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NCT03799913UNKNOWNanonymous

A Clinical Trial of MESO-CAR T Cells Therapy for Relapsed and Refractory Ovarian Cancer

Sponsor

Source record

Zhejiang University

Phase

Source record

Early Phase 1

Modality

AI-normalized

cell therapy

Target

AI-normalized

Anti-MESO antigen receptors (CARs) T cell therapy targeting mesothelin-expressing tumors.

Indication / condition

AI-normalized

Ovarian Cancer

Intervention

Source record

anti-MESO CAR-T cells, Fludarabine, Cyclophosphamide

Source & freshness

Source record

NCT ID

NCT03799913

Original source

ClinicalTrials.gov

Source last updated

Apr 10, 2019

Ingested at

Jun 16, 2026

Internal sync

Jun 16, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT03799913

Title

A Clinical Trial of MESO-CAR T Cells Therapy for Relapsed and Refractory Ovarian Cancer

Sponsor

Zhejiang University

Status

UNKNOWN

Phase

Early Phase 1

Condition raw

Ovarian Cancer

Condition normalized

Ovarian Cancer

Modality raw

cell therapy

Modality normalized

cell therapy

Target raw

Anti-MESO antigen receptors (CARs) T cell therapy targeting mesothelin-expressing tumors.

Target normalized

Anti-MESO antigen receptors (CARs) T cell therapy targeting mesothelin-expressing tumors.

Interventions

anti-MESO CAR-T cells, Fludarabine, Cyclophosphamide

Public preview

Source record

The MESO-CAR T cell therapy is positioned to address a significant unmet need in relapsed and refractory ovarian cancer, particularly for patients expressing mesothelin. Given the limited treatment options for this patient population, successful outcomes could establish a competitive advantage in the CAR-T therapy landscape. The collaboration with Hrain Biotechnology Co., Ltd. may enhance development capabilities and commercialization strategies. The market for ovarian cancer therapies is growing, with increasing focus on personalized medicine and immunotherapies, indicating potential for substantial market capture if the therapy demonstrates efficacy and safety.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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