Report workspace

Add to folder
NCT05146336RECRUITINGanonymous

CytOSorb TreatMent Of Critically Ill PatientS Registry: International Registry on the Use of CytoSorb in the Critical Care Setting

Sponsor

Source record

CytoSorbents, Inc

Phase

Source record

Observational Registry

Modality

AI-normalized

medical device

Target

AI-normalized

CytoSorb device for hemoperfusion therapy targeting cytokine removal in critically ill patients.

Indication / condition

AI-normalized

Septic Shock

Intervention

Source record

CytoSorb

Source & freshness

Source record

NCT ID

NCT05146336

Original source

ClinicalTrials.gov

Source last updated

Sep 11, 2025

Ingested at

Jun 16, 2026

Internal sync

Jun 16, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT05146336

Title

CytOSorb TreatMent Of Critically Ill PatientS Registry: International Registry on the Use of CytoSorb in the Critical Care Setting

Sponsor

CytoSorbents, Inc

Status

RECRUITING

Phase

Observational Registry

Condition raw

Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis, Cardiogenic Shock, Pancreatitis, Acute on Chronic Liver Failure, Acute Liver Failure, Burns, Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Cytokine Release Syndrome (CRS), Extracorporeal Life Support, Postoperative Endocarditis, Hemophagocytic Lymphohistiocytoses, Liver Transplant; Complications, Infectious Disease, Postoperative Vasoplegic Syndrome, Drug Overdose, Sepsis

Condition normalized

Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis, Cardiogenic Shock, Pancreatitis, Acute on Chronic Liver Failure, Acute Liver Failure, Burns, Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Cytokine Release Syndrome (CRS), Extracorporeal Life Support, Postoperative Endocarditis, Hemophagocytic Lymphohistiocytoses, Liver Transplant; Complications, Infectious Disease, Postoperative Vasoplegic Syndrome, Drug Overdose, Sepsis

Modality raw

medical device

Modality normalized

medical device

Target raw

CytoSorb device for hemoperfusion therapy targeting cytokine removal in critically ill patients.

Target normalized

CytoSorb device for hemoperfusion therapy targeting cytokine removal in critically ill patients.

Interventions

CytoSorb

Public preview

Source record

The COSMOS registry, sponsored by CytoSorbents, Inc., aims to establish a comprehensive data repository for the use of the CytoSorb device in critical care settings. This initiative is expected to enhance the understanding of the device's efficacy in real-world applications, particularly in conditions such as septic shock and acute respiratory distress syndrome. The registry's findings could strengthen CytoSorbents' market position by providing robust clinical evidence to support the device's use, potentially leading to increased adoption in critical care units. The competitive landscape includes other hemoperfusion devices, but the unique focus on cytokine removal may provide a differentiated value proposition. Diligence considerations should include the regulatory landscape and potential reimbursement pathways for the device.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account

Create a free account first, then unlock a single report, buy credits or subscribe.