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Clinical trial intelligence report
The Effect of Live Attenuated Inactivated Influenza Vaccine on Experimental Human Pneumococcal Carriage Study
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT03502291
Status
COMPLETED
Phase
Phase 4
Sponsor
Liverpool University Hospitals NHS Foundation Trust
Executive brief
Investment-Ready Snapshot
The study investigates the impact of the Live Attenuated Influenza Vaccine (LAIV) on pneumococcal carriage, which is crucial given the rising concerns over secondary bacterial infections during influenza outbreaks. The findings could influence vaccination strategies and public health policies, particularly in pediatric populations where LAIV is already licensed. If LAIV is shown to enhance pneumococcal carriage, it may necessitate a reevaluation of its use in mass immunization campaigns, potentially affecting market dynamics for both LAIV and pneumococcal vaccines. Competitively, this study positions Liverpool University Hospitals NHS Foundation Trust and its collaborators at the forefront of research addressing the intersection of influenza and pneumococcal disease, which could lead to new insights and product development opportunities.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03502291
Indication
Pneumonia
Modality
protein therapy
Target
Streptococcus pneumoniae nasal carriage dynamics and immune response modulation via Live Attenuated Influenza Vaccine (LAIV).
Intervention
Study one: LAIV + Inoculation, Study one: Placebo + Inoculation, Study two: Inoculation + LAIV, Study two: Inoculation + placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.