TrialSignal
Clinical trial intelligence report
Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Patients With Alzheimer's Disease: A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre Study of 12 Weeks
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT02471196
Status
COMPLETED
Phase
Phase 2
Sponsor
Orion Corporation, Orion Pharma
Executive brief
Investment-Ready Snapshot
ORM-12741, developed by Orion Corporation in collaboration with Janssen Pharmaceuticals, targets agitation and aggression symptoms in Alzheimer's disease, a significant unmet need in the market. The Alzheimer's disease therapeutics market is projected to grow substantially, driven by increasing prevalence and demand for effective treatments. The competitive landscape includes established therapies like cholinesterase inhibitors and memantine, but there remains a gap for targeted neuropsychiatric symptom management. Successful outcomes from this trial could position ORM-12741 as a novel treatment option, potentially enhancing Orion's portfolio and market share in the neurodegenerative disease space.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02471196
Indication
Alzheimer's Disease
Modality
small molecule
Target
Alpha-2C adrenoceptor (AR)
Intervention
ORM-12741, ORM-12741, Placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.