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NCT00630851COMPLETEDanonymous

A Six-month, Multicenter, Double-blind, Parallel, Placebo-controlled Study of the Effect on Global/Behavioural/ADL Functions and Tolerability of Aricept in Patients Wtih Severe Alzheimer's Disease Living in an Assisted Care Facility

Sponsor

Source record

Pfizer

Phase

Source record

Phase 3

Modality

AI-normalized

small molecule

Target

AI-normalized

Acetylcholinesterase inhibition (Donepezil/Aricept)

Indication / condition

AI-normalized

Alzheimer Disease

Intervention

Source record

Donepezil (Aricept), Placebo

Source & freshness

Source record

NCT ID

NCT00630851

Original source

ClinicalTrials.gov

Source last updated

Mar 05, 2015

Ingested at

Jun 18, 2026

Internal sync

Jun 18, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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View original source fields

NCT ID

NCT00630851

Title

A Six-month, Multicenter, Double-blind, Parallel, Placebo-controlled Study of the Effect on Global/Behavioural/ADL Functions and Tolerability of Aricept in Patients Wtih Severe Alzheimer's Disease Living in an Assisted Care Facility

Sponsor

Pfizer

Status

COMPLETED

Phase

Phase 3

Condition raw

Alzheimer Disease

Condition normalized

Alzheimer Disease

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Acetylcholinesterase inhibition (Donepezil/Aricept)

Target normalized

Acetylcholinesterase inhibition (Donepezil/Aricept)

Interventions

Donepezil (Aricept), Placebo

Public preview

Source record

The clinical trial evaluates the efficacy and safety of Donepezil (Aricept) in patients with severe Alzheimer's disease residing in assisted care facilities. Given the increasing prevalence of Alzheimer's disease and the limited treatment options available, this study targets a significant market segment. If successful, Aricept could reinforce Pfizer's position in the Alzheimer's treatment landscape, particularly in the nursing home demographic, which is often underserved. Competitive analysis indicates that while several alternatives exist, Donepezil remains a well-established treatment, and positive trial outcomes could enhance its market share against emerging therapies. Diligence considerations should focus on the long-term safety profile and potential regulatory hurdles for expanded indications.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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