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NCT07441980NOT_YET_RECRUITINGanonymous

A Clinical Study to Investigate the Safety and Efficacy of CT1390B in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Sponsor

Source record

Institute of Hematology & Blood Diseases Hospital, China

Phase

Source record

Phase 1

Modality

AI-normalized

cell therapy

Target

AI-normalized

CLL-1 positive cells in relapsed/refractory acute myeloid leukemia (AML)

Indication / condition

AI-normalized

Relapsed/Refractory Acute Myeloid Leukemia(AML)

Intervention

Source record

CAR-T cells chimeric antigen receptor T cells

Source & freshness

Source record

NCT ID

NCT07441980

Original source

ClinicalTrials.gov

Source last updated

Mar 02, 2026

Ingested at

Jun 16, 2026

Internal sync

Jun 16, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT07441980

Title

A Clinical Study to Investigate the Safety and Efficacy of CT1390B in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Sponsor

Institute of Hematology & Blood Diseases Hospital, China

Status

NOT_YET_RECRUITING

Phase

Phase 1

Condition raw

Relapsed/Refractory Acute Myeloid Leukemia(AML)

Condition normalized

Relapsed/Refractory Acute Myeloid Leukemia(AML)

Modality raw

cell therapy

Modality normalized

cell therapy

Target raw

CLL-1 positive cells in relapsed/refractory acute myeloid leukemia (AML)

Target normalized

CLL-1 positive cells in relapsed/refractory acute myeloid leukemia (AML)

Interventions

CAR-T cells chimeric antigen receptor T cells

Public preview

Source record

CT1390B is positioned to address a significant unmet need in the treatment of relapsed/refractory acute myeloid leukemia (AML), particularly among patients who are CLL-1 positive. The trial is sponsored by the Institute of Hematology & Blood Diseases Hospital in China, indicating a strong local expertise in hematological malignancies. The market for AML therapies is competitive, with several CAR-T therapies in development; however, CT1390B's unique targeting of CLL-1 may provide a differentiated approach. Given the estimated enrollment of 9-18 participants, the trial's results could have implications for future development and partnerships, particularly if safety and efficacy are demonstrated. The trial is not yet recruiting, with an estimated start date in March 2026, which may affect the timeline for potential market entry.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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