Report workspace

Add to folder
NCT00301574COMPLETEDanonymous

Placebo-Controlled, Double-Blind Study of Galantamine (R113675) in the Treatment of Alzheimer's Disease.

Sponsor

Source record

Janssen Pharmaceutical K.K.

Phase

Source record

Phase 3

Modality

AI-normalized

small molecule

Target

AI-normalized

Cholinergic system modulation via inhibition of acetylcholinesterase, enhancing cholinergic neurotransmission.

Indication / condition

AI-normalized

Alzheimer Disease

Intervention

Source record

galantamine

Source & freshness

Source record

NCT ID

NCT00301574

Original source

ClinicalTrials.gov

Source last updated

May 17, 2011

Ingested at

Jun 16, 2026

Internal sync

Jun 16, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT00301574

Title

Placebo-Controlled, Double-Blind Study of Galantamine (R113675) in the Treatment of Alzheimer's Disease.

Sponsor

Janssen Pharmaceutical K.K.

Status

COMPLETED

Phase

Phase 3

Condition raw

Alzheimer Disease

Condition normalized

Alzheimer Disease

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Cholinergic system modulation via inhibition of acetylcholinesterase, enhancing cholinergic neurotransmission.

Target normalized

Cholinergic system modulation via inhibition of acetylcholinesterase, enhancing cholinergic neurotransmission.

Interventions

galantamine

Public preview

Source record

Galantamine, a cholinesterase inhibitor, is being evaluated for its efficacy and safety in treating Alzheimer's disease. The market for Alzheimer's therapeutics is substantial, with increasing prevalence due to aging populations. The competitive landscape includes other cholinesterase inhibitors and novel mechanisms targeting amyloid and tau pathology. Successful outcomes could position Janssen favorably in a market with significant unmet needs, particularly for patients with moderate Alzheimer's disease. Diligence should focus on the drug's safety profile, potential market access hurdles, and existing competitive products.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account

Create a free account first, then unlock a single report, buy credits or subscribe.