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NCT02911948COMPLETEDanonymous

A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs

Sponsor

Source record

Novo Nordisk A/S

Phase

Source record

Phase 3

Modality

AI-normalized

small molecule

Target

AI-normalized

Insulin receptors and GLP-1 receptors

Indication / condition

AI-normalized

Diabetes

Intervention

Source record

Insulin degludec/liraglutide, Insulin degludec

Source & freshness

Source record

NCT ID

NCT02911948

Original source

ClinicalTrials.gov

Source last updated

Apr 09, 2021

Ingested at

Jun 13, 2026

Internal sync

Jun 13, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT02911948

Title

A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs

Sponsor

Novo Nordisk A/S

Status

COMPLETED

Phase

Phase 3

Condition raw

Diabetes, Diabetes Mellitus, Type 2

Condition normalized

Diabetes, Diabetes Mellitus, Type 2

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Insulin receptors and GLP-1 receptors

Target normalized

Insulin receptors and GLP-1 receptors

Interventions

Insulin degludec/liraglutide, Insulin degludec

Public preview

Source record

The trial investigates the efficacy and safety of insulin degludec/liraglutide versus insulin degludec in Japanese patients with inadequately controlled Type 2 Diabetes Mellitus (T2DM). Given the increasing prevalence of diabetes in Japan and the growing demand for effective treatment options, this dual-action therapy could capture significant market share. The competitive landscape includes established insulin therapies and GLP-1 receptor agonists, necessitating a robust differentiation strategy. Diligence should focus on regulatory pathways and potential reimbursement scenarios in Japan, where diabetes management is a priority.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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