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NCT04231916COMPLETEDanonymous

High Resolution Thermal Imaging to Identify Vertebral Fractures in Children and Young People With Osteogenesis Imperfecta

Sponsor

Source record

Sheffield Children's NHS Foundation Trust

Phase

Source record

NA

Modality

AI-normalized

medical device

Target

AI-normalized

Thermal imaging device

Indication / condition

AI-normalized

Osteogenesis Imperfecta

Intervention

Source record

Thermal imaging device

Source & freshness

Source record

NCT ID

NCT04231916

Original source

ClinicalTrials.gov

Source last updated

Jan 18, 2020

Ingested at

Jun 11, 2026

Internal sync

Jun 11, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT04231916

Title

High Resolution Thermal Imaging to Identify Vertebral Fractures in Children and Young People With Osteogenesis Imperfecta

Sponsor

Sheffield Children's NHS Foundation Trust

Status

COMPLETED

Phase

NA

Condition raw

Osteogenesis Imperfecta

Condition normalized

Osteogenesis Imperfecta

Modality raw

medical device

Modality normalized

medical device

Target raw

Thermal imaging device

Target normalized

Thermal imaging device

Interventions

Thermal imaging device

Public preview

Source record

Brittle bone disease also known as osteogenesis imperfecta (OI) is characterised by a defect in the bone tissue that leads to recurrent fractures and significant bone deformities in children. These fractures include vertebral (spinal) fractures. As a result, child with OI require regular clinic surveillance that includes repeated xrays of the spine. in our pilot study the investigators plan to use a thermal imaging camera that can pick up changes in temperature to 0.03 degrees to determine whether the investigators can accurately identify vertebral fractures without the need for radiation. in the first part of the study the investigators will compare the thermal images from the camera with the xrays to see if the investigators can pick up the vertebral fractures seen on the xray picture. If this is possible, then the investigators will move on to phase 2 of the study which will investigate the ability of the thermal camera to pick up vertebral fractures without prior knowledge of where the fractures are located. If this approach is successful this will help us to develop a nonradiation, lowcost painless way of identifying vertebral fractures in children with OI.

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