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Clinical trial intelligence report
The Effect of Opiate Blockade With Naltrexone on Counterregulatory Mechanisms in Hypoglycemia
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 17, 2026
NCT ID
NCT01462227
Status
COMPLETED
Phase
Not Applicable
Sponsor
Yale University
Executive brief
Investment-Ready Snapshot
The study investigates the use of naltrexone, a known opioid receptor antagonist, to enhance recovery from hypoglycemia in patients with type 1 diabetes. Given the lack of current therapeutic options for managing hypoglycemia recovery, a successful outcome could position naltrexone as a novel treatment in the diabetes care market. The potential to address a significant unmet medical need could attract interest from pharmaceutical companies specializing in diabetes management. However, the competitive landscape includes ongoing research into alternative therapies for hypoglycemia, necessitating thorough diligence on market entry strategies and potential partnerships.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01462227
Indication
Hypoglycemia
Modality
small molecule
Target
Opiate receptors (specifically mu-opioid receptors) involved in counterregulatory hormone release during hypoglycemia.
Intervention
Naltrexone High Dose, Naltrexone Low Dose
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.