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NCT05360186RECRUITINGanonymous

The Efficacy and Safety of a New Cross-linked Hyaluronan Gel to Prevent Adhesion After Ultrasound-guided Manual Vacuum Aspiration (USG-MVA): A Prospective Randomized Controlled Trial

Sponsor

Source record

Chinese University of Hong Kong

Phase

Source record

Not Applicable (NA)

Modality

AI-normalized

medical device

Target

AI-normalized

Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).

Indication / condition

AI-normalized

First Trimester Abortion

Intervention

Source record

MateRegen® gel (BioRegen)

Source & freshness

Source record

NCT ID

NCT05360186

Original source

ClinicalTrials.gov

Source last updated

Aug 13, 2025

Ingested at

Jun 17, 2026

Internal sync

Jun 17, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT05360186

Title

The Efficacy and Safety of a New Cross-linked Hyaluronan Gel to Prevent Adhesion After Ultrasound-guided Manual Vacuum Aspiration (USG-MVA): A Prospective Randomized Controlled Trial

Sponsor

Chinese University of Hong Kong

Status

RECRUITING

Phase

Not Applicable (NA)

Condition raw

First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia

Condition normalized

First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia

Modality raw

medical device

Modality normalized

medical device

Target raw

Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).

Target normalized

Cross-linked Hyaluronan Gel (NCH gel) aimed at preventing intrauterine adhesions (IUA) post-Manual Vacuum Aspiration (MVA).

Interventions

MateRegen® gel (BioRegen)

Public preview

Source record

The trial, sponsored by the Chinese University of Hong Kong, evaluates the efficacy of NCH gel in preventing intrauterine adhesions following ultrasound-guided manual vacuum aspiration for first-trimester miscarriage. If successful, this product could address a significant unmet need in women's reproductive health, particularly in reducing complications associated with IUA. The market for adhesion prevention products is growing, with increasing awareness and demand for minimally invasive solutions in gynecological procedures. Competitive analysis indicates that while there are existing products in the market, the unique formulation and application of NCH gel may provide a differentiated offering. Diligence should focus on regulatory pathways, potential partnerships for commercialization, and the landscape of existing patents related to hyaluronan-based products.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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