TrialSignal
Clinical trial intelligence report
A Phase I/II Clinical Study to Evaluate the Safety and Efficacy of P134 Cells in the Treatment of Recurrent Glioblastoma
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT07318818
Status
RECRUITING
Phase
Phase 1/2
Sponsor
Tasly Pharmaceutical Group Co., Ltd
Executive brief
Investment-Ready Snapshot
Tasly Pharmaceutical Group's P134 cells represent a novel approach in the treatment of recurrent glioblastoma, targeting CD44 and CD133 antigens. Given the high unmet medical need in this indication, the asset has significant commercial potential. The market for glioblastoma therapies is competitive, with established treatments like temozolomide and emerging immunotherapies. Successful outcomes in this trial could position Tasly favorably against competitors, particularly if P134 demonstrates superior efficacy or safety profiles. Diligence is warranted to assess the scalability of manufacturing CAR-T cells and the regulatory pathway in various jurisdictions, particularly in light of evolving CAR-T therapy regulations.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07318818
Indication
Recurrent Glioblastoma IDH Wildtype
Modality
protein therapy
Target
CD44 and CD133 dual-targeting CAR-T cells
Intervention
P134 cell injection
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.