target directory

bcma b cell maturation antigen cd19 cd22 cd79 clinical trial intelligence

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target

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normalized field

NCT04665076
Source recordAI-normalized

Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell Tumors

Hebei Senlang Biotechnology Inc., Ltd. is conducting a multicenter clinical trial to evaluate the safety and efficacy of CAR-T cell therapy in patients with relapsed/refractory plasma cell tumors. The trial targets a niche but critical segment of the oncology market, specifically addressing patients who have limited treatment options due to the refractory nature of their disease. The competitive landscape includes established CAR-T therapies, such as those targeting BCMA, which have shown promise in similar patient populations. Successful outcomes could position Hebei Senlang favorably within the CAR-T market, potentially leading to partnerships or acquisitions, especially given the increasing interest in innovative therapies for hematological malignancies. However, the trial's non-randomized, single-arm design may limit the robustness of comparative efficacy claims against existing therapies.

AI analysis

Indication: Plasma Cell Tumors

Modality: cell therapy

Target: BCMA (B-cell maturation antigen), CD19, CD22, CD79

Sponsor: Hebei Senlang Biotechnology Inc., Ltd.

Source URL: ClinicalTrials.gov

Source updated: Dec 11, 2020

Ingested: Jun 12, 2026

Model: trialsignal-ai-v1

Validation: validated

Matched by target_normalized: BCMA (B-cell maturation antigen), CD19, CD22, CD79

View original source fields

Condition raw: Plasma Cell Tumors

Condition normalized: Plasma Cell Tumors

Modality raw: cell therapy

Modality normalized: cell therapy

Target raw: BCMA (B-cell maturation antigen), CD19, CD22, CD79

Target normalized: BCMA (B-cell maturation antigen), CD19, CD22, CD79

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