modality: medical device
Target: Electrical Impedance Tomography (EIT) for pulmonary function monitoring
Sponsor: Beth Israel Deaconess Medical Center
Source URL: ClinicalTrials.gov
Source updated: Apr 16, 2024
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: ALS
Condition normalized: ALS
Modality raw: medical device
Modality normalized: medical device
Target raw: Electrical Impedance Tomography (EIT) for pulmonary function monitoring
Target normalized: Electrical Impedance Tomography (EIT) for pulmonary function monitoring
NCT01605006Source recordAI-normalized
HDE Post-Approval Study (PAS) of NeuRx DPS for ALS
The NeuRx Diaphragm Pacing System (DPS) is positioned as a therapeutic intervention for patients with Amyotrophic Lateral Sclerosis (ALS) experiencing chronic hypoventilation. With a target enrollment of 60 participants, the study aims to assess the safety and probable benefits of the device over a two-year follow-up period. Given the increasing prevalence of ALS and the limited treatment options available, the NeuRx DPS addresses a significant unmet medical need in respiratory management for ALS patients. The competitive landscape includes traditional mechanical ventilation and other emerging therapies, but the NeuRx DPS offers a unique, less invasive alternative that could enhance patient quality of life. The successful demonstration of safety and efficacy could facilitate broader adoption and potential reimbursement pathways, enhancing market penetration. Diligence considerations should focus on regulatory compliance, post-market surveillance, and the evolving landscape of ALS treatment options.
AI analysis
Indication: Amyotrophic Lateral Sclerosis (ALS)
Modality: medical device
Target: Diaphragm muscle stimulation via phrenic nerve activation.
Sponsor: Synapse Biomedical
Source URL: ClinicalTrials.gov
Source updated: Mar 27, 2020
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Amyotrophic Lateral Sclerosis (ALS)
Condition normalized: Amyotrophic Lateral Sclerosis (ALS)
Modality raw: medical device
Modality normalized: medical device
Target raw: Diaphragm muscle stimulation via phrenic nerve activation.
Target normalized: Diaphragm muscle stimulation via phrenic nerve activation.
NCT05180838Source recordAI-normalized
Remote Data Capture of Elevated Temperature Data for Early Detection of Febrile Neutropenia in Patients With Hematologic Malignancies
The BioSticker device, developed by BioIntelliSense, Inc. and utilized in this clinical trial, represents a significant advancement in remote patient monitoring technology, particularly for patients undergoing treatment for hematologic malignancies. The potential for real-time alerts for febrile neutropenia (FN) could enhance patient safety and reduce hospitalizations, thereby improving overall treatment outcomes. The market for remote monitoring devices is expanding rapidly, driven by increasing demand for telehealth solutions and chronic disease management. The successful implementation of this technology could position BioIntelliSense favorably against competitors in the digital health space, particularly in oncology. Stakeholders should consider the implications of this technology on patient management protocols and the potential for integration into existing healthcare systems.
AI analysis
Indication: Hematologic Malignancy
Modality: medical device
Target: Remote monitoring of elevated temperature data for early detection of febrile neutropenia in patients with hematologic malignancies.
Sponsor: University of Colorado, Denver
Source URL: ClinicalTrials.gov
Source updated: Nov 21, 2024
Ingested: Jun 12, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Hematologic Malignancy
Condition normalized: Hematologic Malignancy
Modality raw: medical device
Modality normalized: medical device
Target raw: Remote monitoring of elevated temperature data for early detection of febrile neutropenia in patients with hematologic malignancies.
Target normalized: Remote monitoring of elevated temperature data for early detection of febrile neutropenia in patients with hematologic malignancies.
NCT00385983Source recordAI-normalized
Total Thyroidectomy With Harmonic Scalpel® Versus Standard Surgery. Open Multicentric Randomized Controlled Trial
Harmonic scalpel is a new surgical instrument. Its use has been recommended in patients submitted to total thyroidectomy. Few randomized controlled trials has been published. However they had small sample sizes, used intermediate outcomes and included different surgical procedures. Our objective is to asses the use of Harmonic scalpel in patients submitted to total thyroidectomy using surgical complications, operative time, drainage volume, postoperative pain, length of stay and costs as outcomes. Our hypothesis is that Harmonic scalpel decreases operative time,drainage volume, postoperative pain, length of stay and costs without increasing surgical complications
AI analysis
Indication: Thyroid Neoplasm
Modality: medical device
Target: Harmonic Scalpel
Sponsor: Brazilian Society of Head and Neck Surgery
Source URL: ClinicalTrials.gov
Source updated: Oct 11, 2006
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Thyroid Neoplasm, Goiter, Thyroid Nodule
Condition normalized: Thyroid Neoplasm, Goiter, Thyroid Nodule
Modality raw: medical device
Modality normalized: medical device
Target raw: Harmonic Scalpel
Target normalized: Harmonic Scalpel
NCT03166566Source recordAI-normalized
Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.
Purpose: To assess the feasibility of a surgical technique and present the preliminary safety results of a new glaucoma device devoid of a tube in painful blind eyes. Methods: Fifteen end-stage glaucomatous eyes without light perception vision were treated with a novel laminar drainage implant. Intraocular pressure was measured preoperatively and up to 24 months after surgery using a Goldmann applanation tonometer. A scale ranging from 0 to 10 was used to evaluate ocular pain. Conjunctival hyperemia, discharge, erosion or retraction, aqueous humor leakage, corneal edema, hyphema, anterior chamber cells and depth, dislocation of the implant, and filtering bleb height were assessed by slit-lamp biomicroscopy. Anterior segment optical coherence tomography was also assessed.
AI analysis
Indication: Glaucoma
Modality: medical device
Target: Laminar drainage implant surgery.
Sponsor: Federal University of Minas Gerais
Source URL: ClinicalTrials.gov
Source updated: May 25, 2017
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Glaucoma, Blindness, Acquired, End-Stage Glaucoma, Glaucoma Traumatic
Condition normalized: Glaucoma, Blindness, Acquired, End-Stage Glaucoma, Glaucoma Traumatic
Modality raw: medical device
Modality normalized: medical device
Target raw: Laminar drainage implant surgery.
Target normalized: Laminar drainage implant surgery.
NCT07219784Source recordAI-normalized
Abdominal Binders to Minimize Enteral Nutrition Disruptions for Preterm Infants On Non-Invasive Respiratory Support
The goal of this study is to learn if a foam belly strap, called "NeoBellyBand," can help with belly bloating, pauses in feedings, feeding success, and earlier discharge home for preterm infants who are requiring pressurized breathing support. Infants whose parents/ caregivers have consented to the study will be randomly chosen with a 50/50 chance of treatment with the NeoBellyBand or receiving standard NICU care. The main question it seeks to answer is if there are less interruptions to the feeding protocol for infants who have a NeoBellyBand placed on them compared with infants who do not. Infants on the treatment arm will have their bellies measured by trained personnel and have bands placed on them, which will be worn for most of the day while on breathing support with pressure.
AI analysis
Indication: Feeding Intolerance
Modality: medical device
Target: An abdominal binder
Sponsor: Albany Medical College
Source URL: ClinicalTrials.gov
Source updated: Oct 22, 2025
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Feeding Intolerance, Abdominal Distension
Condition normalized: Feeding Intolerance, Abdominal Distension
Modality raw: medical device
Modality normalized: medical device
Target raw: An abdominal binder
Target normalized: An abdominal binder
NCT02785445Source recordAI-normalized
A Comparative, Controlled Study to Evaluate the Clinical Accuracy and User Performance of the Dip Home-Based Dipstick Analyzer
The objectives of the Healthy.io Method Comparison and User Performance Study are: 1. To evaluate the performance of Dip.io Device in comparison to the ACON U500 Mission® U500 Urine Analyzer. 2. To evaluate the user performance of Dip.io Device under actual use conditions (home environment) based on a user questionnaire and rating scale.
