TrialSignal
Clinical trial intelligence report
IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos Patients
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 16, 2026
NCT ID
NCT01446783
Status
COMPLETED
Phase
Not Applicable
Sponsor
Bispebjerg Hospital
Executive brief
Investment-Ready Snapshot
The clinical trial conducted by Bispebjerg Hospital investigates the potential of IGF-I (mecasermin) to enhance collagen synthesis in patients with Ehlers-Danlos syndrome (EDS), a rare connective tissue disorder. Given the limited treatment options for EDS, a successful outcome could position mecasermin as a novel therapeutic approach, potentially capturing a niche market. The trial's completion in 2012 suggests that data may be available for further analysis, which could inform future development strategies. Competitive implications include the need to assess other therapies targeting collagen synthesis or connective tissue disorders, as well as the potential for partnerships or licensing opportunities based on trial outcomes.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01446783
Indication
Ehlers-Danlos Syndrome, Classic
Modality
small molecule
Target
Insulin-like growth factor-I (IGF-I) signaling pathway, specifically its role in collagen synthesis.
Intervention
mecasermin, Saline
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.