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NCT02640092COMPLETEDanonymous

Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Patients With Prodromal, Mild, and Moderate Alzheimer's Disease Compared to Healthy Volunteers

Sponsor

Source record

Genentech, Inc.

Phase

Source record

Phase 1

Modality

AI-normalized

small molecule

Target

AI-normalized

Tau protein in the brain

Indication / condition

AI-normalized

Alzheimer's Disease

Intervention

Source record

[18F]GTP1

Source & freshness

Source record

NCT ID

NCT02640092

Original source

ClinicalTrials.gov

Source last updated

Dec 23, 2019

Ingested at

Jun 08, 2026

Internal sync

Jun 08, 2026

Model version

trialsignal-ai-v1

Normalized confidence

96%

Validation status

validated

Open original registry record
View original source fields

NCT ID

NCT02640092

Title

Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Patients With Prodromal, Mild, and Moderate Alzheimer's Disease Compared to Healthy Volunteers

Sponsor

Genentech, Inc.

Status

COMPLETED

Phase

Phase 1

Condition raw

Alzheimer's Disease

Condition normalized

Alzheimer's Disease

Modality raw

small molecule

Modality normalized

small molecule

Target raw

Tau protein in the brain

Target normalized

Tau protein in the brain

Interventions

[18F]GTP1

Public preview

Source record

Genentech's [18F]GTP1 is positioned within the growing market for Alzheimer's disease diagnostics, particularly in imaging tau pathology. The completion of this Phase 1 study suggests a potential pathway for further development and commercialization, especially as the demand for accurate diagnostic tools in Alzheimer's disease increases. The competitive landscape includes other tau imaging agents, but [18F]GTP1's unique properties may provide differentiation. Diligence should focus on the regulatory pathway and potential partnerships for broader clinical application.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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