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Clinical trial intelligence report
Multi-center, Open Label, Randomized Trial Comparing Single Versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia (BMT CTN #0501)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT00412360-Jul 28, 2026
NCT ID
NCT00412360
Status
COMPLETED
Phase
Phase 3
Sponsor
Medical College of Wisconsin
Executive brief
Investment-Ready Snapshot
The trial, sponsored by the Medical College of Wisconsin, investigates the efficacy of single versus double umbilical cord blood transplantation in pediatric patients with high-risk leukemia and myelodysplasia. Given the increasing prevalence of hematologic malignancies in children and the potential for improved outcomes with double UCB transplants, this study could significantly impact treatment protocols and market dynamics in pediatric oncology. Successful results may enhance the competitive positioning of UCB transplantation as a standard of care, potentially influencing reimbursement policies and attracting interest from biopharma companies focused on hematological therapies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT00412360
Indication
Acute Myelogenous Leukemia
Modality
protein therapy
Target
Umbilical Cord Blood (UCB) Transplantation
Intervention
Single Umbilical Cord Blood Unit Transplant, Double Umbilical Cord Blood Unit Transplant, Total Body Irradiation, Cyclophosphamide, Fludarabine, Cyclosporine A, Mycophenolate Mofetil
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.