TrialSignal
Clinical trial intelligence report
Multicenter, One-arm, Phase II Clinical Study of Decitabine Combined With Unrelated Cord Blood Transplantation for the Treatment of Acute Myeloid Leukemia (AML) in the Elderly
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT03913312
Status
UNKNOWN
Phase
Phase 2
Sponsor
Ruijin Hospital
Executive brief
Investment-Ready Snapshot
This Phase II trial, sponsored by Ruijin Hospital, aims to evaluate the efficacy and safety of a novel treatment regimen combining decitabine and cytarabine with unrelated cord blood transplantation in elderly patients with AML. Given the aging population and the high unmet medical need in this demographic, successful outcomes could position this therapy favorably in a competitive market. The trial's focus on a vulnerable patient population (aged 60-75) highlights potential for market differentiation. However, the absence of FDA regulation may limit immediate commercial viability in certain markets. The results could attract interest from larger biopharmaceutical companies for potential partnerships or acquisitions, especially if the regimen demonstrates superior outcomes compared to traditional therapies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03913312
Indication
Acute Myeloid Leukemia
Modality
protein therapy
Target
Decitabine (DAC) and cytarabine in combination with unrelated cord blood transplantation for the treatment of acute myeloid leukemia (AML) in elderly patients.
Intervention
Unrelated cord blood
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.