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NCT04665076UNKNOWNanonymous

Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell Tumors

Sponsor

Source record

Hebei Senlang Biotechnology Inc., Ltd.

Phase

Source record

Not Applicable

Modality

AI-normalized

cell therapy

Target

AI-normalized

BCMA (B-cell maturation antigen), CD19, CD22, CD79

Indication / condition

AI-normalized

Plasma Cell Tumors

Intervention

Source record

Auto CAR-T, Cyclophosphamide,Fludarabine, Leukapheresis

Source & freshness

Source record

NCT ID

NCT04665076

Original source

ClinicalTrials.gov

Source last updated

Dec 11, 2020

Ingested at

Jun 12, 2026

Internal sync

Jun 12, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT04665076

Title

Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell Tumors

Sponsor

Hebei Senlang Biotechnology Inc., Ltd.

Status

UNKNOWN

Phase

Not Applicable

Condition raw

Plasma Cell Tumors

Condition normalized

Plasma Cell Tumors

Modality raw

cell therapy

Modality normalized

cell therapy

Target raw

BCMA (B-cell maturation antigen), CD19, CD22, CD79

Target normalized

BCMA (B-cell maturation antigen), CD19, CD22, CD79

Interventions

Auto CAR-T, Cyclophosphamide,Fludarabine, Leukapheresis

Public preview

Source record

Hebei Senlang Biotechnology Inc., Ltd. is conducting a multicenter clinical trial to evaluate the safety and efficacy of CAR-T cell therapy in patients with relapsed/refractory plasma cell tumors. The trial targets a niche but critical segment of the oncology market, specifically addressing patients who have limited treatment options due to the refractory nature of their disease. The competitive landscape includes established CAR-T therapies, such as those targeting BCMA, which have shown promise in similar patient populations. Successful outcomes could position Hebei Senlang favorably within the CAR-T market, potentially leading to partnerships or acquisitions, especially given the increasing interest in innovative therapies for hematological malignancies. However, the trial's non-randomized, single-arm design may limit the robustness of comparative efficacy claims against existing therapies.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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