TrialSignal
Clinical trial intelligence report
A Phase 2A Multicentre, Randomised, Double Blind, Placebo-Controlled, Parallel-Group Safety and Tolerability Study of PQ912 in Subjects With Early Alzheimer's Disease
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT02389413-Jul 28, 2026
NCT ID
NCT02389413
Status
COMPLETED
Phase
Phase 2A
Sponsor
Vivoryon Therapeutics N.V.
Executive brief
Investment-Ready Snapshot
Vivoryon Therapeutics N.V. is advancing PQ912, a glutaminyl cyclase inhibitor, in the treatment of early Alzheimer's disease, specifically targeting Mild Cognitive Impairment (MCI) and mild dementia due to Alzheimer's Disease (AD). The global Alzheimer's disease therapeutics market is projected to grow significantly, driven by increasing prevalence and demand for effective treatments. PQ912's unique mechanism of action positions it competitively against existing therapies, particularly in a landscape where disease-modifying treatments are scarce. The completion of this Phase 2A trial provides critical data that may enhance investor confidence and attract potential partnerships or acquisition interest, especially if preliminary efficacy results are favorable.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02389413
Indication
Alzheimer's Disease
Modality
small molecule
Target
Glutaminyl cyclase (QC) inhibition
Intervention
PQ912 oral, Placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.