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NCT03563326UNKNOWNanonymous

Clinical Trial of Intraperitoneal CAR-T Cells Infusion for the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis

Sponsor

Source record

Jian-Kun Hu

Phase

Source record

Phase 1

Modality

AI-normalized

cell therapy

Target

AI-normalized

Epithelial Cell Adhesion Molecule (EpCAM)

Indication / condition

AI-normalized

Neoplasm, Stomach

Intervention

Source record

CAR-T cells targeting EpCAM, Chemotherapy

Source & freshness

Source record

NCT ID

NCT03563326

Original source

ClinicalTrials.gov

Source last updated

Sep 17, 2018

Ingested at

Jun 19, 2026

Internal sync

Jun 19, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT03563326

Title

Clinical Trial of Intraperitoneal CAR-T Cells Infusion for the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis

Sponsor

Jian-Kun Hu

Status

UNKNOWN

Phase

Phase 1

Condition raw

Neoplasm, Stomach, Metastases, Neoplasm, Neoplasm Seeding

Condition normalized

Neoplasm, Stomach, Metastases, Neoplasm, Neoplasm Seeding

Modality raw

cell therapy

Modality normalized

cell therapy

Target raw

Epithelial Cell Adhesion Molecule (EpCAM)

Target normalized

Epithelial Cell Adhesion Molecule (EpCAM)

Interventions

CAR-T cells targeting EpCAM, Chemotherapy

Public preview

Source record

The clinical trial, sponsored by Jian-Kun Hu at West China Hospital, aims to evaluate the safety and efficacy of EpCAM-targeted CAR-T cell therapy for advanced gastric cancer with peritoneal metastasis. Given the high incidence and mortality rates of gastric cancer, particularly in China, this trial addresses a significant unmet medical need. If successful, the therapy could provide a novel treatment option in a market with limited effective therapies for this patient population. The competitive landscape includes traditional chemotherapy and emerging immunotherapies, necessitating thorough diligence on regulatory pathways and potential partnerships for commercialization.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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