Report workspace

Add to folder
NCT07115446RECRUITINGanonymous

A Phase Ib Study to Explore the Safety, Tolerability, and Pharmacokinetics of HS-20093 Combination With HRS-5041 in Patients With Advanced Prostate Cancer

Sponsor

Source record

Hansoh BioMedical R&D Company

Phase

Source record

Phase 1b

Modality

AI-normalized

small molecule

Target

AI-normalized

B7-H3 (CD276) and androgen receptors (AR)

Indication / condition

AI-normalized

Advanced Prostate Cancer

Intervention

Source record

HS-20093, HRS-5041

Source & freshness

Source record

NCT ID

NCT07115446

Original source

ClinicalTrials.gov

Source last updated

Dec 05, 2025

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT07115446

Title

A Phase Ib Study to Explore the Safety, Tolerability, and Pharmacokinetics of HS-20093 Combination With HRS-5041 in Patients With Advanced Prostate Cancer

Sponsor

Hansoh BioMedical R&D Company

Status

RECRUITING

Phase

Phase 1b

Condition raw

Advanced Prostate Cancer

Condition normalized

Advanced Prostate Cancer

Modality raw

small molecule

Modality normalized

small molecule

Target raw

B7-H3 (CD276) and androgen receptors (AR)

Target normalized

B7-H3 (CD276) and androgen receptors (AR)

Interventions

HS-20093, HRS-5041

Public preview

Source record

HS-20093, a fully humanized IgG1 antibody-drug conjugate targeting B7-H3, is being evaluated in combination with HRS-5041, a PROTAC targeting androgen receptors, for the treatment of advanced prostate cancer. The market for prostate cancer therapies is significant, with a growing demand for innovative treatments, particularly for metastatic castration-resistant prostate cancer (mCRPC). The combination approach may provide a competitive edge over existing therapies by targeting multiple pathways involved in tumor progression. The trial's success could position Hansoh BioMedical favorably within the oncology space, potentially leading to partnerships or licensing opportunities. However, the competitive landscape includes established players with advanced therapies, necessitating a thorough diligence process to assess market entry strategies and potential barriers.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account

Create a free account first, then unlock a single report, buy credits or subscribe.