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NCT00842920UNKNOWNanonymous

Randomized Controlled Trial of Simvastatin in Amnestic MCI Patients

Sponsor

Source record

Charite University, Berlin, Germany

Phase

Source record

Phase 4

Modality

AI-normalized

small molecule

Target

AI-normalized

Amyloid production in the brain related to Alzheimer's dementia.

Indication / condition

AI-normalized

Mild Cognitive Impairment

Intervention

Source record

Simvastatin 60 mg, Placebo, Simvastatin 20 mg

Source & freshness

Source record

NCT ID

NCT00842920

Original source

ClinicalTrials.gov

Source last updated

Jan 27, 2020

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT00842920

Title

Randomized Controlled Trial of Simvastatin in Amnestic MCI Patients

Sponsor

Charite University, Berlin, Germany

Status

UNKNOWN

Phase

Phase 4

Condition raw

Mild Cognitive Impairment

Condition normalized

Mild Cognitive Impairment

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Amyloid production in the brain related to Alzheimer's dementia.

Target normalized

Amyloid production in the brain related to Alzheimer's dementia.

Interventions

Simvastatin 60 mg, Placebo, Simvastatin 20 mg

Public preview

Source record

The clinical trial sponsored by Charite University aims to evaluate the efficacy of Simvastatin in reducing cognitive decline in patients with Mild Cognitive Impairment (MCI), a precursor to Alzheimer's disease. If successful, this study could position Simvastatin as a potential preventive treatment for Alzheimer's, tapping into a significant market given the rising prevalence of dementia globally. The competitive landscape includes other anti-dementia therapies, but Simvastatin's established safety profile as a cholesterol-lowering agent may provide a unique advantage. The trial's outcomes could influence market dynamics, particularly if they demonstrate a clear benefit over existing treatments. Diligence should focus on the trial's recruitment status and any emerging data that may affect market entry timelines.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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