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cd19 directed chimeric antigen receptor t cells clinical trial intelligence

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target

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normalized field

NCT02537977
Source recordAI-normalized

CD19-directed Chimeric Antigen Receptor T Cells Therapy in Relapsed/Refractory B Cell Malignancy

The clinical trial sponsored by Shanghai Tongji Hospital focuses on the use of CD19-directed CAR T cell therapy for patients with relapsed/refractory B cell malignancies, specifically targeting those who have undergone multiple chemotherapy regimens without success. The market for CAR T cell therapies is rapidly expanding, particularly in the oncology sector, with significant competition from established players like Novartis and Gilead. The trial's focus on a patient population with limited treatment options positions it favorably for potential market entry, assuming positive safety and efficacy outcomes. Diligence should consider the regulatory landscape in China and potential for global expansion, as well as the need for robust manufacturing capabilities for CAR T cell products.

AI analysis

Indication: Leukemia

Modality: cell therapy

Target: CD19-directed Chimeric Antigen Receptor T Cells

Sponsor: Shanghai Tongji Hospital, Tongji University School of Medicine

Source URL: ClinicalTrials.gov

Source updated: Dec 03, 2018

Ingested: Jun 19, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: CD19-directed Chimeric Antigen Receptor T Cells

View original source fields

Condition raw: Leukemia, Lymphoma

Condition normalized: Leukemia, Lymphoma

Modality raw: cell therapy

Modality normalized: cell therapy

Target raw: CD19-directed Chimeric Antigen Receptor T Cells

Target normalized: CD19-directed Chimeric Antigen Receptor T Cells

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