The clinical trial, sponsored by the University Hospital of Montpellier, aimed to evaluate the efficacy of hypno-analgesia combined with EMLA patch versus standard care in reducing pain during lumbar punctures in patients with mild to moderate Alzheimer's disease. The trial was withdrawn due to internal organizational issues and dysfunction of study materials, indicating potential challenges in operational execution. The market for Alzheimer's diagnostics and associated procedures remains significant, with a growing focus on patient-centered care and non-pharmacological interventions. Companies investing in innovative pain management solutions may find opportunities in this space, particularly as the demand for improved patient experiences in invasive procedures increases.