TrialSignal
Clinical trial intelligence report
A Clinical Study to Investigate the Safety and Efficacy of CT1390B in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT07441980
Status
NOT_YET_RECRUITING
Phase
Phase 1
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Executive brief
Investment-Ready Snapshot
CT1390B is positioned to address a significant unmet need in the treatment of relapsed/refractory acute myeloid leukemia (AML), particularly among patients who are CLL-1 positive. The trial is sponsored by the Institute of Hematology & Blood Diseases Hospital in China, indicating a strong local expertise in hematological malignancies. The market for AML therapies is competitive, with several CAR-T therapies in development; however, CT1390B's unique targeting of CLL-1 may provide a differentiated approach. Given the estimated enrollment of 9-18 participants, the trial's results could have implications for future development and partnerships, particularly if safety and efficacy are demonstrated. The trial is not yet recruiting, with an estimated start date in March 2026, which may affect the timeline for potential market entry.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07441980
Indication
Relapsed/Refractory Acute Myeloid Leukemia(AML)
Modality
cell therapy
Target
CLL-1 positive cells in relapsed/refractory acute myeloid leukemia (AML)
Intervention
CAR-T cells chimeric antigen receptor T cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.