AI analysis
Indication: Urinary Tract Infection
Modality: medical device
Target: Dip.io Home Based Dipstick Analyzer, ACON U500 Mission® U500 Urine Analyzer
Sponsor: Healthy.io Ltd.
Source URL: ClinicalTrials.gov
Source updated: Sep 11, 2017
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Urinary Tract Infection, Kidney Failure, Diabetes
Condition normalized: Urinary Tract Infection, Kidney Failure, Diabetes
Modality raw: medical device
Modality normalized: medical device
Target raw: Dip.io Home Based Dipstick Analyzer, ACON U500 Mission® U500 Urine Analyzer
Target normalized: Dip.io Home Based Dipstick Analyzer, ACON U500 Mission® U500 Urine Analyzer
NCT05350423Source recordAI-normalized
Use of Urinary Biomarkers to Quantify Degree of Renal, Parenchymal and Urothelial Damage During Ureteroscopy
This is an ongoing randomized controlled trial of patients undergoing URSLL with unilateral non-obstructing renal stones. Patients are randomized to undergo URSLL with either the TFL or Ho:YAG laser. Each patient's urine is collected immediately pre-op (V1), 1 hour post-op (V2), and 10 days post-op (POD#10, V3). Samples are analyzed by enzyme-linked immunosorbent assay (ELISA) for the following biomarkers: Kidney injury molecule-1 (KIM-1), Neutrophil gelatinase-associated lipocalin (NGAL), and β2-microglobulin (β2M), then normalized to urine creatinine.
AI analysis
Indication: Nephrolithiasis
Modality: medical device
Target: Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
Sponsor: Icahn School of Medicine at Mount Sinai
Source URL: ClinicalTrials.gov
Source updated: Dec 07, 2023
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Nephrolithiasis
Condition normalized: Nephrolithiasis
Modality raw: medical device
Modality normalized: medical device
Target raw: Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
Target normalized: Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
NCT01289548Source recordAI-normalized
Effect of Lower Limb Ischaemic Preconditioning on Renal Function in Patients Undergoing Living Donor Kidney Transplantation
The purpose of this study was to investigate whether lower limb ischaemic preconditioning can improve renal function in patients undergoing living donor kidney transplantation
AI analysis
Indication: Kidney Diseases
Modality: medical device
Target: remote ischaemic preconditioning
Sponsor: Huazhong University of Science and Technology
Source URL: ClinicalTrials.gov
Source updated: Sep 10, 2013
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Kidney Diseases, Kidney Failure, Chronic, Kidney Failure, Renal Insufficiency, Renal Insufficiency, Chronic, Urologic Diseases
Condition normalized: Kidney Diseases, Kidney Failure, Chronic, Kidney Failure, Renal Insufficiency, Renal Insufficiency, Chronic, Urologic Diseases
Modality raw: medical device
Modality normalized: medical device
Target raw: remote ischaemic preconditioning
Target normalized: remote ischaemic preconditioning
NCT07339098Source recordAI-normalized
A Prospective, Multicenter, Single-arm, Open-label, Non-randomized Exploratory Clinical Trial to Evaluate the Efficacy and Safety of Glomerular Filtration Rate (GFR-EPI) Using NEFRONIX in Patients With Chronic Kidney Disease (CKD)
Anasonic's NEFRONIX G-01 device is positioned in the emerging market of non-invasive therapies for chronic kidney disease, a condition affecting millions globally. The exploratory nature of this trial may provide initial efficacy and safety data, which could support further development and potential regulatory pathways. Given the increasing prevalence of CKD and the limitations of current treatment options, successful outcomes could lead to significant market opportunities. However, the competitive landscape includes established pharmaceutical interventions and emerging technologies, necessitating a thorough competitive analysis and strategic positioning. Diligence should focus on the robustness of trial design, potential regulatory hurdles, and reimbursement pathways.
AI analysis
Indication: Chronic Kidney Disease
Modality: medical device
Target: Ultrasound stimulation of renal tissue to potentially enhance glomerular filtration rate (GFR) in patients with chronic kidney disease (CKD).
Sponsor: Anasonic
Source URL: ClinicalTrials.gov
Source updated: Jan 15, 2026
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Chronic Kidney Disease
Condition normalized: Chronic Kidney Disease
Modality raw: medical device
Modality normalized: medical device
Target raw: Ultrasound stimulation of renal tissue to potentially enhance glomerular filtration rate (GFR) in patients with chronic kidney disease (CKD).
Target normalized: Ultrasound stimulation of renal tissue to potentially enhance glomerular filtration rate (GFR) in patients with chronic kidney disease (CKD).
NCT04193267Source recordAI-normalized
rTMS for the Improvement of Language Functioning in the Logopenic Variant of Primary Progressive Aphasia; a Feasibility and Tolerability Pilot Study
The purpose of this study is to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) - a form of non-invasive brain stimulation - to improve language functioning in individuals who have the logopenic variant of primary progressive aphasia (PPA-L) - a slowly progressive impairment of language, characterized by difficulties with word-finding, sentence repetition and sentence comprehension.
AI analysis
Indication: Logopenic Progressive Aphasia
Modality: medical device
Target: MagStim Rapid2 Transcranial Magnetic Simulation
Sponsor: University of Manitoba
Source URL: ClinicalTrials.gov
Source updated: Mar 22, 2021
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Logopenic Progressive Aphasia
Condition normalized: Logopenic Progressive Aphasia
Modality raw: medical device
Modality normalized: medical device
Target raw: MagStim Rapid2 Transcranial Magnetic Simulation
Target normalized: MagStim Rapid2 Transcranial Magnetic Simulation
NCT06641765Source recordAI-normalized
Continuous Glucose Monitoring in Haemodialysis and Peritoneal Dialysis Patients With Type 1 and Type 2 Diabetes
The primary objective of this multicenter, randomized controlled trial is to assess whether the intermittent or continuous use of continous glucose monitoring can enhance glycaemic control among dialysis patients with type 1 or type 2 diabetes, in comparison to the standard monitoring involving finger-prick glucose and HbA1c. Participants will be monitored for 9 months and randomly assigned to one of three groups: * Group 1, the control group, will undergo standard monitoring (using HbA1c and BGM) along with double-blinded CGM sessions at month 0, 3, 6, and 9. * Group 2 will have intermittent access to open CGM during the same time intervals. * Group 3 will have continuous access to open CGM throughout the entire duration of the study. During the study period, participants will have three consultations with an endocrinologist for adjustments in their glucose-lowering treatment. The goal is to compare markers of glycaemic control between the three groups. Secondary objectives include evaluating the impact on hypoglycaemia, quality of life, hospitals admissions and cardiovascular events.
