A Phase 2A Multicentre, Randomised, Double Blind, Placebo-Controlled, Parallel-Group Safety and Tolerability Study of PQ912 in Subjects With Early Alzheimer's Disease
Vivoryon Therapeutics N.V. is advancing PQ912, a glutaminyl cyclase inhibitor, in the treatment of early Alzheimer's disease, specifically targeting Mild Cognitive Impairment (MCI) and mild dementia due to Alzheimer's Disease (AD). The global Alzheimer's disease therapeutics market is projected to grow significantly, driven by increasing prevalence and demand for effective treatments. PQ912's unique mechanism of action positions it competitively against existing therapies, particularly in a landscape where disease-modifying treatments are scarce. The completion of this Phase 2A trial provides critical data that may enhance investor confidence and attract potential partnerships or acquisition interest, especially if preliminary efficacy results are favorable.
Indication: Alzheimer's Disease
Modality: small molecule
Target: Glutaminyl cyclase (QC) inhibition
Sponsor: Vivoryon Therapeutics N.V.
Source URL: ClinicalTrials.gov
Source updated: Detailed source ingestion pending
Ingested: Jul 21, 2026
Model: trialsignal-ai-v1
Validation: validated
Matched by target_normalized: Glutaminyl cyclase (QC) inhibition
View original source fields
Condition raw: Alzheimer's Disease
Condition normalized: Alzheimer's Disease
Modality raw: small molecule
Modality normalized: small molecule
Target raw: Glutaminyl cyclase (QC) inhibition
Target normalized: Glutaminyl cyclase (QC) inhibition