TrialSignal
Clinical trial intelligence report
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study to Assess the Efficacy, Safety and Tolerability of Aleglitazar Plus Metformin Combination Therapy Compared With Placebo Plus Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 17, 2026
NCT ID
NCT01691846
Status
COMPLETED
Phase
Phase 3
Sponsor
Hoffmann-La Roche
Executive brief
Investment-Ready Snapshot
Aleglitazar, in combination with metformin, is being evaluated for its efficacy in patients with inadequately controlled Type 2 Diabetes Mellitus (T2D) on metformin monotherapy. The market for diabetes treatments is substantial, with a growing demand for combination therapies that enhance glycemic control and address associated metabolic issues. If successful, aleglitazar could position Hoffmann-La Roche favorably against competitors in the diabetes space, particularly those offering single-agent therapies or less effective combinations. The completion of this Phase 3 trial could facilitate regulatory approval and subsequent market entry, enhancing Roche's portfolio in diabetes management.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01691846
Indication
Diabetes Mellitus Type 2
Modality
small molecule
Target
Dual PPAR agonist (PPAR-alpha and PPAR-gamma)
Intervention
aleglitazar+metformin, placebo+metformin
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.