AI analysis
Indication: Diabetes Mellitus, Type 2
Modality: medical device
Target: Continous Glucose Monitoring
Sponsor: Bo Feldt-Rasmussen
Source URL: ClinicalTrials.gov
Source updated: Feb 27, 2026
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Continuous Glucose Monitoring, Haemodialysis, Peritoneal Dialysis
Condition normalized: Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Continuous Glucose Monitoring, Haemodialysis, Peritoneal Dialysis
Modality raw: medical device
Modality normalized: medical device
Target raw: Continous Glucose Monitoring
Target normalized: Continous Glucose Monitoring
NCT00598663Source recordAI-normalized
Randomized, Cross Over, Controlled, Multi-centric Study to Assess Whether Type 1 Diabetic Patients in Sub-optimal Glycemic Control Can Improve Using the Continuous Glucose Values of the MiniMed Paradigm REAL-Time Insulin Pump System Versus the MiniMed Paradigm Insulin Pump
The SWITCH study, sponsored by Medtronic MiniMed, Inc., evaluates the efficacy of the MiniMed Paradigm REAL-Time Insulin Pump System with continuous glucose monitoring (CGM) versus the standard insulin pump with self-monitoring blood glucose (SMBG) in patients with Type 1 diabetes exhibiting sub-optimal glycemic control. Given the increasing prevalence of diabetes and the growing demand for advanced diabetes management technologies, this study positions Medtronic favorably within the competitive landscape of diabetes care devices. The results may enhance Medtronic's market share and reinforce its product offerings in the CGM space, particularly as healthcare providers and patients seek improved glycemic control solutions. Diligence should focus on the regulatory landscape and potential reimbursement pathways for CGM technologies.
AI analysis
Indication: Diabetes Mellitus, Type 1
Modality: medical device
Target: Continuous glucose monitoring in Type 1 diabetes management
Sponsor: Medtronic MiniMed, Inc.
Source URL: ClinicalTrials.gov
Source updated: Sep 16, 2019
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Diabetes Mellitus, Type 1
Condition normalized: Diabetes Mellitus, Type 1
Modality raw: medical device
Modality normalized: medical device
Target raw: Continuous glucose monitoring in Type 1 diabetes management
Target normalized: Continuous glucose monitoring in Type 1 diabetes management
NCT07352410Source recordAI-normalized
Safety and Early Clinical Performance of High-Purity Type I Collagen Augmentation in Arthroscopic Meniscal Repair: A Prospective Feasibility Study
This prospective, single-arm feasibility study evaluates the safety, procedural feasibility, and early clinical outcomes of High-Purity Type I Collagen used as an adjunct in arthroscopic meniscal repair. The study aims to generate preliminary clinical, functional, and imaging data to inform the design of a future randomized controlled trial.
AI analysis
Indication: Meniscus Tear
Modality: medical device
Target: High-Purity Type I Collagen
Sponsor: Adichunchanagiri Institute of Medical Sciences, B G Nagara
Source URL: ClinicalTrials.gov
Source updated: Apr 08, 2026
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Meniscus Tear, Knee Meniscus Injury, Meniscal Repair, Knee Arthroscopy (for Diagnostic or Therapy)
Condition normalized: Meniscus Tear, Knee Meniscus Injury, Meniscal Repair, Knee Arthroscopy (for Diagnostic or Therapy)
Modality raw: medical device
Modality normalized: medical device
Target raw: High-Purity Type I Collagen
Target normalized: High-Purity Type I Collagen
NCT04815564Source recordAI-normalized
Use of Clear Aligners for the Treatment of Dental Malocclusion in Individuals With Osteogenesis Imperfecta
Misalignment of teeth and jaws (also called malocclusion) is a common life altering problem facing many individuals with Osteogenesis Imperfecta (OI). The presence of Dentinogenesis Imperfecta in teeth of OI individuals makes the use of conventional orthodontics in the form of braces very challenging. Clear aligners are newer form of orthodontic treatment and is less invasive than braces. Therefore, the aim of our study is to evaluate the efficiency and safety of using Invisalign clear aligners for orthodontic treatment in individuals with Osteogenesis Imperfecta. We seek individual with Osteogenesis Imperfecta, with mild to moderate malocclusion and no prior history of orthodontic treatment. This study will be held at three sites - McGill University, University of California Los Angeles and National Institute of Dental and Craniofacial research. This study will for the first time, help define guidelines for safe and efficient orthodontic treatment using clear aligners in individuals with Osteogenesis Imperfecta. If successful, this approach can rapidly be implemented into clinical practice, as the Invisalign system is readily available to orthodontists.
AI analysis
Indication: Osteogenesis Imperfecta
Modality: medical device
Target: Invisalign
Sponsor: Baylor College of Medicine
Source URL: ClinicalTrials.gov
Source updated: Dec 03, 2025
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Osteogenesis Imperfecta
Condition normalized: Osteogenesis Imperfecta
Modality raw: medical device
Modality normalized: medical device
Target raw: Invisalign
Target normalized: Invisalign
NCT04231916Source recordAI-normalized
High Resolution Thermal Imaging to Identify Vertebral Fractures in Children and Young People With Osteogenesis Imperfecta
Brittle bone disease also known as osteogenesis imperfecta (OI) is characterised by a defect in the bone tissue that leads to recurrent fractures and significant bone deformities in children. These fractures include vertebral (spinal) fractures. As a result, child with OI require regular clinic surveillance that includes repeated xrays of the spine. in our pilot study the investigators plan to use a thermal imaging camera that can pick up changes in temperature to 0.03 degrees to determine whether the investigators can accurately identify vertebral fractures without the need for radiation. in the first part of the study the investigators will compare the thermal images from the camera with the xrays to see if the investigators can pick up the vertebral fractures seen on the xray picture. If this is possible, then the investigators will move on to phase 2 of the study which will investigate the ability of the thermal camera to pick up vertebral fractures without prior knowledge of where the fractures are located. If this approach is successful this will help us to develop a nonradiation, lowcost painless way of identifying vertebral fractures in children with OI.
AI analysis
Indication: Osteogenesis Imperfecta
Modality: medical device
Target: Thermal imaging device
Sponsor: Sheffield Children's NHS Foundation Trust
Source URL: ClinicalTrials.gov
Source updated: Jan 18, 2020
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Osteogenesis Imperfecta
Condition normalized: Osteogenesis Imperfecta
Modality raw: medical device
Modality normalized: medical device
Target raw: Thermal imaging device
Target normalized: Thermal imaging device
NCT02814591Source recordAI-normalized
Development of a Novel, Safe Method for the Non-invasive Assessment of Human Bone Quality, In Vivo, Using Spatially Offset Raman Spectroscopy
In this study spatially offset Raman spectroscopy (SORS), which allows the collection of Raman spectra through turbid media, is being applied to collect Raman spectra of bone. The principal aim to find ways to use Raman spectroscopy to assess bone quality in vivo.
AI analysis
Indication: Osteoarthritis
Modality: medical device
Target: spatially offset Raman spectrometer (SORS)
Sponsor: University College, London
Source URL: ClinicalTrials.gov
Source updated: Nov 23, 2022
Ingested: Jun 11, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Osteoarthritis, Osteoporosis, Osteogenesis Imperfecta, Rickets / Osteomalacia, Bone Infection
Condition normalized: Osteoarthritis, Osteoporosis, Osteogenesis Imperfecta, Rickets / Osteomalacia, Bone Infection
Modality raw: medical device
Modality normalized: medical device
Target raw: spatially offset Raman spectrometer (SORS)
Target normalized: spatially offset Raman spectrometer (SORS)
NCT02682030Source recordAI-normalized
Utilization of Pulmonary Clearance Devices in Amyotrophic Lateral Sclerosis
The investigator is examining the use of one airway clearance medical device compared to the use of two airway clearance medical devices together in patients with amyotrophic lateral sclerosis (ALS). More specifically, the investigator wants to know how effective the use of either a mechanical High Frequency Chest Compression (HFCC) device is on its own or the use of both a mechanical High Frequency Chest Compression (HFCC) device and Cough Assist together to maintain a healthy airway and clear secretions. The first device is a passive form of mechanical High Frequency Chest Compression (HFCC), which was designed to help clear the airway of mucus and other secretions through mechanical knocking of the chest area. The second device, called a Cough Assist, aids patients to clear mucus and secretions that they would otherwise be unable to clear with coughing. This study will enroll up to 20 people in total at CSMC.
