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NCT07125911COMPLETEDanonymous

COMPARISON OF THE EFFECT OF COMMON ANALGESICS ON PULPAL SENSIBILITY TESTS: A CLINICAL TRIAL

Sponsor

Source record

HITEC-Institute of Medical Sciences

Phase

Source record

NA

Modality

AI-normalized

small molecule

Target

AI-normalized

Ibuprofen 400 mg (if necessary), Paracetamol 500 mg

Indication / condition

AI-normalized

Irreversible Pulpitis With Apical Periodontitis

Intervention

Source record

Ibuprofen 400 mg (if necessary), Paracetamol 500 mg

Source & freshness

Source record

NCT ID

NCT07125911

Original source

ClinicalTrials.gov

Source last updated

Aug 15, 2025

Ingested at

Jun 09, 2026

Internal sync

Jun 09, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

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View original source fields

NCT ID

NCT07125911

Title

COMPARISON OF THE EFFECT OF COMMON ANALGESICS ON PULPAL SENSIBILITY TESTS: A CLINICAL TRIAL

Sponsor

HITEC-Institute of Medical Sciences

Status

COMPLETED

Phase

NA

Condition raw

Irreversible Pulpitis With Apical Periodontitis

Condition normalized

Irreversible Pulpitis With Apical Periodontitis

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Ibuprofen 400 mg (if necessary), Paracetamol 500 mg

Target normalized

Ibuprofen 400 mg (if necessary), Paracetamol 500 mg

Interventions

Ibuprofen 400 mg (if necessary), Paracetamol 500 mg

Public preview

Source record

his study will investigate whether commonly used analgesics - 400 mg ibuprofen and 500 mg paracetamol - influence the accuracy of pulpal sensibility tests (cold test and electric pulp test) in patients with symptomatic irreversible pulpitis. Analgesics are often taken prior to dental visits and may mask endodontic symptoms, affecting diagnosis. Participants will be randomly assigned to receive either ibuprofen or paracetamol in a double-blind design. Test responses and pain levels will be measured before and 30 minutes after medication to assess any masking effect.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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