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An Open-Label, Randomized Naturalistic Study to Evaluate the Incidence of Hypoglycemia Comparing Sitagliptin With Sulfonylurea Treatment in Patients With Type 2 Diabetes During Ramadan Fasting
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT01131182
Status
COMPLETED
Phase
Phase 4
Sponsor
Merck Sharp & Dohme LLC
Executive brief
Investment-Ready Snapshot
The clinical trial conducted by Merck Sharp & Dohme LLC evaluates the safety and efficacy of sitagliptin compared to sulfonylureas in managing hypoglycemia during Ramadan fasting in patients with Type 2 Diabetes Mellitus. Given the significant Muslim population that observes Ramadan, this study addresses a critical need in diabetes management, potentially expanding sitagliptin's market share in regions with high fasting prevalence. The results may enhance Merck's competitive positioning against other diabetes therapies, particularly sulfonylureas, which are widely used but carry a higher risk of hypoglycemia. The findings could also inform marketing strategies and educational initiatives aimed at healthcare providers and patients in these demographics.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01131182
Indication
Type 2 Diabetes Mellitus (T2DM)
Modality
small molecule
Target
Dipeptidyl peptidase-4 (DPP-4)
Intervention
Sitagliptin phosphate, Comparator: Sulfonylurea, Metformin
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.