TrialSignal
Clinical trial intelligence report
CD19-directed Chimeric Antigen Receptor T Cells Therapy in Relapsed/Refractory B Cell Malignancy
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 19, 2026
NCT ID
NCT02537977
Status
UNKNOWN
Phase
Phase 1/2
Sponsor
Shanghai Tongji Hospital, Tongji University School of Medicine
Executive brief
Investment-Ready Snapshot
The clinical trial sponsored by Shanghai Tongji Hospital focuses on the use of CD19-directed CAR T cell therapy for patients with relapsed/refractory B cell malignancies, specifically targeting those who have undergone multiple chemotherapy regimens without success. The market for CAR T cell therapies is rapidly expanding, particularly in the oncology sector, with significant competition from established players like Novartis and Gilead. The trial's focus on a patient population with limited treatment options positions it favorably for potential market entry, assuming positive safety and efficacy outcomes. Diligence should consider the regulatory landscape in China and potential for global expansion, as well as the need for robust manufacturing capabilities for CAR T cell products.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02537977
Indication
Leukemia
Modality
cell therapy
Target
CD19-directed Chimeric Antigen Receptor T Cells
Intervention
CD19-directed CAR-T cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.