Report workspace

Add to folder
NCT06092047RECRUITINGanonymous

Clinical Study of Universal Off-the-shelf Cell Products in Patients With CD19-positive Relapsed/Refractory B-cell Hematolymphatic Malignancies.

Sponsor

Source record

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Phase

Source record

Early Phase 1

Modality

AI-normalized

protein therapy

Target

AI-normalized

CD19-positive B-cell hematolymphatic malignancies

Indication / condition

AI-normalized

CD19-positive Relapsed or Refractory B-cell Malignancies

Intervention

Source record

UTAA09 cells for infusion, Fludarabine, Cyclophosphamide

Source & freshness

Source record

NCT ID

NCT06092047

Original source

ClinicalTrials.gov

Source last updated

May 16, 2025

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT06092047

Title

Clinical Study of Universal Off-the-shelf Cell Products in Patients With CD19-positive Relapsed/Refractory B-cell Hematolymphatic Malignancies.

Sponsor

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Status

RECRUITING

Phase

Early Phase 1

Condition raw

CD19-positive Relapsed or Refractory B-cell Malignancies

Condition normalized

CD19-positive Relapsed or Refractory B-cell Malignancies

Modality raw

protein therapy

Modality normalized

protein therapy

Target raw

CD19-positive B-cell hematolymphatic malignancies

Target normalized

CD19-positive B-cell hematolymphatic malignancies

Interventions

UTAA09 cells for infusion, Fludarabine, Cyclophosphamide

Public preview

Source record

PersonGen BioTherapeutics is advancing a novel therapeutic approach utilizing allogeneic γδT cells transduced with an anti-CD19 lentiviral vector for the treatment of relapsed/refractory B-cell malignancies. This asset targets a significant unmet need in the oncology market, particularly for patients who have limited options after multiple lines of therapy. The competitive landscape includes established CAR-T therapies, but the off-the-shelf nature of UTAA09 may provide logistical and cost advantages. Given the increasing prevalence of B-cell malignancies, successful outcomes could position PersonGen favorably in a growing market segment. Diligence should focus on the safety profile, potential for rapid commercialization, and regulatory pathways in key markets, particularly in China and the US.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

Report access

Create an account to unlock this report

Choose the access model that matches the job: one urgent report, reusable credits for project work, or unlimited monthly access with AI and folders.

Full protocol, outcomes, eligibility, contacts and results sections
Patent/IP landscape with verified records when available
Board-ready PDF export with source provenance
Save to folders and synthesize multiple assets in premium workspace
Create account

Create a free account first, then unlock a single report, buy credits or subscribe.