AI analysis
Indication: Amyotrophic Lateral Sclerosis
Modality: medical device
Target: High Frequency Chest Compression Device (HFCC), Cough Assist
Sponsor: Cedars-Sinai Medical Center
Source URL: ClinicalTrials.gov
Source updated: Aug 25, 2020
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Amyotrophic Lateral Sclerosis
Condition normalized: Amyotrophic Lateral Sclerosis
Modality raw: medical device
Modality normalized: medical device
Target raw: High Frequency Chest Compression Device (HFCC), Cough Assist
Target normalized: High Frequency Chest Compression Device (HFCC), Cough Assist
NCT05161546Source recordAI-normalized
Study of Bipolar Disorders and Retinal Electrophysiological Markers
Study of Bipolar Disorders and Retinal Electrophysiological Markers is a NA clinical asset sponsored by Centre Psychothérapique de Nancy in Bipolar Disorder. SEO and diligence focus: EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments, Optical Coherence Tomography (OCT), endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Bipolar Disorder
Modality: medical device
Target: EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments, Optical Coherence Tomography (OCT)
Sponsor: Centre Psychothérapique de Nancy
Source URL: ClinicalTrials.gov
Source updated: Aug 22, 2024
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Bipolar Disorder
Condition normalized: Bipolar Disorder
Modality raw: medical device
Modality normalized: medical device
Target raw: EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments, Optical Coherence Tomography (OCT)
Target normalized: EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments, Optical Coherence Tomography (OCT)
NCT05734092Source recordAI-normalized
Investigating the Effectiveness of Low-Level Laser in Reducing Root Resorption of the Upper Incisors During Intrusion Movement Using Mini-Implants in Adult Patients With Deep Overbite: A Randomized Controlled Clinical Trial
This study aims to investigate the effectiveness of low-level laser in reducing the resorption of the roots of the upper incisors. Participants will be recruited from patients who will attend the Department of Orthodontics and Dentofacial Orthopaedics at Damascus University. The study sample will consist of 30 patients with a deep bite who will be randomly distributed equally into two groups, 15 patients in each group, average age: 22.37±3.38 years. Mini-implants will apply between the roots of the maxillary central and lateral incisor at both sides with a loading force of 40 g on each end by using a nickel-titanium spring extending from the head of the mini-implants to a wire welded to it with two hooks. A low-level laser (Ga-Al-As) will be used with 808 nm wavelength in continuous mode, 250 milli-Watt power output, 4 Joules/point energy density, 16 s per point in the experimental group. It will be applied on the day of intrusion, then on days 3,7, and 14 of the first month, and then every 15 days starting from the second month until the end of the intrusion. In addition to adjusting the force gauge every 4 weeks until the end of the intrusion stage and reaching normal coverage will be activated every 4 weeks in both groups until normal overbite was reached.
AI analysis
Indication: Deep Overbite
Modality: medical device
Target: Traditional orthodontic treatment, Low-Level Laser
Sponsor: Damascus University
Source URL: ClinicalTrials.gov
Source updated: Feb 17, 2023
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Deep Overbite
Condition normalized: Deep Overbite
Modality raw: medical device
Modality normalized: medical device
Target raw: Traditional orthodontic treatment, Low-Level Laser
Target normalized: Traditional orthodontic treatment, Low-Level Laser
NCT04392167Source recordAI-normalized
Advanced Angle-Resolved Low Coherence Interferometry (a/LCI) Systems for Improved Clinical Utility: An a/LCI-Optical Coherence Tomography (OCT) Pilot Study
This study will test a newly developed dual modality probe, including optical coherence tomography (OCT) and angle-resolved low-coherence interferometry (a/LCI), in the human esophagus to determine 1) whether adequate tissue contact can be attained by the probe to acquire high quality images, and 2) to identify if these images can discern whether the imaged tissue is squamous or Barrett's Esophagus (BE) epithelium. This pilot study will test the operating characteristics of the probe and collect data for further optimization of the a/LCI-OCT device.
AI analysis
Indication: Barrett Esophagus
Modality: medical device
Target: a/LCI-OCT imaging probe, esophageal biopsy
Sponsor: Duke University
Source URL: ClinicalTrials.gov
Source updated: Nov 28, 2023
Ingested: Jun 09, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Barrett Esophagus
Condition normalized: Barrett Esophagus
Modality raw: medical device
Modality normalized: medical device
Target raw: a/LCI-OCT imaging probe, esophageal biopsy
Target normalized: a/LCI-OCT imaging probe, esophageal biopsy
NCT05471687Source recordAI-normalized
Evaluation of the Functional Impact of Coronary Stenoses in Diabetics by Spectral CT
The optimal screening methods for coronary insufficiency, a frequent and pejorative complication in diabetics, are subject to debate, particularly in situations of silent myocardial ischemia. The contemporary strategy consists of pre-selecting asymptomatic patients at very high cardiovascular (CV) risk by performing a coronary calcium score. If this is found to be high \>300 AU (Agatston units), the patient is suspected of being at high risk of silent myocardial ischemia (SMI), and the assessment is completed to exclude the presence of coronary artery disease likely to benefit from revascularization. The complementary evaluation consists in evaluating the myocardial perfusion to judge the perfusion repercussions. The most common examination to date is myocardial scintigraphy, because stress tests are too frequently submaximal in diabetics. However, the reproducibility of scintigraphy is controversial and their sensitivity and specificity are debated in this indication. This problem is similar in stable symptomatic coronary diabetic patients for whom an indication for functional examinations is justified. The double-energy double-layer spectral scanner (SDEDC) could now become a relevant tool in this field, since it can combine not only anatomical data (identification of coronary stenosis) but also functional data (myocardial perfusion) during a stress protocol. thanks to the spectral images which make it possible to measure the tissue concentration of intramyocardial iodine downstream of the considered stenosis.
AI analysis
Indication: Coronary Stenosis
Modality: medical device
Target: dual-energy dual-layer spectral scanner, Stress protocol with adenosin during dual-energy dual-layer spectral scanner
Sponsor: Hospices Civils de Lyon
Source URL: ClinicalTrials.gov
Source updated: Jul 25, 2022
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Coronary Stenosis, Diabetic
Condition normalized: Coronary Stenosis, Diabetic
Modality raw: medical device
Modality normalized: medical device
Target raw: dual-energy dual-layer spectral scanner, Stress protocol with adenosin during dual-energy dual-layer spectral scanner
Target normalized: dual-energy dual-layer spectral scanner, Stress protocol with adenosin during dual-energy dual-layer spectral scanner
NCT01912092Source recordAI-normalized
A NON-CONTROLLED PROSPECTIVE COHORT STUDY OF THE USE OF ASKINA® CALGITROL® PASTE + STANDARD OF CARE ON MILDLY INFECTED, NON-ISCHAEMIC DIABETIC FOOT ULCERS
The purpose of this study is to assess the efficacy of Askina® Calgitrol® Paste in reducing local infection in subjects treated for mildly infected Diabetic Foot Ulcers (DFU) with Askina® Calgitrol® Paste.
