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Clinical trial intelligence report
Energy Expenditure and Brown Adipose Tissue in Amyotrophic Lateral Sclerosis
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 17, 2026
NCT ID
NCT03150290
Status
COMPLETED
Phase
NA
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Executive brief
Investment-Ready Snapshot
Weight loss is a common phenomenon in ALS. During the course of the disease, difficulty in swallowing and mastication can be responsible for a decrease in caloric intake and thus for weight loss. However, significant weight loss can also be observed in patients with no feeding difficulties. About half of ALS patients have an increase in their resting energy consumption, but the origin of this "hypermetabolism" remains unknown. "Brown" fat is specialized in the production of heat. Unlike "white" fat that stores excess caloric intakes, brown fat consumes energy. In humans, brown fat has long been considered as absent in adults. However, recent imaging techniques have been able to detect brown fat deposits in some adult subjects. The aim of this study is thus to determine the role of brown fat on energy consumption in Amyotrophic Lateral Sclerosis.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03150290
Indication
Amyotrophic Lateral Sclerosis
Modality
medical device
Target
Indirect Calorimetry., 18-FDG-PET
Intervention
Indirect Calorimetry., 18-FDG-PET
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.