TrialSignal
Clinical trial intelligence report
A Clinical Research of CD123-Targeted CAR-T in Myeloid Malignancies
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 17, 2026
NCT ID
NCT02937103
Status
UNKNOWN
Phase
Phase 1/2
Sponsor
Southwest Hospital, China
Executive brief
Investment-Ready Snapshot
The clinical trial, sponsored by Southwest Hospital in China, focuses on the therapeutic potential of CD123-targeted CAR-T cells for treating myeloid malignancies, which currently lack effective treatment options for relapsed or refractory cases. The trial aims to address a significant unmet medical need in the oncology market, particularly for patients ineligible for allogeneic stem cell transplantation. Given the promising results seen with CD19-targeted CAR-T therapies in B cell malignancies, this trial could position the sponsor as a key player in the CAR-T space for myeloid cancers, potentially leading to lucrative partnerships or acquisition interest from larger biopharmaceutical companies. The estimated enrollment of 45 patients and the focus on safety and efficacy will be critical for future commercialization strategies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02937103
Indication
Leukemia
Modality
cell therapy
Target
CD123-targeted chimeric antigen receptor (CAR) T cells
Intervention
Anti-CD123-CAR-transduced T cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.