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NCT06869382COMPLETEDanonymous

Comparative Analysis of ICS Combined with LABA Versus Addition of Omalizumab on Transcriptomic Expression Profiles in Patients with Allergic Asthma

Sponsor

Source record

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Phase

Source record

Phase 4

Modality

AI-normalized

small molecule

Target

AI-normalized

Immunoglobulin E (IgE) and associated inflammatory pathways in allergic asthma.

Indication / condition

AI-normalized

Asthma Patients

Intervention

Source record

Foster BDP/Formoterol, Omalizimab

Source & freshness

Source record

NCT ID

NCT06869382

Original source

ClinicalTrials.gov

Source last updated

Mar 11, 2025

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT06869382

Title

Comparative Analysis of ICS Combined with LABA Versus Addition of Omalizumab on Transcriptomic Expression Profiles in Patients with Allergic Asthma

Sponsor

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Status

COMPLETED

Phase

Phase 4

Condition raw

Asthma Patients

Condition normalized

Asthma Patients

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Immunoglobulin E (IgE) and associated inflammatory pathways in allergic asthma.

Target normalized

Immunoglobulin E (IgE) and associated inflammatory pathways in allergic asthma.

Interventions

Foster BDP/Formoterol, Omalizimab

Public preview

Source record

The study investigates the comparative efficacy of ICS+LABA versus ICS+LABA+Omalizumab in patients with allergic asthma, addressing a significant unmet need in asthma management. With approximately 334 million asthma patients globally, the market for asthma therapeutics, particularly biologics like Omalizumab, is substantial and growing. The insights gained from transcriptomic analysis may lead to improved personalized treatment strategies, enhancing patient outcomes and potentially increasing market share for the involved therapies. The findings could also inform future product development and positioning against competitors in the asthma biologics space.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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