Report workspace

Add to folder
NCT03502291COMPLETEDanonymous

The Effect of Live Attenuated Inactivated Influenza Vaccine on Experimental Human Pneumococcal Carriage Study

Sponsor

Source record

Liverpool University Hospitals NHS Foundation Trust

Phase

Source record

Phase 4

Modality

AI-normalized

protein therapy

Target

AI-normalized

Streptococcus pneumoniae nasal carriage dynamics and immune response modulation via Live Attenuated Influenza Vaccine (LAIV).

Indication / condition

AI-normalized

Pneumonia

Intervention

Source record

Study one: LAIV + Inoculation, Study one: Placebo + Inoculation, Study two: Inoculation + LAIV, Study two: Inoculation + placebo

Source & freshness

Source record

NCT ID

NCT03502291

Original source

ClinicalTrials.gov

Source last updated

Apr 18, 2018

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT03502291

Title

The Effect of Live Attenuated Inactivated Influenza Vaccine on Experimental Human Pneumococcal Carriage Study

Sponsor

Liverpool University Hospitals NHS Foundation Trust

Status

COMPLETED

Phase

Phase 4

Condition raw

Pneumonia, Influenza, Human

Condition normalized

Pneumonia, Influenza, Human

Modality raw

protein therapy

Modality normalized

protein therapy

Target raw

Streptococcus pneumoniae nasal carriage dynamics and immune response modulation via Live Attenuated Influenza Vaccine (LAIV).

Target normalized

Streptococcus pneumoniae nasal carriage dynamics and immune response modulation via Live Attenuated Influenza Vaccine (LAIV).

Interventions

Study one: LAIV + Inoculation, Study one: Placebo + Inoculation, Study two: Inoculation + LAIV, Study two: Inoculation + placebo

Public preview

Source record

The study investigates the impact of the Live Attenuated Influenza Vaccine (LAIV) on pneumococcal carriage, which is crucial given the rising concerns over secondary bacterial infections during influenza outbreaks. The findings could influence vaccination strategies and public health policies, particularly in pediatric populations where LAIV is already licensed. If LAIV is shown to enhance pneumococcal carriage, it may necessitate a reevaluation of its use in mass immunization campaigns, potentially affecting market dynamics for both LAIV and pneumococcal vaccines. Competitively, this study positions Liverpool University Hospitals NHS Foundation Trust and its collaborators at the forefront of research addressing the intersection of influenza and pneumococcal disease, which could lead to new insights and product development opportunities.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account

Create a free account first, then unlock a single report, buy credits or subscribe.