Services

Clinical intelligence engagements shaped around the decision.

TrialSign engagements are scoped around a specific biotech decision: an asset, target, indication, competitor set, licensing question or investment diligence need. Not every module is included in every engagement. The evidence plan is defined by the decision question.

Questions supported

The work begins with the question being decided.

  1. How strong is the clinical position of this asset?
  2. Which endpoint, comparator or population assumptions matter most?
  3. Where does the published evidence stop supporting the thesis?
  4. Which competitor, regulatory or patent signals should change the diligence plan?

Scope and evidence plan

What is reviewed is agreed before work begins.

Scope, timing and fee are agreed after the decision question, inclusion criteria, exclusion criteria, source plan, data cutoff and review depth are defined.

01Decision question
02Evidence plan
03Source collection
04Normalization
05Critical appraisal
06Human review
07Deliverables

Analytical modules

A modular analysis plan, not a fixed package.

Clinical trial landscape

Endpoint and comparator assessment

Population segmentation

Scientific publication appraisal

Target and mechanism context

Regulatory evidence

Company and competitive landscape

Preliminary patent research

Risk and uncertainty assessment

Strategic synthesis

Review and discussion

The deliverable is discussed, not just delivered.

The client receives the agreed materials: usually an Executive Decision Book for leadership and a Scientific Evidence Dossier for technical review. A Private Intelligence Room is included only where the project requires collaborative review or continuing access.

What is not included

Medical, legal, regulatory, patent or investment advice.

Unscoped self-service access to a database.

Automatic conclusions where source evidence is incomplete.

Confidential-material review before appropriate arrangements are agreed.

Confidential or unpublished materials should be shared only after the appropriate confidentiality arrangements are agreed.

Next step

Bring the decision question, not a prepared search strategy.

Share the asset, target, indication or diligence question. TrialSign will identify the information needed to define a proportionate evidence plan.

Discuss a Diligence Question