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NCT01131182COMPLETEDanonymous

An Open-Label, Randomized Naturalistic Study to Evaluate the Incidence of Hypoglycemia Comparing Sitagliptin With Sulfonylurea Treatment in Patients With Type 2 Diabetes During Ramadan Fasting

Sponsor

Source record

Merck Sharp & Dohme LLC

Phase

Source record

Phase 4

Modality

AI-normalized

small molecule

Target

AI-normalized

Dipeptidyl peptidase-4 (DPP-4)

Indication / condition

AI-normalized

Type 2 Diabetes Mellitus (T2DM)

Intervention

Source record

Sitagliptin phosphate, Comparator: Sulfonylurea, Metformin

Source & freshness

Source record

NCT ID

NCT01131182

Original source

ClinicalTrials.gov

Source last updated

Sep 21, 2022

Ingested at

Jun 16, 2026

Internal sync

Jun 16, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT01131182

Title

An Open-Label, Randomized Naturalistic Study to Evaluate the Incidence of Hypoglycemia Comparing Sitagliptin With Sulfonylurea Treatment in Patients With Type 2 Diabetes During Ramadan Fasting

Sponsor

Merck Sharp & Dohme LLC

Status

COMPLETED

Phase

Phase 4

Condition raw

Type 2 Diabetes Mellitus (T2DM)

Condition normalized

Type 2 Diabetes Mellitus (T2DM)

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Dipeptidyl peptidase-4 (DPP-4)

Target normalized

Dipeptidyl peptidase-4 (DPP-4)

Interventions

Sitagliptin phosphate, Comparator: Sulfonylurea, Metformin

Public preview

Source record

The clinical trial conducted by Merck Sharp & Dohme LLC evaluates the safety and efficacy of sitagliptin compared to sulfonylureas in managing hypoglycemia during Ramadan fasting in patients with Type 2 Diabetes Mellitus. Given the significant Muslim population that observes Ramadan, this study addresses a critical need in diabetes management, potentially expanding sitagliptin's market share in regions with high fasting prevalence. The results may enhance Merck's competitive positioning against other diabetes therapies, particularly sulfonylureas, which are widely used but carry a higher risk of hypoglycemia. The findings could also inform marketing strategies and educational initiatives aimed at healthcare providers and patients in these demographics.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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