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An Open-label, Safety and Tolerability Extension Trial Assessing Repeated Dosing of Anti-KIR (1-7F9) Human Monoclonal Antibody in Patients With Acute Myeloid Leukaemia
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 18, 2026
NCT ID
NCT01256073
Status
COMPLETED
Phase
Phase 1
Sponsor
Innate Pharma
Executive brief
Investment-Ready Snapshot
Innate Pharma's IPH2101 (Anti-KIR (1-7F9)) is positioned within a niche market targeting elderly patients with Acute Myeloid Leukemia (AML) who are in complete remission but are ineligible for allogeneic stem-cell transplantation. The focus on safety and tolerability in this population addresses a significant unmet need, as treatment options are limited for this demographic. The competitive landscape includes other immunotherapeutic approaches for AML, but IPH2101's unique mechanism targeting KIR may provide a differentiated profile. The successful completion of this trial could enhance Innate Pharma's portfolio and attract potential partnerships or acquisition interest, particularly from larger oncology-focused biopharma companies seeking to expand their hematological malignancy offerings.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01256073
Indication
Acute Myeloid Leukemia
Modality
monoclonal antibody
Target
Killer Immunoglobulin-like Receptor (KIR) on Natural Killer (NK) cells
Intervention
IPH2101
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.