AI analysis
Indication: Diabetic Foot Ulcer (DFU)
Modality: medical device
Target: Askina Calgitrol paste
Sponsor: BBraun Medical SAS
Source URL: ClinicalTrials.gov
Source updated: Jul 31, 2015
Ingested: Jun 08, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Diabetic Foot Ulcer (DFU)
Condition normalized: Diabetic Foot Ulcer (DFU)
Modality raw: medical device
Modality normalized: medical device
Target raw: Askina Calgitrol paste
Target normalized: Askina Calgitrol paste
NCT05107388Source recordAI-normalized
AAREN: Continuous Glucose Monitoring Profile Description Under Alpelisib treAtment in Patients With Advanced bREast Cancer
The purpose of this study is to describe the glycemic profile of postmenopausal women treated with alpelisib plus fulvestrant using a continuous blood sugar monitoring device (FreeStyle Libre Pro) over 14 days
AI analysis
Indication: Breast Cancer
Modality: medical device
Target: FreeStyle Libre Pro
Sponsor: Centre Hospitalier Universitaire de Besancon
Source URL: ClinicalTrials.gov
Source updated: Nov 04, 2021
Ingested: Jun 07, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Breast Cancer, Diabetes
Condition normalized: Breast Cancer, Diabetes
Modality raw: medical device
Modality normalized: medical device
Target raw: FreeStyle Libre Pro
Target normalized: FreeStyle Libre Pro
NCT04390997Source recordAI-normalized
Determination of the Levels of Lipocalin-2 and Semaphorin3A in Gingival Crevicular Fluid in Subjects With Different Periodontal Diseases
The aim of this clinical trial is to investigate the concentrations of Lipocalin-2 and Semaphorin 3A levels in gingival crevicular fluid in subjects with different periodontal diseases. At the same time for the periodontitis group; the purpose of this study is to analyze the correlation of these proteins with clinical parameters at the first and third months after the nonsurgical periodontal treatment.
AI analysis
Indication: Gingivitis
Modality: medical device
Target: Non-surgical Periodontal Treatment
Sponsor: Izmir Katip Celebi University
Source URL: ClinicalTrials.gov
Source updated: Feb 10, 2021
Ingested: Jun 05, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Gingivitis, Periodontitis, Periodontal Diseases
Condition normalized: Gingivitis, Periodontitis, Periodontal Diseases
Modality raw: medical device
Modality normalized: medical device
Target raw: Non-surgical Periodontal Treatment
Target normalized: Non-surgical Periodontal Treatment
NCT03057457Source recordAI-normalized
The NGAL Test™ As An Aid in the Risk Assessment for AKI Stage II and III in an Intensive Care Population
The NGAL TestTM is a particle-enhanced turbidimetric immunoassay for the quantitative determination of neutrophil gelatinase-associated lipocalin (NGAL) in human EDTA plasma for testing on automated clinical chemistry analyzer. The First Indication for Use: An NGAL test result above the assay cutoff as an aid in the risk assessment for the development of stage II or III acute kidney injury (AKI) within 1 day of patient assessment in patients in the intensive care unit (ICU) who are hypotensive (MAP\<70 mmHg) and/or receiving vasopressor support. Second Indication for Use: In patents with stage II or III AKI, NGAL measurement aids in the risk assessment of the development of persistent (≥2 days) stage 2 or 3 AKI. The Primary Objective for this clinical trial is to validate that the NGAL test using a cutoff of 140 ng/ml shows clinical performance in predicting the development of moderate or severe acute kidney injury within 1 day. The Secondary Objective is to validate that the NGAL test shows clinical performance in predicting persistent moderate or severe acute kidney injury during any contiguous 2 day interval. It is anticipated that up to 20 Clinical Sites in US will participate in the trial. The study sites will recruit consecutive patients meeting the inclusion and exclusion criteria who are admitted to hospital in an ICU or critical care setting. Patients will receive their clinical standard of care including standard laboratory and other testing as requested by each subject's physician.
AI analysis
Indication: Kidney Injury
Modality: medical device
Target: NGAL Test
Sponsor: BioPorto Diagnostics
Source URL: ClinicalTrials.gov
Source updated: Mar 31, 2017
Ingested: Jun 05, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Kidney Injury
Condition normalized: Kidney Injury
Modality raw: medical device
Modality normalized: medical device
Target raw: NGAL Test
Target normalized: NGAL Test
NCT02766010Source recordAI-normalized
A Comparative Clinical Study to Assess the Accuracy of TensorTip MTX, a Non Invasive Device for the Measurement of Physiological and Hematological Parameters
Cnoga Medical Ltd. conducted a comparative clinical trial to evaluate the accuracy of the TensorTip MTX device in measuring various physiological and hematological parameters against hospital reference devices. The study aimed to demonstrate the device's capability for non-invasive monitoring.
AI analysis
Indication: Blood Pressure
Modality: medical device
Target: Physiological and hematological parameters measurement
Sponsor: Cnoga Medical Ltd.
Source URL: ClinicalTrials.gov
Source updated: Jan 28, 2020
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Blood Pressure
Condition normalized: Blood Pressure
Modality raw: Blood Pressure
Modality normalized: medical device
Target raw: Physiological and hematological parameters measurement
Target normalized: Physiological and hematological parameters measurement
NCT05914818Source recordAI-normalized
Proof of Concept of Pediatric and Adolescent EXPLORER V2 Exoskeleton in Children With Neurological and Neuromuscular Disease
MarsiBionics is developing the EXPLORER V2 exoskeleton aimed at assisting children with neurological and neuromuscular diseases in their daily activities. This clinical trial assesses the usability and safety of the device in real-world settings, which could enhance rehabilitation outcomes and market acceptance.
AI analysis
Indication: Cerebral Palsy
Modality: medical device
Target: Pediatric and Adolescent EXPLORER V2 Exoskeleton
Sponsor: MarsiBionics
Source URL: ClinicalTrials.gov
Source updated: Nov 03, 2023
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Cerebral Palsy
Condition normalized: Cerebral Palsy
Modality raw: Cerebral Palsy
Modality normalized: medical device
Target raw: Pediatric and Adolescent EXPLORER V2 Exoskeleton
Target normalized: Pediatric and Adolescent EXPLORER V2 Exoskeleton
NCT07132892Source recordAI-normalized
Clinical Use of Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy- A Pilot Study
This pilot study aims to evaluate the use of a poly-4-hydroxybutyrate (P4HB) surgical mesh scaffold in rhytidectomy procedures. The study will assess tissue changes, mechanical strength, elasticity, and wound healing in a small cohort of healthy adults undergoing elective surgery.
AI analysis
Indication: Tissue Adhesion
Modality: medical device
Target: Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy
Sponsor: Jeffrey M. Kenkel
Source URL: ClinicalTrials.gov
Source updated: Jan 07, 2026
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Tissue Adhesion
Condition normalized: Tissue Adhesion
Modality raw: Tissue Adhesion
Modality normalized: medical device
Target raw: Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy
Target normalized: Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy
NCT03673488Source recordAI-normalized
Prospective Study to Evaluate Use of TephaFLEX™ Sling Implanted Via a Retropubic Mid-urethral Sling Procedure for Treatment of Women With Stress Urinary Incontinence
The study evaluates the safety and efficacy of the TephaFLEX sling, a bioresorbable device made from poly-4-hydroxybutyrate (P4HB), for treating stress urinary incontinence in women. The trial aims to establish the feasibility of using a non-permanent mesh as an alternative to traditional polypropylene slings, which are associated with complications.
