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NCT05315778UNKNOWNanonymous

Anti-BCMA CAR T-Cell Therapy for Relapsed/Refractory Immune Thrombocytopenia

Sponsor

Source record

The First Affiliated Hospital of Soochow University

Phase

Source record

Phase 2

Modality

AI-normalized

protein therapy

Target

AI-normalized

BCMA (B-cell maturation antigen)

Indication / condition

AI-normalized

ITP

Intervention

Source record

autologous anti-BCMA chimeric antigen receptor T cells

Source & freshness

Source record

NCT ID

NCT05315778

Original source

ClinicalTrials.gov

Source last updated

Apr 07, 2022

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT05315778

Title

Anti-BCMA CAR T-Cell Therapy for Relapsed/Refractory Immune Thrombocytopenia

Sponsor

The First Affiliated Hospital of Soochow University

Status

UNKNOWN

Phase

Phase 2

Condition raw

ITP

Condition normalized

ITP

Modality raw

protein therapy

Modality normalized

protein therapy

Target raw

BCMA (B-cell maturation antigen)

Target normalized

BCMA (B-cell maturation antigen)

Interventions

autologous anti-BCMA chimeric antigen receptor T cells

Public preview

Source record

The study evaluates the efficacy and safety of Anti-BCMA CAR T-cell therapy in patients with relapsed/refractory immune thrombocytopenia (R/R ITP). Given the limited treatment options for R/R ITP, successful outcomes could position this therapy as a novel intervention in a niche market. The collaboration with Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd. may enhance development capabilities and commercialization potential. However, the competitive landscape includes other emerging therapies targeting similar patient populations, necessitating a robust differentiation strategy based on clinical efficacy and safety profiles.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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