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NCT05032937COMPLETEDanonymous

Clinical Study of Domestic Polysaccharide Superparamagnetic Iron Oxide Nanoparticle Injection for Coronary Artery Contrast-enhanced Magnetic Resonance Contrast-enhanced Angiography

Sponsor

Source record

The First Affiliated Hospital with Nanjing Medical University

Phase

Source record

PHASE1

Modality

AI-normalized

small molecule

Target

AI-normalized

domestic polysaccharide superparamagnetic iron oxide nanoparticle

Indication / condition

AI-normalized

Coronary Heart Disease

Intervention

Source record

domestic polysaccharide superparamagnetic iron oxide nanoparticle

Source & freshness

Source record

NCT ID

NCT05032937

Original source

ClinicalTrials.gov

Source last updated

Jan 13, 2023

Ingested at

Jun 11, 2026

Internal sync

Jun 11, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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NCT ID

NCT05032937

Title

Clinical Study of Domestic Polysaccharide Superparamagnetic Iron Oxide Nanoparticle Injection for Coronary Artery Contrast-enhanced Magnetic Resonance Contrast-enhanced Angiography

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Status

COMPLETED

Phase

PHASE1

Condition raw

Coronary Heart Disease

Condition normalized

Coronary Heart Disease

Modality raw

small molecule

Modality normalized

small molecule

Target raw

domestic polysaccharide superparamagnetic iron oxide nanoparticle

Target normalized

domestic polysaccharide superparamagnetic iron oxide nanoparticle

Interventions

domestic polysaccharide superparamagnetic iron oxide nanoparticle

Public preview

Source record

This is a single-center, prospective, controlled and diagnostic clinical trial which will enroll 30 patients scheduled for coronary angiography in China.Patients will receive contrast-enhanced cardiac magnetic resonance with polysaccharide superparamagnetic iron oxide nanoparticle before percutaneous coronary angiography.In order to evaluate the safety of polysaccharide superparamagnetic iron oxide nanoparticle, patients will detect iron levels in peripheral and tissue before and after the examination.The main indicators of the study are the degree of coronary artery stenosis and the stability of coronary atherosclerotic plaque assessed by contrast-enhanced cardiac magnetic resonance with polysaccharide superparamagnetic iron oxide nanoparticle.

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