AI analysis
Indication: Stress Urinary Incontinence
Modality: medical device
Target: Stress Urinary Incontinence
Sponsor: Pelvic Floor Research Foundation of South Africa
Source URL: ClinicalTrials.gov
Source updated: Sep 17, 2018
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Stress Urinary Incontinence
Condition normalized: Stress Urinary Incontinence
Modality raw: Stress Urinary Incontinence
Modality normalized: medical device
Target raw: Stress Urinary Incontinence
Target normalized: Stress Urinary Incontinence
NCT05945329Source recordAI-normalized
A Prospective, Randomized, Controlled, Multi-Center Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation
C. R. Bard is conducting a multi-center, randomized controlled trial to evaluate the safety and effectiveness of the GalaFLEX LITE™ Scaffold in reducing capsular contracture recurrence in breast augmentation patients. The study aims to enroll between 250 and 530 subjects and compares the scaffold's performance against standard surgical procedures.
AI analysis
Indication: Capsular Contracture Associated With Breast Implant
Modality: medical device
Target: Capsular Contracture After Breast Implant Augmentation
Sponsor: C. R. Bard
Source URL: ClinicalTrials.gov
Source updated: May 22, 2026
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Capsular Contracture Associated With Breast Implant
Condition normalized: Capsular Contracture Associated With Breast Implant
Modality raw: Capsular Contracture Associated With Breast Implant
Modality normalized: medical device
Target raw: Capsular Contracture After Breast Implant Augmentation
Target normalized: Capsular Contracture After Breast Implant Augmentation
NCT04195854Source recordAI-normalized
STARS-R Registry: A Retrospective Observational Registry Evaluating the Use of P4HB Scaffolds for Soft Tissue Support in Plastic And Reconstructive Surgery
The STARS-R Registry, sponsored by C. R. Bard and in collaboration with Tepha, Inc., is a completed observational study aimed at collecting real-world data on the use and safety of P4HB scaffolds in plastic and reconstructive surgery. The study enrolled 1,183 patients who underwent procedures involving P4HB since January 1, 2014.
AI analysis
Indication: Plastic Surgery
Modality: medical device
Target: P4HB Scaffold for Soft Tissue Support
Sponsor: C. R. Bard
Source URL: ClinicalTrials.gov
Source updated: Feb 04, 2022
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Plastic Surgery
Condition normalized: Plastic Surgery
Modality raw: Plastic Surgery
Modality normalized: medical device
Target raw: P4HB Scaffold for Soft Tissue Support
Target normalized: P4HB Scaffold for Soft Tissue Support
NCT03911700Source recordAI-normalized
Prospective, Multi-Center, Open-Label, Randomized, Controlled Trial of Phasix™ Mesh to Prevent Incisional Hernia Subsequent to Open Midline Laparotomy
The PREVENT trial evaluates the efficacy of Phasix™ Mesh in preventing incisional hernias post-open midline laparotomy compared to standard suture closure. The trial is sponsored by C. R. Bard and is currently recruiting participants across multiple sites in the U.S. and Europe.
AI analysis
Indication: Open Midline Laparotomy
Modality: medical device
Target: Incisional Hernia Prevention
Sponsor: C. R. Bard
Source URL: ClinicalTrials.gov
Source updated: Feb 25, 2026
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Open Midline Laparotomy
Condition normalized: Open Midline Laparotomy
Modality raw: Open Midline Laparotomy
Modality normalized: medical device
Target raw: Incisional Hernia Prevention
Target normalized: Incisional Hernia Prevention
NCT02720042Source recordAI-normalized
A Post-Market, Prospective, Multi-Center, Single-Arm Clinical Investigation of Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair
C. R. Bard conducted a clinical trial to assess the safety and performance of Phasix™ Mesh in treating VHWG Grade 3 midline hernias. The study enrolled 84 patients across 12 sites in Europe, with a focus on long-term outcomes over 24 months.
AI analysis
Indication: Hernia
Modality: medical device
Target: Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair
Sponsor: C. R. Bard
Source URL: ClinicalTrials.gov
Source updated: Sep 25, 2020
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Hernia
Condition normalized: Hernia
Modality raw: Hernia
Modality normalized: medical device
Target raw: Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair
Target normalized: Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair
NCT03446378Source recordAI-normalized
tDCS Guided by Interhemispheric Assimetry Level on Upper Limb Rehabilitation of Post Stroke Patients
This completed clinical trial investigated the efficacy of tDCS combined with physical therapy for upper limb rehabilitation in post-stroke patients. The study aimed to correlate cortical excitability with motor recovery, potentially leading to improved rehabilitation protocols.
AI analysis
Indication: Stroke
Modality: medical device
Target: Stroke rehabilitation using transcranial direct current stimulation (tDCS)
Sponsor: Universidade Federal de Pernambuco
Source URL: ClinicalTrials.gov
Source updated: May 06, 2020
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Stroke
Condition normalized: Stroke
Modality raw: Stroke
Modality normalized: medical device
Target raw: Stroke rehabilitation using transcranial direct current stimulation (tDCS)
Target normalized: Stroke rehabilitation using transcranial direct current stimulation (tDCS)
NCT00990665Source recordAI-normalized
Promote Q CRT-D and Quartet Left Ventricular Heart Lead Study
The Promote Q CRT-D and Quartet LV lead study, sponsored by Abbott Medical Devices, aimed to evaluate the safety and efficacy of a new cardiac resynchronization therapy device in patients with heart failure. The study enrolled 178 participants and was completed in July 2012.
AI analysis
Indication: Heart Failure
Modality: medical device
Target: Heart Failure
Sponsor: Abbott Medical Devices
Source URL: ClinicalTrials.gov
Source updated: Feb 27, 2019
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Heart Failure
Condition normalized: Heart Failure
Modality raw: Heart Failure
Modality normalized: medical device
Target raw: Heart Failure
Target normalized: Heart Failure
NCT02477202Source recordAI-normalized
Mirena® IUD's Effect on Fallopian Tube Fimbriae and Ovarian Cortical Inclusion Cyst Cell Proliferation
This study evaluates the effect of the Mirena® IUD on cell proliferation in the fallopian tube fimbriae, which may serve as a biomarker for reduced risk of invasive epithelial ovarian cancer (IEOC) in women aged 35-50 undergoing risk-reducing surgeries.
AI analysis
Indication: Epithelial Ovarian Cancer
Modality: medical device
Target: Epithelial Ovarian Cancer
Sponsor: Memorial Sloan Kettering Cancer Center
Source URL: ClinicalTrials.gov
Source updated: Oct 16, 2023
Ingested: May 30, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Epithelial Ovarian Cancer
Condition normalized: Epithelial Ovarian Cancer
Modality raw: Epithelial Ovarian Cancer
Modality normalized: medical device
Target raw: Epithelial Ovarian Cancer
Target normalized: Epithelial Ovarian Cancer
NCT02188966Source recordAI-normalized
Telemedical Solutions in Medical Emergencies, Advantages and Disadvantages for Patients, Healthcare Professionals, and Healthcare System. Study 4: Application of Geographical Information System Data in the Emergency Department, Effect on Trauma Team and Medical Emergency Team Wait - a Before and After Study
In the Emergency Department Regional Hospital Horsens a monitor will display Geographical Information System data (GIS data) for all ambulances with the hospital as final destination. The location, estimated time of arrival (ETA) and urgency code for the ambulances will be showed. Furthermore the patient's name, personal identification number and the primary message received by the emergency medical dispatch center resulting in ambulance dispatch will be displayed. This may enable the coordinating nurse to optimize timing of the ad hoc trauma team and medical emergency team activation. The teams are activated if the patient's condition is assessed to be of the highest urgency and/or severity - triage 1 or "red". The coordinating nurse makes this assessment on the basis of information from the ambulance personnel and makes the decision to activate the team and when to do it. In this study the investigators want to examine if the availability of GIS data in the emergency department results in reduced waiting time for the members of the trauma team and medical emergency team. The study will be conducted as a before and after study.
