TrialSignal
Clinical trial intelligence report
Open Label Positron Emission Tomography Study With [18F]AZD4694 and [11C]AZD2184, Candidate Radioligands for AB Amyloid, to Determine and Compare in Vivo Brain Uptake and Distribution in Healthy Volunteers and Patients With Alzheimer's Disease
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT00838877-Jul 28, 2026
NCT ID
NCT00838877
Status
COMPLETED
Phase
Phase 1
Sponsor
AstraZeneca
Executive brief
Investment-Ready Snapshot
The clinical trial conducted by AstraZeneca evaluates two candidate radioligands, [18F]AZD4694 and [11C]AZD2184, for their efficacy in imaging Aβ amyloid depositions in Alzheimer's Disease (AD) patients. Given the increasing prevalence of AD and the growing demand for effective diagnostic tools, successful outcomes from this study could position AstraZeneca favorably in the neuroimaging market. The trial's completion in 2009 suggests that AstraZeneca may have already progressed to subsequent phases or alternative studies, potentially enhancing their portfolio in Alzheimer's diagnostics. The competitive landscape includes other pharmaceutical companies and imaging technology firms focusing on similar radioligands, necessitating continuous monitoring of advancements in this space.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT00838877
Indication
Alzheimer's Disease
Modality
radioligand therapy
Target
Aβ amyloid depositions in the human brain
Intervention
radioligand [18F]AZD4694, radioligand [11C]AZD2184
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.