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NCT02537977UNKNOWNanonymous

CD19-directed Chimeric Antigen Receptor T Cells Therapy in Relapsed/Refractory B Cell Malignancy

Sponsor

Source record

Shanghai Tongji Hospital, Tongji University School of Medicine

Phase

Source record

Phase 1/2

Modality

AI-normalized

cell therapy

Target

AI-normalized

CD19-directed Chimeric Antigen Receptor T Cells

Indication / condition

AI-normalized

Leukemia

Intervention

Source record

CD19-directed CAR-T cells

Source & freshness

Source record

NCT ID

NCT02537977

Original source

ClinicalTrials.gov

Source last updated

Dec 03, 2018

Ingested at

Jun 19, 2026

Internal sync

Jun 19, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT02537977

Title

CD19-directed Chimeric Antigen Receptor T Cells Therapy in Relapsed/Refractory B Cell Malignancy

Sponsor

Shanghai Tongji Hospital, Tongji University School of Medicine

Status

UNKNOWN

Phase

Phase 1/2

Condition raw

Leukemia, Lymphoma

Condition normalized

Leukemia, Lymphoma

Modality raw

cell therapy

Modality normalized

cell therapy

Target raw

CD19-directed Chimeric Antigen Receptor T Cells

Target normalized

CD19-directed Chimeric Antigen Receptor T Cells

Interventions

CD19-directed CAR-T cells

Public preview

Source record

The clinical trial sponsored by Shanghai Tongji Hospital focuses on the use of CD19-directed CAR T cell therapy for patients with relapsed/refractory B cell malignancies, specifically targeting those who have undergone multiple chemotherapy regimens without success. The market for CAR T cell therapies is rapidly expanding, particularly in the oncology sector, with significant competition from established players like Novartis and Gilead. The trial's focus on a patient population with limited treatment options positions it favorably for potential market entry, assuming positive safety and efficacy outcomes. Diligence should consider the regulatory landscape in China and potential for global expansion, as well as the need for robust manufacturing capabilities for CAR T cell products.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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