AI analysis
Indication: All Acutely Ill or Injured Patients
Modality: medical device
Target: Geographic Information System
Sponsor: University of Aarhus
Source URL: ClinicalTrials.gov
Source updated: Dec 09, 2015
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: All Acutely Ill or Injured Patients
Condition normalized: All Acutely Ill or Injured Patients
Modality raw: All Acutely Ill or Injured Patients
Modality normalized: medical device
Target raw: Geographic Information System
Target normalized: Geographic Information System
NCT01890954Source recordAI-normalized
Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in Adolescents
This clinical trial evaluated a closed-loop Control-to-Range (CTR) system, known as Diabetes Assistant (DiAs), in adolescents with type 1 diabetes. The study aimed to improve blood glucose control during instances of missed or insufficient insulin boluses. Conducted by the University of Virginia, it involved 17 participants aged 13-18 and utilized a crossover design to compare the DiAs system against usual care.
AI analysis
Indication: Diabetes Mellitus, Type 1
Modality: medical device
Target: Type 1 Diabetes Mellitus
Sponsor: University of Virginia
Source URL: ClinicalTrials.gov
Source updated: Sep 13, 2022
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Diabetes Mellitus, Type 1
Condition normalized: Diabetes Mellitus, Type 1
Modality raw: Diabetes Mellitus, Type 1
Modality normalized: medical device
Target raw: Type 1 Diabetes Mellitus
Target normalized: Type 1 Diabetes Mellitus
NCT03508050Source recordAI-normalized
Clamping the Double Lumen Tube : A Novel Technique to Optimize One-Lung Ventilation
This clinical trial investigates a novel technique for optimizing one-lung ventilation during thoracic surgery using a double-lumen tube (DLT). The study compares the efficacy of occluding the non-ventilated lung's lumen against the traditional method of leaving it open to ambient air. Conducted by Laval University, the trial enrolled 30 patients undergoing video-assisted thoracoscopic surgery (VATS).
AI analysis
Indication: One-lung Ventilation
Modality: medical device
Target: One-lung ventilation (OLV) optimization
Sponsor: Jean Bussières
Source URL: ClinicalTrials.gov
Source updated: Apr 27, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: One-lung Ventilation
Condition normalized: One-lung Ventilation
Modality raw: One-lung Ventilation
Modality normalized: medical device
Target raw: One-lung ventilation (OLV) optimization
Target normalized: One-lung ventilation (OLV) optimization
NCT02679287Source recordAI-normalized
Project Nightlight: Efficacy and System Acceptance of Dinner/Night vs. 24hr Closed Loop Control
The trial evaluated the efficacy of a Closed-Loop Control (CLC) system for managing blood glucose levels in individuals with Type 1 Diabetes. The study compared different configurations of the CLC system against standard sensor-augmented pump therapy, focusing on user acceptance and clinical outcomes.
AI analysis
Indication: Diabetes Mellitus, Type 1
Modality: medical device
Target: Type 1 Diabetes Mellitus
Sponsor: University of Virginia
Source URL: ClinicalTrials.gov
Source updated: Jun 09, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Diabetes Mellitus, Type 1
Condition normalized: Diabetes Mellitus, Type 1
Modality raw: Diabetes Mellitus, Type 1
Modality normalized: medical device
Target raw: Type 1 Diabetes Mellitus
Target normalized: Type 1 Diabetes Mellitus
NCT02604524Source recordAI-normalized
Reducing Risks and Improving Glucose Control During Extended Exercise in Youth With T1DM: The AP Ski Camp
This study evaluated the effectiveness of a Closed-Loop Control (CLC) system, also known as an Artificial Pancreas, in managing blood glucose levels during extended exercise in youth with T1DM. Conducted at a ski camp, the trial aimed to demonstrate the superiority of CLC over traditional Sensor-Augmented Pump (SAP) therapy.
AI analysis
Indication: Type 1 Diabetes Mellitus
Modality: medical device
Target: Type 1 Diabetes Mellitus (T1DM)
Sponsor: Daniel Chernavvsky, MD, CRC
Source URL: ClinicalTrials.gov
Source updated: Sep 19, 2018
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Type 1 Diabetes Mellitus
Condition normalized: Type 1 Diabetes Mellitus
Modality raw: Type 1 Diabetes Mellitus
Modality normalized: medical device
Target raw: Type 1 Diabetes Mellitus (T1DM)
Target normalized: Type 1 Diabetes Mellitus (T1DM)
NCT05410691Source recordAI-normalized
Handheld Ultrasound-guided Cannulation of Difficult Haemodialysis Arteriovenous Access by Renal Nurses - A Randomised Controlled Trial
This completed randomized controlled trial evaluated the effectiveness of handheld ultrasound (US) guidance for cannulation of difficult arteriovenous fistulas (AVF) or grafts (AVG) by renal nurses. The study aimed to improve cannulation success rates and reduce complications associated with vascular access in hemodialysis patients.
AI analysis
Indication: Hemodialysis Complication
Modality: medical device
Target: Difficult arteriovenous access in hemodialysis patients
Sponsor: National Healthcare Group, Singapore
Source URL: ClinicalTrials.gov
Source updated: Jun 08, 2022
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Hemodialysis Complication
Condition normalized: Hemodialysis Complication
Modality raw: Hemodialysis Complication
Modality normalized: medical device
Target raw: Difficult arteriovenous access in hemodialysis patients
Target normalized: Difficult arteriovenous access in hemodialysis patients
NCT01115335Source recordAI-normalized
Feasibility, Acceptability, and Safety of Neonatal Male Circumcision at the University Teaching Hospital in Lusaka, Zambia and in the Lusaka District in Zambia Using Gomco; Plastibell; and Mogen Methods
This study evaluates the feasibility, acceptability, and safety of neonatal male circumcision (NMC) in Lusaka, Zambia, using three surgical methods: Gomco, Plastibell, and Mogen. The research aims to inform the scale-up of NMC services as part of Zambia's HIV prevention strategy.
AI analysis
Indication: Neonatal Male Circumcision
Modality: medical device
Target: Neonatal Male Circumcision
Sponsor: University of Alabama at Birmingham
Source URL: ClinicalTrials.gov
Source updated: Jul 13, 2012
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Neonatal Male Circumcision
Condition normalized: Neonatal Male Circumcision
Modality raw: Neonatal Male Circumcision
Modality normalized: medical device
Target raw: Neonatal Male Circumcision
Target normalized: Neonatal Male Circumcision
NCT01397851Source recordAI-normalized
Stimulating Private Sector Malaria Control: The Outgrower Opportunity
The trial evaluated the profitability of providing insecticide-treated nets to smallholder farmers in Zambia, aiming to enhance cotton yields and reduce malaria prevalence. The intervention involved distributing nets for free to farmers, assessing its impact on agricultural productivity and financial outcomes for agribusiness.
AI analysis
Indication: Malaria
Modality: medical device
Target: Malaria control through insecticide-treated nets
Sponsor: PATH
Source URL: ClinicalTrials.gov
Source updated: Dec 15, 2023
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Malaria
Condition normalized: Malaria
Modality raw: Malaria
Modality normalized: medical device
Target raw: Malaria control through insecticide-treated nets
Target normalized: Malaria control through insecticide-treated nets
NCT01963923Source recordAI-normalized
Effectiveness of a Preoperative Pulmonary Rehabilitation Program in Exercise Tolerance and Quality of Life in Patients Awaiting Lung Resection by Video-assisted Thoracic Surgery
This clinical trial evaluated the effectiveness of a preoperative pulmonary rehabilitation program on exercise tolerance and quality of life in patients awaiting lung resection via video-assisted thoracic surgery. The study involved 40 patients, with a focus on improving outcomes through a structured rehabilitation program.
