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NCT03392298UNKNOWNanonymous

Investigation of Signal Pathway Induced by Colla Corri Asini Regulating Globin Level in Beta Thalassemia Patients With Pregnancy Anemia

Sponsor

Source record

The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine

Phase

Source record

Phase 4

Modality

AI-normalized

small molecule

Target

AI-normalized

Regulation of globin gene expression pathways in beta-thalassemia patients, specifically targeting alpha, beta, gamma, and delta globin levels.

Indication / condition

AI-normalized

Thalassemia

Intervention

Source record

Colla corii asini

Source & freshness

Source record

NCT ID

NCT03392298

Original source

ClinicalTrials.gov

Source last updated

Jan 16, 2018

Ingested at

Jun 12, 2026

Internal sync

Jun 12, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT03392298

Title

Investigation of Signal Pathway Induced by Colla Corri Asini Regulating Globin Level in Beta Thalassemia Patients With Pregnancy Anemia

Sponsor

The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine

Status

UNKNOWN

Phase

Phase 4

Condition raw

Thalassemia, Pregnancy

Condition normalized

Thalassemia, Pregnancy

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Regulation of globin gene expression pathways in beta-thalassemia patients, specifically targeting alpha, beta, gamma, and delta globin levels.

Target normalized

Regulation of globin gene expression pathways in beta-thalassemia patients, specifically targeting alpha, beta, gamma, and delta globin levels.

Interventions

Colla corii asini

Public preview

Source record

The study investigates the efficacy of Colla corii asini (CCA) in treating anemia in pregnant women with beta-thalassemia, a significant health concern in regions with high thalassemia prevalence, such as Southern China. The potential market for CCA as a therapeutic agent could be substantial, given the lack of safe and effective treatments for this demographic. The findings may position CCA as a viable alternative to conventional therapies, which often have severe side effects. Competitive analysis indicates a niche market with limited direct competition in the use of traditional Chinese medicine for this indication, presenting an opportunity for differentiation and market entry. Diligence implications include the need for thorough evaluation of safety and efficacy data, as well as potential regulatory pathways for traditional medicine integration into standard care.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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