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NCT05508061COMPLETEDanonymous

Fully Automated Glycemic Control With Ultrarapid Insulin in a Bihormonal Closed Loop System in Patients With Type 1 Diabetes

Sponsor

Source record

Inreda Diabetic B.V.

Phase

Source record

Not Applicable

Modality

AI-normalized

combination therapy

Target

AI-normalized

Insulin receptor (IR) and glucagon receptor (GCGR) for glycemic control in Type 1 Diabetes.

Indication / condition

AI-normalized

Type 1 Diabetes

Intervention

Source record

Insulin Lispro Cartridge [Lyumjev], Insulin Lispro Cartridge

Source & freshness

Source record

NCT ID

NCT05508061

Original source

ClinicalTrials.gov

Source last updated

Feb 17, 2026

Ingested at

Jun 17, 2026

Internal sync

Jun 17, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT05508061

Title

Fully Automated Glycemic Control With Ultrarapid Insulin in a Bihormonal Closed Loop System in Patients With Type 1 Diabetes

Sponsor

Inreda Diabetic B.V.

Status

COMPLETED

Phase

Not Applicable

Condition raw

Type 1 Diabetes

Condition normalized

Type 1 Diabetes

Modality raw

combination therapy

Modality normalized

combination therapy

Target raw

Insulin receptor (IR) and glucagon receptor (GCGR) for glycemic control in Type 1 Diabetes.

Target normalized

Insulin receptor (IR) and glucagon receptor (GCGR) for glycemic control in Type 1 Diabetes.

Interventions

Insulin Lispro Cartridge [Lyumjev], Insulin Lispro Cartridge

Public preview

Source record

Inreda Diabetic B.V. is investigating the efficacy of Lyumjev, an ultrarapid insulin, in a bihormonal closed-loop system designed for automated glucose regulation in Type 1 Diabetes patients. This multicenter, open-label, randomized, cross-over trial aims to demonstrate that Lyumjev can outperform standard Humalog therapy in terms of glycemic control, specifically by reducing the time spent above target glucose levels. The successful demonstration of Lyumjev's efficacy could position Inreda favorably in the competitive landscape of diabetes management technologies, particularly as the demand for advanced insulin delivery systems continues to grow. The results may also enhance the commercial viability of Lyumjev in combination with Inreda's artificial pancreas technology, potentially leading to expanded market opportunities and partnerships. Given the increasing prevalence of diabetes, the asset could attract significant interest from investors and collaborators focused on innovative diabetes solutions.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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