AI analysis
Indication: Lung Cancer
Modality: medical device
Target: Lung Cancer
Sponsor: Universidade da Coruña
Source URL: ClinicalTrials.gov
Source updated: May 01, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Lung Cancer
Condition normalized: Lung Cancer
Modality raw: Lung Cancer
Modality normalized: medical device
Target raw: Lung Cancer
Target normalized: Lung Cancer
NCT04208360Source recordAI-normalized
Clinical Evaluation of AI-aided Auscultation With Automatic Classification of Respiratory System Sounds
StethoMe is conducting a clinical trial to evaluate the effectiveness of its AI-driven stethoscope in identifying abnormal lung sounds in pediatric patients. The trial aims to compare the AI's performance against traditional physician auscultation, potentially positioning StethoMe's technology as a valuable tool in pediatric pulmonary diagnostics.
AI analysis
Indication: Wheezing
Modality: medical device
Target: AI-aided auscultation for respiratory sound classification
Sponsor: StethoMe
Source URL: ClinicalTrials.gov
Source updated: Oct 22, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Wheezing
Condition normalized: Wheezing
Modality raw: Wheezing
Modality normalized: medical device
Target raw: AI-aided auscultation for respiratory sound classification
Target normalized: AI-aided auscultation for respiratory sound classification
NCT04589923Source recordAI-normalized
The Measurement of VItal SIgns by Lifelight® Data Collect Software in comparisON to the Standard of Care in Acutely Unwell Patients - The VISION-Acute Study
The Measurement of VItal SIgns by Lifelight® Data Collect Software in comparisON to the Standard of Care in Acutely Unwell Patients - The VISION-Acute Study is a registry-stage clinical asset sponsored by Xim Limited in Hypertension, Hypoxia, Hypotension. SEO and diligence focus: Lifelight® Data Collect Blood Pressure Group, Lifelight® Data Collect Oxygen Saturation Group, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Hypertension
Modality: medical device
Target: Lifelight® Data Collect Blood Pressure Group, Lifelight® Data Collect Oxygen Saturation Group
Sponsor: Xim Limited
Source URL: ClinicalTrials.gov
Source updated: Jul 20, 2022
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Hypertension
Condition normalized: Hypertension
Modality raw: pulmonary arterial hypertension
Modality normalized: medical device
Target raw: Lifelight® Data Collect Blood Pressure Group, Lifelight® Data Collect Oxygen Saturation Group
Target normalized: Lifelight® Data Collect Blood Pressure Group, Lifelight® Data Collect Oxygen Saturation Group
NCT07522294Source recordAI-normalized
Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor Excision
Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor Excision is a NA clinical asset sponsored by Jeng-Fu You in Rectal Neoplasms, Rectal Cancer Patients, Rectal Benign Lesions. SEO and diligence focus: da Vinci SP Surgical System, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Rectal Neoplasms
Modality: medical device
Target: da Vinci SP Surgical System
Sponsor: Jeng-Fu You
Source URL: ClinicalTrials.gov
Source updated: Apr 17, 2026
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Rectal Neoplasms
Condition normalized: Rectal Neoplasms
Modality raw: colorectal cancer
Modality normalized: medical device
Target raw: da Vinci SP Surgical System
Target normalized: da Vinci SP Surgical System
NCT07398027Source recordAI-normalized
Post-Market Study of Transbronchial Cryo-assisted RFA During Robotic Assisted Bronchoscopy With Subsequent Surgical Resection (CRONOS-CH)
Post-Market Study of Transbronchial Cryo-assisted RFA During Robotic Assisted Bronchoscopy With Subsequent Surgical Resection (CRONOS-CH) is a NA clinical asset sponsored by Carolin Steinack in Lung Cancer. SEO and diligence focus: HybridTherm® System, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Lung Cancer
Modality: medical device
Target: HybridTherm® System
Sponsor: Carolin Steinack
Source URL: ClinicalTrials.gov
Source updated: Feb 09, 2026
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Lung Cancer
Condition normalized: Lung Cancer
Modality raw: non-small cell lung cancer
Modality normalized: medical device
Target raw: HybridTherm® System
Target normalized: HybridTherm® System
NCT07298486Source recordAI-normalized
Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALS: A Pilot Study
Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALS: A Pilot Study is a NA clinical asset sponsored by Nova Southeastern University in Amyotrophic Lateral Sclerosis (ALS). SEO and diligence focus: Robotic Glove Use, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Amyotrophic Lateral Sclerosis (ALS)
Modality: medical device
Target: Robotic Glove Use
Sponsor: Nova Southeastern University
Source URL: ClinicalTrials.gov
Source updated: Feb 25, 2026
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Amyotrophic Lateral Sclerosis (ALS)
Condition normalized: Amyotrophic Lateral Sclerosis (ALS)
Modality raw: ALS
Modality normalized: medical device
Target raw: Robotic Glove Use
Target normalized: Robotic Glove Use
NCT02599298Source recordAI-normalized
Sleep Study-Guided Multidisciplinary Therapy for Patients Presenting With Acute Coronary Syndrome
Sleep Study-Guided Multidisciplinary Therapy for Patients Presenting With Acute Coronary Syndrome is a NA clinical asset sponsored by National University of Singapore in Obstructive Sleep Apnea, Acute Coronary Syndrome. SEO and diligence focus: Continuous Positive Airway Therapy, Sleep-Study Guided Multidisciplinary Therapy, endpoint relevance, enrollment feasibility, competitive positioning, readout timing and IP durability.
AI analysis
Indication: Obstructive Sleep Apnea
Modality: medical device
Target: Continuous Positive Airway Therapy, Sleep-Study Guided Multidisciplinary Therapy
Sponsor: National University of Singapore
Source URL: ClinicalTrials.gov
Source updated: Nov 03, 2020
Ingested: May 23, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
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Condition raw: Obstructive Sleep Apnea
Condition normalized: Obstructive Sleep Apnea
Modality raw: heart failure obesity
Modality normalized: medical device
Target raw: Continuous Positive Airway Therapy, Sleep-Study Guided Multidisciplinary Therapy
Target normalized: Continuous Positive Airway Therapy, Sleep-Study Guided Multidisciplinary Therapy
NCT05784636Source recordAI-normalized
Comparative Study on the Effectiveness, Comfort and Compliance of High-flow Nasal Oxygen Therapy and Noninvasive Mechanical Ventilation BiPAP Mode in the Treatment of Hypoxemia Patients
Patients who met the inclusion criteria were included and signed an informed consent form, which complied with the requirements of the ethics committee of our unit. All subjects were inpatients. Subjects were randomized into two groups. patients in group A were first treated with HFNC on top of conventional treatment, and after 24 hours, patients were treated with non-invasive ventilator-assisted ventilation BiPAP mode until discharge. patients in group B were treated with a non-invasive ventilator on top of conventional treatment, and after 24 hours of treatment, patients were treated with HFNC until discharge. Patient information was collected during treatment.
AI analysis
Indication: Hypoxemia
Modality: medical device
Target: Non-invasive BiPAP ventilation, HFNC
Sponsor: Qilu Hospital of Shandong University
Source URL: ClinicalTrials.gov
Source updated: Mar 27, 2023
Ingested: May 21, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by modality_normalized: medical device
View original source fields
Condition raw: Hypoxemia
Condition normalized: Hypoxemia
Modality raw: medical device
Modality normalized: medical device
Target raw: Non-invasive BiPAP ventilation, HFNC
Target normalized: Non-invasive BiPAP ventilation, HFNC