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NCT00711789UNKNOWNanonymous

A Pilot Crossover Randomised Controlled Trial of Angiotensin II in Critically Ill Patients With Severe Sepsis and Acute Renal Failure

Sponsor

Source record

Austin Health

Phase

Source record

PHASE2

Modality

AI-normalized

small molecule

Target

AI-normalized

Angiotensin II, Saline placebo

Indication / condition

AI-normalized

Acute Renal Failure

Intervention

Source record

Angiotensin II, Saline placebo

Source & freshness

Source record

NCT ID

NCT00711789

Original source

ClinicalTrials.gov

Source last updated

Jun 23, 2011

Ingested at

Jun 18, 2026

Internal sync

Jun 18, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT00711789

Title

A Pilot Crossover Randomised Controlled Trial of Angiotensin II in Critically Ill Patients With Severe Sepsis and Acute Renal Failure

Sponsor

Austin Health

Status

UNKNOWN

Phase

PHASE2

Condition raw

Acute Renal Failure, Sepsis, Septic Shock

Condition normalized

Acute Renal Failure, Sepsis, Septic Shock

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Angiotensin II, Saline placebo

Target normalized

Angiotensin II, Saline placebo

Interventions

Angiotensin II, Saline placebo

Public preview

Source record

The purpose of this study is to determine the effect of a systemic infusion of angiotensin II on haemodynamics and urine output in critically ill patients with severe sepsis/septic shock and acute renal failure.

It will also help determine the feasibility of conducting a definitive and adequately powered randomised controlled trial of angiotensin II in such patients that would assess mortality and need for renal replacement therapy as endpoints.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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