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An Exploratory Clinical Study of the Safety and Efficacy of NKG2D Chimeric Antigen Receptor NK Cell Injections for the Treatment of Efractory Recurrent Multiple Myeloma
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 18, 2026
NCT ID
NCT06379451
Status
UNKNOWN
Phase
Early Phase 1
Sponsor
Changzhou No.2 People's Hospital
Executive brief
Investment-Ready Snapshot
The exploratory study sponsored by Changzhou No.2 People's Hospital aims to evaluate the safety and efficacy of NKG2D CAR-NK cell injections for treating refractory recurrent multiple myeloma (MM). Given the increasing incidence of MM and the limitations of current therapies, including CAR-T cell therapy, this approach may address a significant unmet medical need. The market for MM therapies is expanding, with a focus on innovative cell therapies. If successful, this asset could position itself as a competitive alternative to existing treatments, particularly in patients with relapsed/refractory disease who are not candidates for traditional therapies. The trial's outcomes could influence future development strategies and partnerships in the immunotherapy landscape.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06379451
Indication
Multiple Myeloma
Modality
small molecule
Target
NKG2D receptor on NK cells, targeting NKG2D ligands (NKG2DL) expressed on tumor cells.
Intervention
NKG2D Chimeric Antigen Receptor NK Cell Injection
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.