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Clinical trial intelligence report
Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Pregnant Women in the Democratic Republic of Congo
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT01916954-Jun 24, 2026
NCT ID
NCT01916954
Status
COMPLETED
Phase
Phase 3
Sponsor
University of Oxford
Executive brief
Investment-Ready Snapshot
The trial compares two regimens of artemether-lumefantrine (ALN) for treating uncomplicated Plasmodium falciparum malaria in pregnant women, a demographic often excluded from clinical studies. Given the high morbidity and mortality associated with malaria in pregnancy, successful outcomes could enhance ALN's market position in regions with high malaria prevalence, particularly in sub-Saharan Africa. The findings may lead to revised dosing recommendations, potentially increasing the drug's usage and market share. The study's completion may also attract interest from public health organizations and NGOs focused on maternal and child health, further driving demand. However, the competitive landscape includes other antimalarial therapies, and the efficacy of ALN in this specific population will be critical for its commercial viability.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01916954
Indication
Malaria
Modality
small molecule
Target
Plasmodium falciparum malaria parasites
Intervention
3-day artemether-lumefantrine, 5-day artemether-lumefantrine
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.