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NCT07115238RECRUITINGanonymous

A Phase 3, Multicenter Study to Evaluate the Efficacy and Safety of PET Visual Assessment Using XTR006 Injection for Detection of Brain Neurofibrillary Tangles (NFTs) in Elderly Subjects

Sponsor

Source record

Sinotau Pharmaceutical Group

Phase

Source record

Phase 3

Modality

AI-normalized

small molecule

Target

AI-normalized

Neurofibrillary tangles (NFTs) in the brain, associated with Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI).

Indication / condition

AI-normalized

Alzheimer Disease

Intervention

Source record

XTR006

Source & freshness

Source record

NCT ID

NCT07115238

Original source

ClinicalTrials.gov

Source last updated

Aug 11, 2025

Ingested at

Jun 19, 2026

Internal sync

Jun 19, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT07115238

Title

A Phase 3, Multicenter Study to Evaluate the Efficacy and Safety of PET Visual Assessment Using XTR006 Injection for Detection of Brain Neurofibrillary Tangles (NFTs) in Elderly Subjects

Sponsor

Sinotau Pharmaceutical Group

Status

RECRUITING

Phase

Phase 3

Condition raw

Alzheimer Disease, Neurofibrillary Tangle

Condition normalized

Alzheimer Disease, Neurofibrillary Tangle

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Neurofibrillary tangles (NFTs) in the brain, associated with Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI).

Target normalized

Neurofibrillary tangles (NFTs) in the brain, associated with Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI).

Interventions

XTR006

Public preview

Source record

Sinotau Pharmaceutical Group is conducting a Phase 3 clinical trial to evaluate the efficacy and safety of XTR006, a PET radiopharmaceutical, for detecting neurofibrillary tangles in elderly subjects. The trial targets a significant unmet need in the Alzheimer's disease market, where accurate diagnostic tools are crucial for early intervention. The trial's success could position XTR006 as a valuable diagnostic tool, potentially leading to partnerships with healthcare providers and integration into clinical practice. Given the increasing prevalence of Alzheimer's and related dementias, the market opportunity is substantial, with a growing demand for innovative diagnostic solutions. Competitive analysis indicates that while there are existing imaging agents, XTR006 may offer improved sensitivity and specificity, enhancing its market positioning.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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