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NCT01977482COMPLETEDanonymous

A Phase IIB, Randomized, Blinded, Dose-ranging, Active-controlled, Parallel-group, Multi-center Study to Evaluate the Dose Response Relationship of GSK1278863 Over the First 4 Weeks of Treatment and Evaluate the Safety and Efficacy of GSK1278863 Over 24 Weeks in Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Switch From Recombinant Human Erythropoietin

Sponsor

Source record

GlaxoSmithKline

Phase

Source record

Phase IIB

Modality

AI-normalized

small molecule

Target

AI-normalized

GSK1278863 for anemia in hemodialysis-dependent chronic kidney disease patients

Indication / condition

AI-normalized

Anaemia

Intervention

Source record

GSK1278863, Placebo, rhEPO

Source & freshness

Source record

NCT ID

NCT01977482

Original source

ClinicalTrials.gov

Source last updated

Jun 08, 2018

Ingested at

May 31, 2026

Internal sync

Jun 05, 2026

Model version

trialsignal-ai-v1

Normalized confidence

88%

Validation status

validated

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View original source fields

NCT ID

NCT01977482

Title

A Phase IIB, Randomized, Blinded, Dose-ranging, Active-controlled, Parallel-group, Multi-center Study to Evaluate the Dose Response Relationship of GSK1278863 Over the First 4 Weeks of Treatment and Evaluate the Safety and Efficacy of GSK1278863 Over 24 Weeks in Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Switch From Recombinant Human Erythropoietin

Sponsor

GlaxoSmithKline

Status

COMPLETED

Phase

Phase IIB

Condition raw

Anaemia

Condition normalized

Anaemia

Modality raw

Anaemia

Modality normalized

small molecule

Target raw

GSK1278863 for anemia in hemodialysis-dependent chronic kidney disease patients

Target normalized

GSK1278863 for anemia in hemodialysis-dependent chronic kidney disease patients

Interventions

GSK1278863, Placebo, rhEPO

Public preview

Source record

This clinical trial evaluated the dose-response relationship, safety, and efficacy of GSK1278863 in maintaining hemoglobin levels in hemodialysis-dependent subjects with anemia due to chronic kidney disease. The study aimed to optimize dosing regimens for future Phase 3 trials.

AI-generated analysis supports research triage only. Verify source records, publications, sponsor disclosures and IP databases before making diligence decisions. Model: trialsignal-ai-v1.

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TrialSignal

Clinical trial intelligence report

A Phase IIB, Randomized, Blinded, Dose-ranging, Active-controlled, Parallel-group, Multi-center Study to Evaluate the Dose Response Relationship of GSK1278863 Over the First 4 Weeks of Treatment and Evaluate the Safety and Efficacy of GSK1278863 Over 24 Weeks in Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Switch From Recombinant Human Erythropoietin

Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.

Generated

Jun 13, 2026

NCT ID

NCT01977482

Status

COMPLETED

Phase

Phase IIB

Sponsor

GlaxoSmithKline

Executive brief

Investment-Ready Snapshot

This clinical trial evaluated the dose-response relationship, safety, and efficacy of GSK1278863 in maintaining hemoglobin levels in hemodialysis-dependent subjects with anemia due to chronic kidney disease. The study aimed to optimize dosing regimens for future Phase 3 trials.

Source & freshness

Provenance

SourceClinicalTrials.gov
Source updatedJun 08, 2018
Internal syncJun 05, 2026
Model versiontrialsignal-ai-v1

https://clinicaltrials.gov/study/NCT01977482

Indication

Anaemia

Modality

small molecule

Target

GSK1278863 for anemia in hemodialysis-dependent chronic kidney disease patients

Intervention

GSK1278863, Placebo, rhEPO

Source record

Protocol Description

Detailed source ingestion pending.

Source record

Outcome Measures

Detailed source ingestion pending.

Source record

Eligibility

Detailed source ingestion pending.

AI analysis

Known Results And Readout Context

Detailed source ingestion pending.

IP intelligence

Patent And IP Landscape

Detailed source ingestion pending.

Source record

Contacts

Detailed source ingestion pending.