CD19-directed Chimeric Antigen Receptor T Cells Therapy in Relapsed/Refractory B Cell Malignancy
The clinical trial sponsored by Shanghai Tongji Hospital focuses on the use of CD19-directed CAR T cell therapy for patients with relapsed/refractory B cell malignancies, specifically targeting those who have undergone multiple chemotherapy regimens without success. The market for CAR T cell therapies is rapidly expanding, particularly in the oncology sector, with significant competition from established players like Novartis and Gilead. The trial's focus on a patient population with limited treatment options positions it favorably for potential market entry, assuming positive safety and efficacy outcomes. Diligence should consider the regulatory landscape in China and potential for global expansion, as well as the need for robust manufacturing capabilities for CAR T cell products.
Indication: Leukemia
Modality: cell therapy
Target: CD19-directed Chimeric Antigen Receptor T Cells
Sponsor: Shanghai Tongji Hospital, Tongji University School of Medicine
Source URL: ClinicalTrials.gov
Source updated: Dec 03, 2018
Ingested: Jun 19, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: CD19-directed Chimeric Antigen Receptor T Cells
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Condition raw: Leukemia, Lymphoma
Condition normalized: Leukemia, Lymphoma
Modality raw: cell therapy
Modality normalized: cell therapy
Target raw: CD19-directed Chimeric Antigen Receptor T Cells
Target normalized: CD19-directed Chimeric Antigen Receptor T Cells