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The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 13, 2026
NCT ID
NCT04588649
Status
COMPLETED
Phase
Phase 2
Sponsor
Chang Gung Memorial Hospital
Executive brief
Investment-Ready Snapshot
The study, sponsored by Chang Gung Memorial Hospital, investigates the interplay between vascular injury, amyloid plaques, and tau proteins in cognitive dysfunction following stroke. With approximately one-third of stroke patients developing post-stroke dementia, this research addresses a significant unmet medical need in the aging population. The findings could inform the development of diagnostic tools or therapeutic strategies targeting cognitive impairment in stroke patients, potentially positioning the sponsor as a leader in this niche market. The competitive landscape includes other neuroimaging studies and dementia-related therapeutics, necessitating a thorough diligence assessment to identify potential collaborators or competitors in the field.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04588649
Indication
Post-stroke Dementia
Modality
small molecule
Target
Vascular injury, amyloid plaque, and tau protein as contributors to cognitive dysfunction post-stroke.
Intervention
THK-5351, AV-45
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.