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NCT04928456COMPLETEDanonymous

Augmentation of Immune Response to COVID-19 mRNA Vaccination Through Osteopathic Manipulative Treatment Including Lymphatic Pumps

Sponsor

Source record

Western University of Health Sciences

Phase

Source record

Completed

Modality

AI-normalized

RNA therapy

Target

AI-normalized

Immune response enhancement via Osteopathic Manipulative Treatment (OMT) in conjunction with mRNA COVID-19 vaccination.

Indication / condition

AI-normalized

Covid19

Intervention

Source record

Osteopathic Manipulative Treatment (OMT)

Source & freshness

Source record

NCT ID

NCT04928456

Original source

ClinicalTrials.gov

Source last updated

Apr 26, 2024

Ingested at

Jun 19, 2026

Internal sync

Jun 19, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT04928456

Title

Augmentation of Immune Response to COVID-19 mRNA Vaccination Through Osteopathic Manipulative Treatment Including Lymphatic Pumps

Sponsor

Western University of Health Sciences

Status

COMPLETED

Phase

Completed

Condition raw

Covid19

Condition normalized

Covid19

Modality raw

RNA therapy

Modality normalized

RNA therapy

Target raw

Immune response enhancement via Osteopathic Manipulative Treatment (OMT) in conjunction with mRNA COVID-19 vaccination.

Target normalized

Immune response enhancement via Osteopathic Manipulative Treatment (OMT) in conjunction with mRNA COVID-19 vaccination.

Interventions

Osteopathic Manipulative Treatment (OMT)

Public preview

Source record

The trial conducted by Western University of Health Sciences aimed to evaluate the potential of OMT to augment the immune response to mRNA COVID-19 vaccines. Given the ongoing concerns regarding vaccine efficacy against emerging variants and waning immunity, a successful outcome could position OMT as a complementary therapy in vaccination protocols, potentially expanding market opportunities in immunotherapy and preventive healthcare. The study's findings may attract interest from vaccine manufacturers and healthcare providers seeking to enhance vaccine effectiveness, thereby influencing competitive dynamics in the immunization landscape. Additionally, the collaboration with various osteopathic organizations may facilitate broader acceptance and integration of OMT in clinical practice, enhancing the commercial viability of this approach.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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